Dimeric thrombopoietin peptide mimetics binding to MP1 receptor and having thrombopoietic activity

A technology of receptor binding and compounds, applied in the field of compounds, can solve problems such as lack of sequence homology
CN1810832AInactive Publication Date: 2006-08-02AMGEN K A INC
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
AMGEN K A INC
Publication Date
2006-08-02
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to the field of compounds, especially peptides or polypeptides, that have thrombopoietic activity. The peptides and polypeptides of the invention may be used to increase platelets or platelet precursors (e.g., megakaryocytes) in a mammal.
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Description

[0001] This application is a divisional application of Chinese patent application 99812517.2 "Mimetic dimer thrombopoietin peptide that binds to MP1 receptor and has platelet production activity" on October 22, 1999.

[0002] This application claims priority from U.S. Provisional Application 06 / 105 348 filed on October 23, 1998. Technical field

[0003] Basically, the present invention relates to the field of compounds, especially peptides or polypeptides with thrombopoietic activity. The peptide or polypeptide of the present invention can be used in mammals to increase the production of platelets or platelet precursors (such as megakaryocytes). Background technique

[0004] The present invention relates to the field of compounds, especially peptides that have the ability to stimulate the production of platelets and their precursor cells such as megakaryocytes in vitro and in vivo. Before discussing the properties of the compounds of the present invention, two proteins with platel...

Claims

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