30 results about "Gramine" patented technology

A polishing composition which achieves surfaces with high planarity and the reduction of corrosions in the wiring metal surface at the same time is provided.

Such compositions include

• • (A) an oxidizing agent;
  • (B) at least one acid selected from an amino acid, a carboxylic acid of no more than 8 carbon atoms, and an inorganic acid;
  • (C) a sulfonic acid having a concentration of 0.01% by mass or more and having an alkyl group of 8 or more carbon atoms;
  • (D) a fatty acid having a concentration of 0.001% by mass or more and having an alkyl group of 8 or more carbon atoms; and
  • (E) at least one compound selected from a pyridine carbonyl compound, a nonionic water-soluble polymer, 2-pyrrolidone, N-methylpyrrolidone, 1,3-dimethyl-2-imidazolidinone, gramine, adenine, N,N′-diisopropylethylenediamine, N,N′-bis(2-hydroxyethyl)ethylenediamine, N,N′-dibenzylethylenediamine, and N,N′-diphenylethylenediamine.

The invention belongs to the field of antiviral drugs. The invention provides applications of Gramine and derivatives thereof to preparation of medicaments for resisting adenovirus Type 7. Gramine derivatives are compounds shown in G1,G2,G3,G4,G5,G10,G17,G18,G19,G20, and G21. Experiments for researching activity of Gramine derivatives for resisting ADV7, pharmacology research of Gramine derivatives for resisting ADV7, and tests of inhibition effects of G19 for ADV7 duplication show that Gramine derivatives can inhibit cytopathic effects (CPE) generated by ADV7 on host cell Hela, enhance cell survival rate, inhibit yield of progeny virus, and mainly inhibit the duplication phase of ADV7 virus in host cells. The Gramine and derivatives thereof have potential for preparing anti-ADV1 virus medicaments, and the compounds have the advantages of simple synthesis process, and economy and fastness; the compounds are easy for large-scale production, and have clinic application prospects.

The invention relates to a formula (I) compound containing the structural formula (refer to the Specification), in the formula, X1 refers to H and Cl; X2 refers to H, Cl and Br; R refers to CH3, CH2CH3, CH2(CH3)2, CH2CH2CH2CH3 and CH2CH2CH2CH2CH2CH(CH3)2. The invention also relates to a preparation method for the formula (I) compound and an acyclic acid zinc/copper resin adopting the compound as a comonomer, and the invention further relates to application of the resin compound in marine antifouling paint. According to the formula (I) structure, the acyclic acid zinc/copper resin adopting an ester derivative containing acrylamide indole as the comonomer has a relatively good self-polishing property, can slowly release an antifouling gramine derived structure and can effectively prevent adhesion of marine fouling organisms.

The invention discloses an efficient antifouling paint for a fishing gear. The antifouling paint is prepared from the following components: methyl methacrylate, vinyltriethoxysilane, butyl acrylate, methyl silicone resin, gramine, epoxy menadione, zinc pyrithione, rosin, nano titanium dioxide, nano zinc oxide, dioctyl phthalate, an initiator and an emulsifier. The antifouling paint for the fishing gear, disclosed by the invention, has the advantages of low toxicity, high efficiency, conformity to environmental protection requirement, high stability, convenience in use, simplicity in application, high cost performance, good adhesion and good antifouling property; through modifying treatment on nano titanium dioxide, the dispersity and stability can be improved while the hydrophobicity is enhanced; by mixing methyl methacrylate and vinyltriethoxysilane through the modified nano titanium dioxide, the ocean antifouling comprehensive performance of the antifouling paint disclosed by the invention is remarkably improved, and the bio-attachment resistance is enhanced; and moreover, the antifouling paint has good surface property, water resistance and mechanical property.

The present invention relates to synthesis of intermediate for polypeptide antibiotic and immunosuppressor, and is especially synthesis process of D-tryptophane. The synthesis process includes the following steps: reaction of N-acetyl diethyl malonate and gramine in the molar ratio of 1 to 1-2 at 78-110 deg.c under alkaline condition inside solvent for 5-10h; reaction of the product and alkali solution at 60-90 deg.c under nitrogen protection for 6-10 hr, decompression distilling to eliminate solvent, ethyl acetate extraction, regulating water layer pH to lower than 3 with hydrochloric acid, filtering and vacuum drying; dissolving the product in ethanol through heating, adding resolving agent, reaction at 25-60 deg.c under nitrogen protection for 3-8 hr, filtering precipitate, water washing, reacting with dilute hydrochloric acid solution, adding alkali solution to react, regulating pH to below 6.5, with glacial acetic acid, cooling, filtering, stoving, etc.

The invention discloses cage antifouling paint for mariculture. The paint is prepared from butyl acrylate, methyl silicone resin, gramine, rosin, nano-zinc oxide, dioctyl phthalate and an initiator. The cage antifouling paint has the advantages of low toxicity, high efficiency, strong stability, convenience in use, simple application, high cost performance, good adhesion and good antifouling performance, and accords with the environment-friendly requirement. According to the cage antifouling paint, butyl acrylate and methyl silicone resin are premixed, the mixture is modified by adopting hydroxyl silicone oil, and the mixture is mixed and ground with bentonite, so that the structure tissue performance of the paint is greatly improved, the compatibility of the paint with other ingredients can be promoted, and the service life of the paint is prolonged; and rosin and zinc oxide are premixed, the cohesion of rosin is improved, and the film forming performance of the paint is enhanced.

The invention discloses a dispersible oil suspending agent containing triafamone and cyhalofop-butyl. The dispersible oil suspending agent is prepared from 5 to 10% by mass of triafamone, 8 to 10% by mass of cyhalofop-butyl, 3 to 6% by mass of eucalyptus oil, 2 to 4% by mass of gramine, 11 to 13% by mass of an emulsifier, 1 to 2% by mass of a dispersant, 0.5 to 1% by mass of a stabilizer, 0.5 to 1% by mass of a synergist, 10 to 20% by mass of an organic solvent and the balance of methyl oleate. The dispersible oil suspending agent containing triafamone and cyhalofop-butyl has significant synergistic or additive effects. Compared with a single agent, the composition improves the herbicidal effects. Through use of a plant weeding ingredient in the formula, a use amount of pesticide is reduced, a cost is reduced and environmental pollution is reduced.

The invention relates to an efficient cultivation method for rhizoma acori gramine. The method comprises the following steps: 1) constructing a nutrient tank; 2) carrying out transplanting culture; 3)carrying out top dressing; and 4) carrying out field management. According to the method, raw materials are taken from local resources, and the culture of planting nutritional soil is carried out bymainly using silt of a silt basin, so that the treatment on sludge and sewage by plant cultivation is achieved, a sufficient nutrient guarantee is provided for growth of acorus gramineus through changing wastes into valuables, and the effect of killing two birds with one stone is achieved. The survival rate of the acorus gramineus planted by the cultivation method disclosed by the invention reaches 95% or more, and the yield and effective ingredient content are high, so that some problems of the existing artificial planting of the acorus gramineus are solved, and the method is applicable to large-scale popularized planting.

The invention relates to a compound having a structure formula (I) shown in the specification, wherein in the formula, X1 is H, Cl or Br, and X2 is H or Cl. The invention also relates to a preparation method of the compound in the formula (I), and zinc acrylate/copper resin obtained by taking the compound as a comonomer, and further relates to use of the resin as a marine antifouling material. The zinc acrylate/copper resin obtained by taking the amide derivative having the structure shown in the general formula (I) and containing double-bond gramine as the comonomer has good self-polishing property in sea water, and a gramine-derived structure with an antifouling function can be slowly released, so that adhesion of marine fouling organisms is effectively prevented.

The invention discloses a traditional Chinese and Western medicine composition for treating upper respiratory tract infection. The traditional Chinese and Western medicine composition for treating the upper respiratory tract infection is prepared from the following main raw materials in parts by weight: 20 to 30 parts of trifloroside, 10 to 15 parts of aspirin, 5 to 13 parts of beta-acetoxyisovalerylalkannin, 8 to 14 parts of cefathiamidine, 27 to 35 parts of Chinese ephedra herb, 6 to 8 parts of radix scutellariae B, 4 to 9 parts of fructus aristolochiae E, 16 to 19 parts of herba menthae, 2 to 6 parts of gramine and 2 to 6 parts of pinoresinol diglucoside. According to the medicine disclosed by the invention, raw material components are strictly selected according to a know mechanism on the upper respiratory tract infection and the comprehensive rehabilitation aim is realized; the traditional Chinese and Western medicine composition has the characteristics of rapid effect, stable effect, convenience for carrying and orally taking and no toxic side effect after the traditional Chinese and Western medicine composition is orally taken for a long period.

The invention discloses a method for preparing a mosquito repellent. The method comprises the following steps: weighing artemisia argyi, lonicera japonica, rhizoma acori gramine, mosquito-repelling herbs and herba menthae, adding water according to a ratio of 3:5:4:3, carrying out distilling off, and collecting aqua aromatica; subjecting the collected aqua aromatica to redistillation; adding polysorbate, and carrying out uniform mixing; carrying out filtering, and collecting liquid medicine and dregs; decocting the dregs at least twice by adding water to the dregs, and carrying out filtering,so as to obtain a decoction; merging the decoction and the liquid medicine, and concentrating the filter liquor until clear paste is obtained; adding ethanol, carrying out standing, then, taking supernatant, and recovering the ethanol until no alcohol flavor is absent; adding benzoic acid, carrying out boiling, adding the aqua aromatica, and carrying out uniform mixing; adding pure water for dilution, and carrying out sterilizing, thereby obtaining the mosquito repellent. The mosquito repellent prepared by the method is free of an alcohol flavor, low in irritation, low in preparation cost, long in mosquito-repelling time and good in effect, and meanwhile, an affected part bitten by mosquitoes can be subjected to inflammation diminishing and itching relieving rapidly.

The invention discloses a fishing net anti-fouling agent. The anti-fouling agent is prepared from the following components in parts by weight: hydroxyl silicone oil, chlorothalonil, epoxy resin coating, gramine, sulfanilamide, nanometer aluminum oxide, gamma-aminopropyltriethoxysilane, an initiator and a film-forming agent. The treated epoxy resin coating is used as a carrier, so that the manufactured fishing net anti-fouling agent has strong adhesive force, can be well bonded with a net, has good water resistance and has certain flexibility and toughness. The fishing net treated by the anti-fouling agent has a remarkable capability for inhibiting and killing algae, moss, serpulidae, mussel and other adhesion organisms, manual regular net washing or new net changing is avoided, and thus massive cost and labor force can be saved; and the home-made film-forming agent is bonded with the epoxy resin coating, the anti-fouling agent has excellent water resistance and abrasion resistance, and the coated bio-resistant drugs cannot drained into water, so that the water body is prevented from being polluted, the drug efficacy of the treated fishing net can not be lost in a short time, and the service life of the anti-fouling agent is prolonged.

The invention discloses a facial-beautifying freckle-removing nursing product containing traditional Chinese medicine ingredients and a preparation method for the facial-beautifying freckle-removing nursing product. The facial-beautifying freckle-removing nursing product comprises the following raw materials: radix ginseng, radix ampelopsis, rhizoma bletillae, radix notoginseng, pearls, cassia twigs, royal jelly, taraxacum mongolicum, peach blossoms, rhizoma acori gramine, poria cocos, cortex phellodendri, horse oil, vitamin C, rhizoma chuanxiong, cordyceps sinensis, radix glycyrrhizae, fructus tribuli, opuntia dillenii, white lilac, ehodiola rosea, herba ecliptae, purple perilla, ginger and deionized water. According to the facial-beautifying freckle-removing nursing product and the preparation method therefor, the facial-beautifying freckle-removing nursing product is prepared by selecting natural traditional Chinese medicines and combining a modern traditional Chinese medicine skin-care facial-beautifying theory; and through a synergistic action of all the ingredients, the obtained facial-beautifying freckle-removing nursing product not only has the treatment effects of relieving itching, resisting bacteria and resisting allergy, but also can be used for promoting blood circulation of capillary vessels in skin, improving nutrient supply of the skin and reducing cornificationand pigmentation of the skin, thereby achieving facial-beautifying, freckle-removing, moisture-preserving and crease-resisting effects. In addition, all the raw materials are purely-natural ingredients, so that the facial-beautifying freckle-removing nursing product has the characteristics of low skin irritation, safety and reliability and cannot cause any side effect on the skin.

The invention discloses a formula of a medicine package for a healthcare pillow. The medicine package has the total mass of 1000g and is prepared from the following raw materials by weight: 70g of herba menthae, 70g of rhizoma acori gramine, 100g of flower buds of lily magnolia, 100g of folium artemisiae argyi, 100g of Chuanxiong rhizomes, 300g of cassia seeds and 260g of buckwheat husks. Through arranging 70g of herba menthae, 70g of rhizoma acori gramine, 100g of flower buds of lily magnolia, 100g of folium artemisiae argyi, 100g of Chuanxiong rhizomes, 300g of cassia seeds and 260g of buckwheat husks in the medicine package, Insomnia and dreaminess can be treated effectively, and thus, the formula has a very good treatment effect on the insomnia and is very beneficial to human health.

The invention belongs to the technical field of drug, and particularly relates to gramine derivative (1-2), a drug combination thereof, a preparation method thereof, application of the derivative or the drug combination serving as a melatonin and 5-serotonin receptor agonist, application of the derivative or the drug combination to the preparation of drugs resisting mental diseases, and particularly application of the derivative or the drug combination to the preparation of drugs for treating and improving central nervous system diseases related to melatonin and 5-serotonin receptor.

The invention discloses a mosquito-repellent box. The mosquito-repellent box is prepared from the following raw materials in parts by weight (gram): 30-55 parts of folium artemisiae argyi, 2-4 parts of rhizoma acori gramine, 1-2 parts of lonicera japonica, 3-8 parts of cloves, 3-12 parts of radix angelicae, 2-10 parts of perilla leaves, 2-4 parts of herba menthae, 2-5 parts of herba agastachis, 2-4 parts of perilla stems, 2-4 parts of rhizoma kaempferiae, 2-3 parts of borneol, 1-3 parts of lavandula angustifolia, 2-3 parts of murraya paniculata, 2-3 parts of rhizoma atractylodis and 1-3 partsof glossogyne tenuifolia. The mosquito-repellent box is prepared from purely-natural Chinese herbal medicines and has no need of ignition, and thus, potential safety hazards are eliminated; and the mosquito-repellent box is faint-fragrant, moderate and non-pungent in odor, is free of toxic or side effects and is applicable to children.