Oral drop pills for treating bronchitis and preparation method thereof
A technology of bronchitis and drop pills, which is applied in the field of oral drop pills for the treatment of bronchitis and its preparation, which can solve the problems of long dissolution time, low dissolution rate, inaccurate dosage, etc., and avoid gastrointestinal irritation Symptoms, faster dissolution and absorption, and improved bioavailability
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[0035] Now with several groups of specific examples, the preparation method of the Shuke loquat dropping pills of the present invention will be further described.
[0036] Group 1: Tests with a single matrix
[0037] 1. According to [Preparation Method] 1 and [Appendix: A preparation method of a traditional Chinese medicine extract], the extract dry powder containing loquat leaves, ephedra, platycodon, polygala and other four pure active ingredients of traditional Chinese medicines was prepared for use;
[0038] 2. Accurately weigh ammonium chloride and menthol according to the formula for subsequent use;
[0039] 3. Matrix: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. pharmaceutical carrier;
[0040] 4. Proportion: take g or kg as the unit, by weight, (drug extract+ammonium chloride+menthol): matri...
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