Monitoring variation patterns in physiological parameters associated with myocardial instability
a myocardial instability and physiological parameter technology, applied in the field of monitoring myocardial instability, can solve the problems of limiting the use of comprehensive algorithms that exceed the capability of devices, difficult and imperfect task of accurately predicting the onset of sudden cardiac death,
Inactive Publication Date: 2010-06-24
PACESETTER INC
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[0005]In one embodiment, a method of analyzing myocardial instability is provided. The method includes obtaining a physiological parameter representative of myocardial behavior over a set of cardiac cycles and determining reversal points in the physiological parameter over the set of cardiac cycles. The method also includes identifying myocardial instability based on the reversal points in the physiological parameter. A reversal point may correspond to
Problems solved by technology
Yet, in spite of the known risk stratification methods, accurate prediction of the onset of sudden cardiac death remains a relatively difficult and imperfect task.
Additionally, the known implantable devices hardware may limit the usage of comprehensive algorithms that exceed device capability.
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[0020]In the following detailed description, reference is made to the accompanying drawings which form a part hereof, and in which are shown by way of illustration specific embodiments in which the present invention may be practiced. These embodiments, which are also referred to herein as “examples,” are described in sufficient detail to enable those skilled in the art to practice the invention. It is to be understood that the embodiments may be combined or that other embodiments may be utilized, and that structural, logical, and electrical variations may be made without departing from the scope of the present invention. For example, embodiments may be used with a pacemaker, a cardioverter, a defibrillator, and the like. The following detailed description is, therefore, not to be taken in a limiting sense, and the scope of the present invention is defined by the appended claims and their equivalents. In this document, the terms “a” or “an” are used, as is common in patent documents,...
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A method of analyzing myocardial instability includes obtaining a physiological parameter representative of myocardial behavior over a set of cardiac cycles and determining reversal points in the physiological parameter over the set of cardiac cycles. The method also includes identifying myocardial instability based on the reversal points in the physiological parameter. A reversal point may correspond to a value of the physiological parameter, during a current cardiac cycle, that exceeds or is less than the values of the physiological parameter during prior and subsequent cardiac cycles. Optionally, the method includes calculating differences between values of the physiological parameter for consecutive cardiac cycles and detecting the reversal points when a current difference exceeds or is less than differences for prior and subsequent cardiac cycles.
Description
FIELD OF THE INVENTION[0001]Embodiments of the present invention pertain generally to implantable and external medical devices, and more particularly pertain to methods and systems that monitor myocardial instability.BACKGROUND OF THE INVENTION[0002]Sudden cardiac death (SCD) is the major cause of cardiac mortality and affects over 400,000 individuals per year in the United States. SCD often occurs in patients with coronary artery disease, cardiomyopathy, and ion channelopathies. SCD may be caused by a ventricular tachyarrhythmia that degenerates into ventricular fibrillation. Less commonly, bradyarrhythmias are associated as the initiating event of sudden cardiac death.[0003]Many patients at risk of sudden cardiac death have pacemakers, implantable cardioverter defibrillators (ICDs) or other medical devices implanted therein. These devices may continuously obtain cardiac signals that are digitized and presented as electrocardiograms (ECG). ECGs are composed of various waves and seg...
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Login to View More IPC IPC(8): A61B5/0452
CPCA61B5/0006A61N1/365A61B5/0452A61B5/0031A61B5/349
Inventor QU, FUJIAN
Owner PACESETTER INC