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Jinganmin medicinal preparation and its preparation method

A pharmaceutical preparation and Jinsensing technology, which is applied in the field of Jinsensing pharmaceutical preparations and its preparation, can solve the problems of slow action and unsatisfactory therapeutic effect of Jinsensing Capsules, etc.

Inactive Publication Date: 2006-08-30
博安兄弟制药(中国)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The compound preparation of traditional Chinese and western medicine is used for antipyretic and analgesic, which can overcome the shortcomings of slow action of traditional Chinese medicine and unstable antipyretic effect of western medicine, and take the best of the two to achieve the elimination of superficial heat, clearing of internal heat, clearing symptoms, rapid action, and antipyretic effect. The therapeutic purpose of thermal stability and synergistic effect should have a good clinical therapeutic effect; but in the clinical application process, the researchers of the present invention found that the therapeutic effect of Jinsensing Capsules is not very ideal

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] Prescription: 250g aspirin, 100g amantadine hydrochloride, 15g caffeine, 2g chlorpheniramine, 10g artificial bezoar, 500g honeysuckle extract, 500g Daqingye;

[0067] Take the honeysuckle medicinal material, coarse powder, add 4 times the amount of 70% hydrochloric acid ethanol solution with a pH of 3 and soak for half an hour, put it into an ultrasonic extraction tank, and perform ultrasonic vibration extraction for 20 minutes at an oscillation frequency of 30kHz, extract twice, and combine Extract the liquid, filter it, and recover the ethanol from the filtrate under reduced pressure at 50°C, dry, and crush to obtain the honeysuckle extract; take Daqingye medicinal material, coarse powder, add 5 times the amount of 80% ethanol to reflux and extract twice, each time for 1 hour , combine the extracts, filter, and recover ethanol from the filtrate under reduced pressure, dry and pulverize to obtain the Folium Folium extract;

[0068] Honeysuckle extract, Folium Folium ex...

Embodiment 2

[0070] Prescription: 250g aspirin, 100g amantadine hydrochloride, 15g caffeine, 2g chlorpheniramine, 10g artificial bezoar, 500g honeysuckle, 500g Daqingye;

[0071] Take the honeysuckle medicinal material, coarse powder, add 8 times the amount of 80% hydrochloric acid ethanol solution with pH 4 and soak for half an hour, put it into an ultrasonic extraction tank, and perform ultrasonic vibration extraction for 30 minutes, the oscillation frequency is 40kHz, extract 3 times, and combine Extract the liquid, filter it, and recover ethanol from the filtrate under reduced pressure below 50°C, dry, and crush to obtain the honeysuckle extract; take Daqingye medicinal material, coarse powder, add 8 times the amount of 90% ethanol to reflux and extract twice, each time for 1 hour , combine the extracts, filter, and recover ethanol from the filtrate under reduced pressure, dry and pulverize to obtain the Folium Folium extract;

[0072] Honeysuckle extract, Folium Folium extract are mix...

Embodiment 3

[0074] Prescription: 250g aspirin, 100g amantadine hydrochloride, 15g caffeine, 2g chlorpheniramine, 10g artificial bezoar, 500g honeysuckle extract, 500g Daqingye;

[0075] Take the honeysuckle medicinal material, coarse powder, add 6 times the amount of 75% hydrochloric acid ethanol solution with a pH of 3.5, soak for half an hour, put it into an ultrasonic extraction tank, and carry out ultrasonic vibration extraction for 25 minutes, the oscillation frequency is 35kHz, extract twice, and combine Extract the liquid, filter it, and recover the ethanol from the filtrate under reduced pressure at 50°C, dry and crush to obtain the honeysuckle extract; take Daqingye medicinal material, coarse powder, add 6 times the amount of 85% ethanol to reflux and extract twice, each time for 1 hour , combine the extracts, filter, and recover ethanol from the filtrate under reduced pressure, dry and pulverize to obtain the Folium Folium extract;

[0076] Mix honeysuckle extract, Folium Folium...

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Abstract

A medicine Jinganmin with higher curative effect is prepared from aspirin, verigyt hydrochloride, coffin, chlorpheniramine, artificial bezoar and the extracts of honeysuckle flower and isatis leaf. Its preparing process is also disclosed.

Description

technical field [0001] The invention belongs to the technical field of pharmacy, and in particular relates to a gold-sensitive pharmaceutical preparation and a preparation method thereof. technical background [0002] Jinsensing Capsules (Chinese patent application number is 200410096174.9, the name of the invention is a pharmaceutical composition for treating colds and upper respiratory tract infections, its preparation method and use) is composed of aspirin, amantadine hydrochloride, caffeine, chlorpheniramine , artificial bezoar, honeysuckle, and Folium Folium is a compound preparation of Chinese and Western medicine prepared from raw materials, which has the effect of antipyretic and analgesic. Among them, aspirin, amantadine hydrochloride, caffeine, and chlorpheniramine are western medicines, and the effects of each component complement each other, and the therapeutic effect is clear; artificial bezoar also has a good heat-clearing and detoxifying effect, and is a commo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/355A61K35/413A61K31/616A61K31/13A61K31/522A61K31/4402A61P11/00A61P31/04A61P31/12
Inventor 杨尚华
Owner 博安兄弟制药(中国)有限公司
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