Oral drop pills for treating bronchitis and preparation method thereof

A technology of bronchitis and drop pills, which is applied in the field of oral drop pills for the treatment of bronchitis and its preparation, which can solve the problems of long dissolution time, low dissolution rate, inaccurate dosage, etc., and avoid gastrointestinal irritation Symptoms, faster dissolution and absorption, and improved bioavailability

Inactive Publication Date: 2005-07-06
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

[0009] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
However, syrup preparations also have the disadvantages of low drug content, large doses, inaccurate doses, inconvenient taking, and inconvenient carrying.
[0010] In addition, conventional oral dosage forms, such

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0035] Now with several groups of specific examples, the preparation method of the Shuke loquat dropping pills of the present invention will be further described.

[0036] Group 1: Tests with a single matrix

[0037] 1. According to [Preparation Method] 1 and [Appendix: A preparation method of a traditional Chinese medicine extract], the extract dry powder containing loquat leaves, ephedra, platycodon, polygala and other four pure active ingredients of traditional Chinese medicines was prepared for use;

[0038] 2. Accurately weigh ammonium chloride and menthol according to the formula for subsequent use;

[0039] 3. Matrix: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. pharmaceutical carrier;

[0040] 4. Proportion: take g or kg as the unit, by weight, (drug extract+ammonium chloride+menthol): matri...

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Abstract

The invention relates to a medicinal oral preparation, i.e., cough-relieving loquat drop pill, which has the functions of yin-nourishing, arresting persistent cough, removing the phlegm and treating chronic cough and bronchitis. The drop pill has the advantages of high biological availability, quick-speed medicine release, quick-speed effect, less toxic and side effects, higher medicinal content, smaller amount of administration, accurate administration dosage, easy administering, low price, and facilitated carrying. The drop pill is prepared through the conventional loquat syrup preparing processes.

Description

technical field [0001] The present invention relates to a kind of medicinal composition with the function of nourishing yin and astringing the lung, antitussive and expectorant, which is used for treating chronic cough, overworked cough, bronchitis and other symptoms. Formed a kind of pharmaceutical composition oral drop pill preparation. Background technique [0002] According to the ministerial drug standard WS 3 -The cough loquat syrup prepared by the formula and extraction process given in B-3004-98 is an oral syrup-like pure Chinese medicine preparation for the treatment of chronic cough, labor cough, bronchitis and other symptoms. It has been clinically verified with stable quality and curative effect Indeed, it is a commonly used pharmaceutical preparation for clinical and family treatment of the above diseases. [0003] The following is the drug standard WS 3 -The formula, extraction process and brief description of the cough loquat syrup given in B-3004-98: [0...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61P11/00
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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