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Chinese medicinal preparation for treating atrophic arthritis

A technology of traditional Chinese medicine preparations and arthritis, which is applied in the direction of anti-inflammatory agents, non-central analgesics, medical preparations containing active ingredients, etc. It can solve the problems of insufficient understanding of the pathogenesis of damp-heat, toxin and blood stasis, and unsatisfactory therapeutic effects. Achieve non-toxic side effects, easy to take, and improve the effect of joint symptoms

Inactive Publication Date: 2006-08-30
周娅 +3
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, judging from the clinical literature in recent years, the understanding of this disease is mostly focused on wind, cold, dampness and blood stasis, and the pathogenesis of dampness, heat, toxin and blood stasis in the active stage is insufficient, and the treatment effect is not ideal.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Example 1. Take 30g of Qingfengteng, 15g of red rattan, 20g of honeysuckle, 20g of red peony, 30g of white peony, 10g of Gentiana, 20g of Smilax, 30g of Coix seed, 10g of Clematis, 6g of dried ginger and 10g of Picheng tomato, and decoct them in water. One dose per day, 2 months as a course of treatment. It is effective in the treatment of rheumatoid arthritis.

Embodiment 2

[0033] Example 2. Take 15g of Qingfengteng, 10g of red rattan, 15g of honeysuckle, 15g of red peony, 15g of white peony, 10g of Gentiana, 30g of Smilax, 20g of Coix seed, 15g of Clematis, 10g of dried ginger and 6g of Picheng tomato, decoct in water and take. One dose per day, 2 months as a course of treatment. It is effective in the treatment of rheumatoid arthritis.

[0034] Clinical Trials:

[0035] For verifying the therapeutic effect of the present invention, in 2002-2005, the present invention has been carried out following clinical trial in Liaocheng People's Hospital, Shandong Province:

[0036] 1. Materials and methods

[0037] 1.1 Diagnostic criteria

[0038] 1.1.1 Western medicine diagnostic criteria

[0039] Refer to the diagnostic criteria revised by the American Rheumatology Association (ARA) in 1987: ①Morning stiffness for at least 1 hour (>6 weeks); ②Swelling of 3 or more joints (>6 weeks); ③Wrist, metacarpophalangeal Swollen joints or proximal fingertip ...

example 1

[0106]Example 1. Zhu Moumou, female, 56 years old, came to Liaocheng People's Hospital on April 21, 2004 for treatment due to multiple joint swelling and pain in limbs for 6 months. Symptoms include swelling and pain in shoulder joints, some interphalangeal joints, and knee joints, burning sensation in the pain, difficulty in holding hands firmly, difficulty in squatting and walking. Less appetite, fullness in the epigastric cavity, and normal bowel movements. Body of the tongue is red, thick and greasy yellow coating, stringy and rapid pulse. Physical examination: the interphalangeal joints of the index finger and middle finger of both hands, and both wrist joints were swollen, tenderness grade 3, swelling grade 2, and skin temperature was high. The movement of the left knee joint was limited, and the floating patella sign (+). The grip strength of both hands is 12KPa / Hg, and the joint function is grade II. 20-meter walk time: 29 seconds. Laboratory tests and inspections:...

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PUM

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Abstract

A Chinese medicine for treating rheumatoid arthritis is prepared from 11 Chinese-medicinal materials including honeysuckle flower, red peony root, China root, coix seed, etc.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine preparation made of pure Chinese medicines for treating rheumatoid arthritis. Background technique [0002] Rheumatoid arthritis is a common chronic, inflammatory, systemic autoimmune disease, and its prevalence rate ranks first among autoimmune connective tissue diseases. The disease has a high morbidity rate, and the main clinical manifestations are symmetrical and progressive polyarthritis, pain, swelling, and functional decline in the affected joints, and the lesions are continuous and recurrent. The pathological manifestations are chronic inflammation of the synovial membrane, which invades articular cartilage, subchondral bone, ligaments and tendons, etc., eventually leading to bone erosion, joint deformity and loss of function. The etiology and pathogenesis of the disease is still unclear in modern medicine, and non-steroidal ant...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P29/00A61P19/02
Inventor 周娅张梅红樊敏华董风仙
Owner 周娅
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