Composite collagen gel

A technology of collagen and original protein, applied in the field of medical medicine

Inactive Publication Date: 2007-03-14
佟刚
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Collagen in the composite collagen gel has a slow-release effect of drugs, so that antibiotics can be released slowly, making the antibacterial effect more durable, and there is no similar product on the market at present

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] The components of the composite collagen gel and the weight ratio of each component are: in every gram of composite collagen gel

[0018] Collagen 4mg

[0019] Antibiotic Ofloxacin 30mg

[0020] Medical preservative 0.2mg

[0021] Thickener Tragacanth Gum 30mg

[0022] The rest is distilled water

[0023] The composite collagen gel of the present embodiment is through following test:

[0024] Composite collagen gel treatment of bedsores, wounds, skin ulcers, dry skin, itching, and hyperkeratosis in 20 cases; including 13 male patients and 7 female patients; aged 8-75 years, the observation time was 18 months ;Among them, 4 cases of decubitus, 5 cases of trauma, 5 cases of burns (2 cases of hydrothermal burn, 1 case of flame burn, 1 case of chemical burn, and 1 case of electric spark burn), 2 cases of ulcer, 1 case of dry skin, and 2 cases of itching , 1 case of hyperkeratosis.

Embodiment 2

[0026] The components of the composite collagen gel and the weight ratio of each component are: in every gram of composite collagen gel

[0027] Collagen 5mg

[0028] Antibiotic Ofloxacin 40mg

[0029] Medical preservative 0.2mg

[0030] Thickener Tragacanth Gum 50mg

[0031] The rest is distilled water

[0032] The composite collagen gel of the present embodiment is through following test:

[0033] Composite collagen gel treatment of bedsores, wounds, skin ulcers, dry skin, itching, and hyperkeratosis in 20 cases; including 13 male patients and 7 female patients; aged 8-75 years, the observation time was 18 months ;Among them, 4 cases of decubitus, 5 cases of trauma, 5 cases of burns (2 cases of hydrothermal burn, 1 case of flame burn, 1 case of chemical burn, and 1 case of electric spark burn), 2 cases of ulcer, 1 case of dry skin, and 2 cases of itching , 1 case of hyperkeratosis.

Embodiment 3

[0035] The weight ratio of described composite collagen gel component and each component is: in every gram composite collagen gel contains

[0036] Collagen 6mg

[0037] Antibiotic Ofloxacin 50mg

[0038] Medical preservative 0.3mg

[0039] Thickener Tragacanth Gum 70mg

[0040] The rest is distilled water

[0041] The composite collagen gel of the present embodiment is through following test:

[0042] Composite collagen gel treatment of bedsores, wounds, skin ulcers, dry skin, itching, and hyperkeratosis in 20 cases; including 12 male patients and 8 female patients; aged 8-75 years, the observation time was 18 months ;Among them, 4 cases of decubitus, 6 cases of trauma, 4 cases of burns (4 cases of hydrothermal burns, 1 case of flame burns, 1 case of chemical burns, and 1 case of electric spark burns), 1 case of ulcers, 2 cases of dry skin, and 1 case of itching , 2 cases of hyperkeratosis.

[0043] To sum up, among the 60 patients who were applied, except for the patie...

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PUM

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Abstract

The invention relates to a kind of compound collagen gel, which is the mixture of collagen and antibiotics. For every gram gel, there is 1-100mg collagen, which is extracted from tendon of the rat tails, swine, or ox, 1-100mg antibiotics, 0.1-1.0mg medical antiseptics, 10-500mg thickening agents, and water. The antibiotics and collagen act cooperatively to be used in the treatment of the following diseases: different kinds of open wound, anabrosis caused by diabetes, skin damage because of venereal disease, hyperkeratesis, cuticularized skin problems such as keratosis palmaris ET plantaris, winter cutitis and ichthyosis. Since the collagen protein in the gel can be easily absorbed to provide threpsis to the diseased region, so it can promote the agglutination very effectively as well as extend the time of releasing time of the antibiotics.

Description

technical field [0001] The present invention relates to medical drugs. Background technique [0002] The composite collagen gel made of collagen as raw material and adding appropriate amount of antibiotics, thickeners, etc., is used in external medical drugs for wounds. It has the characteristics of promoting wound healing, antibacterial and anti-inflammatory, and long-lasting medicinal properties. The film formed by the wound has good air permeability. The collagen in the composite collagen gel has a slow-release effect of drugs, so that the antibiotics can be released slowly, making the antibacterial effect more durable, and there is no similar product on the market at present. Contents of the invention [0003] The purpose of the present invention is to provide a composite collagen gel, which contains antibiotics and collagen components, and is suitable for various types of open wounds, chronic wounds with infection caused by various diseases, such as bedsores, arterio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/39A61K45/06A61K31/5383A61K9/00A61P17/02
Inventor 佟刚
Owner 佟刚
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