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Isodon lophanthoides extract and its prepn process and application

A technology for extracting fragrant tea leaves, which is applied in the field of extracts of fragrant tea leaves with narrow baselines, can solve the problems of low yield of extracts, unsatisfactory protective effects of drugs on immune liver damage, increased bile excretion, etc., to achieve Regulate immune function, inhibit virus replication and release of inflammatory mediators, and reduce free radical damage

Inactive Publication Date: 2007-03-21
GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

Although the extract has the effects of inhibiting the replication of hepatitis B virus, protecting immune liver damage, improving cellular immunity, increasing the weight of spleen and thymus in immunocompromised experimental animals, and increasing bile excretion, the yield of the extract is low, and its protection Suboptimal drug activity in immune liver injury

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0088] Take 20kg of dried fragrant tea with narrow baseline pattern, ultrafinely pulverize it into a powder of more than 10 meshes, add 3 times of water and soak at room temperature for 1.5 hours, and then extract with a high-pressure differential continuous extractor with a pressure of 10 MPa. The extract was concentrated in vacuo to 1 times the volume.

example 2

[0090] Take 20kg of dried fragrant tea with narrow baseline pattern, ultrafinely pulverize it into a powder of more than 20 meshes, add 10 times of water and soak at room temperature for 1.5 hours, then extract with a high-pressure differential continuous extractor, the pressure is 10 MPa, and the extract is separated from the solid and liquid by the membrane Concentrate and dry at room temperature into a solid of 3.26kg.

example 3

[0092] Take 20kg of dried fragrant tea with narrow baseline pattern, ultrafinely pulverize it into a powder of more than 100 mesh, add 10 times of water and soak it at room temperature for 1.5 hours, then extract it with a high pressure differential continuous extractor, the pressure is 10 MPa, and the extract is concentrated to 1 Double the volume, vacuum-dried to a solid of 3.40kg.

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PUM

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Abstract

The present invention provides one kind of Isodon lophanthoides extract. The Isodon lophanthoides extract is prepared through crushing Isodon lophanthoides to powder finer than 10 mesh, adding water of over 3 times, extracting at 10-60 MPa pressure and concentrating. The extract may be used in preparing various clinically acceptable orally taken preparations for treating hepatitis B, immunologic hepatitis, alcoholic hepatitis and hepatic fibrosis. The extracting process with ultrafine grinding and high pressure extracting has high extracting rate of the effective components in Isodon lophanthoides, so that the extract has high treating effect.

Description

technical field [0001] The invention relates to a Chinese herbal medicine extract, in particular to a narrow base line grain fragrant tea extract. Background technique [0002] Narrow base line pattern Xiangchacai is a plant of the genus Xiangchacai, a kind of Xihuangcao, which is mainly produced in Guangdong area. It has the functions of clearing away heat and dampness, reducing jaundice, cooling blood and dissipating blood stasis; It has a significant curative effect on icteric hepatitis and acute cholecystitis. [0003] On March 26, 2003, the State Intellectual Property Office published an invention patent application for "a natural medicine Xihuangcao extract for the treatment of hepatitis" (the publication number is CN1405177). The application uses three extraction processes - alcohol Extraction method, water extraction method and supercritical carbon dioxide fluid extraction method to extract a kind of antiviral active ingredients containing 2-hydroxyursolic acid, 2,3...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/53A61K9/16A61K9/20A61K9/48A61P1/16A61P31/14A61P31/20
Inventor 赖小平胡英杰朱宇同刘中秋陈建南侯少贞
Owner GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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