35 results about "O-Methoxyphenol" patented technology

The invention discloses a rapid detection method of forbidden azo dyes in dyed textiles, which uses the following reagents: 1) an extracting reagent A: 10 mL of methyl ten-butyl ether; 2) an extracting reagent B: 5 mL of 0.1-1.0 mol / L hydrochloric acid solution; 3) a reagent 1: 0.05 mL of 50 g / L NaNO2 solution; 4) a reagent 2: 0.5 mL of 25 g / L NH4SO3NH2 solution; 5) a reagent 3: 1 mL of o-metoxyphenol ethanol aqueous solution with volume percentage concentration of 2%; 6) a reagent 4: 1 mL of 0.5 mol / L NaOH solution; 7) a reducing agent 1: 16 mL of 0.06 mol / L citrate buffering solution with pH of 6.0; and 8) a reducing agent 2: 3.0 mL of 200 mg / L sodium hydrosulfite solution. According to the invention, the pre-treatment is realized by liquid-liquid extraction of textile reduction solution and discoloring, and the aromatic amine is measured by coloration; the pre-treatment is simple and rapid enough to greatly simplify the original steps, and no instrument or equipment is necessary in the measurement so as to realize the quick screening detection of forbidden azo dyes in textiles.

The synthesis process of amide derivative includes the reaction between N-methylol fatty amide with the structure of RCONHCH2OH and benzene substitute in the presence of catalyst and inside ethanol or aceitc acid and the separation purify reaction product. The process features the catalyst being H-type strong acid cationic exchange resin, which is the copolymer of sulfonated coal and sulfonated styrene or sulfonated phenolic resin; the benzene substitute being resorcin, catechol, o-methoxyphenol, m-methoxyphenol, veratrole, m-dimethoxyl benzene, o-ethoxyphenol, m-ethoxyphenol, o-diethoxyphenol or m-diethoxyphenol; and introduction of nitrogen during synthesis. The present invention has advantages of no corrosion of strong acid and the reuse of unreacted material after filtering.

This invention relates to a method for synthesizing ranolazine drug for treating stenocardia. The method comprises: performing amidation and N-monoalkylation on 2, 6-dimethylaniline to obtain N-(2, 6-xylyl)-2-(1-piperazine) acetamide, and then reacting with 2-(2-methoxyphenoxy) epoxyethane generated from o-methoxyphenol and epoxy chloropropane to obtain anolazine. The reactions include the refinery of 2-chloro-N-(2,6-xylyl)acetamide by cyclohexane and the recrystallization of ranolazine by ethanol / ethyl acetate (2:1), thus can raise the yield.

The invention discloses a preparation technology and a refining method of ranolazine, which are more suitable for industrial production. The method comprises the following concrete steps: using 2, 6-dimethylaniline and methylpyrocatechine as original materials; sequentially carrying out four reaction processes of N-acylation, O-alkylation, N-alkylation and N-alkylation to synthesize ranolazine; and then, recrystallizing to obtain a refined product. The refined product obtained by the method has high purity, and the method also has the advantages of simple operation, low production cost and high yield and is more suitable for industrial production.

The invention discloses a method for preparing catechol from lignin, which comprises the following steps: after mixing alkali lignin and a solution, adding the mixture into a high-pressure reaction kettle, and reacting in an inert gas atmosphere to generate guaiacol; and hydrolyzing the guaiacol to obtain the catechol. The invention overcomes the defect of low selectivity in the prior art, solves the problem that the raw material phenol is derived from non-renewable fossil fuels, and provides a method for preparing catechol from the reactant guaiacol prepared by degrading lignin, which is often used as waste in renewable biomass.

The invention relates to a liquid chemical fertilizer synergism additive. 0-20 percent of 2,4- dinitrophenol, 0-20 percent of a-naphthylacetic acid, 0-20 percent of indoleacetic acid, 0-20 percent of indolebutyric acid, 0-30 percent of o-nitrophenol, 0-30 percent of p-nitrophenol, 0-20 percent of 5- nitro guaiacol, 0-20 percent of guaiacol, 0-10 percent of brilliant blue, 0-10 percent of polyoxyethylene ethers surfactant and 0-70 percent of methanol according to the weight content are mixed and stirred to produce the liquid chemical fertilizer synergism additive. The fertilizer synergism additive overcomes the shortages of the existing chemical fertilizers, improves chemical fertilizer utilization ratio, reduces chemical fertilizer application and pollution to the environment, has obvious synergism effect, reaches the purpose of increasing production and efficiency, environmental protective and reducing cost, therefore, the popularization of the liquid chemical fertilizer synergism additive has significant social meaning in China as a big agricultural Country.

The invention provides a high-activity nickel phosphide as well as a preparation method and application thereof. The preparation method is characterized in that a high-load-capacity Ni / SiO2-TiO2 catalyst adopting an SiO2-TiO2 compound oxide as a catalyst carrier is prepared according to a coprecipitation method; then a high-activity Ni2P / SiO2-TiO2 catalyst is prepared according to a triphenylphosphine liquid phase phosphating method; nickel phosphide is used as the active component. According to the method, the Ni / SiO2-TiO2 catalyst is pre-reduced to form highly-dispersed nano nickel particlesbefore being phosphatized, so that Ni / SiO2-TiO2 is easily phosphatized by PPh3 in the liquid phase under low temperature, and as a result, the highly-dispersed Ni2P particles can be produced. Test results show that the catalyst is high in activity for o-methoxyphenol and high in selectivity to cyclohexane.

The invention provides a high-load metal nickel catalyst as well as a preparation method and application thereof. The preparation method is characterized in that Ni(NO3)2.6H2O is subjected to co-precipitation with TiCl4-ethyl alcohol solution and Na2SiO3.9H2O, and water is removed under low surface tension of n-butyl alcohol, thus the high-load metal nickel catalyst which adopts SiO2-TiO2 compoundoxide as a carrier and metal nickel as an active component is prepared; the compound oxide contains TiO2, so that the L acid content is increased; moreover, B acid is generated, and as a result, themutual action between the carrier and the metal component is improved; the surface area of the catalyst is enlarged; the temperature for reduction is reduced; the reduction performance and the dispersing performance of metal nickel are improved; the quantity of active nickel sites on the surface is obviously increased; the reduction nickel particles on the SiO2-TiO2 carrier can be minimized to be4 nm under high load. Therefore, the prepared catalyst is high in low-temperature deoxidization activity, and is high in activity for o-methoxyphenol and high in selectivity to cyclohexane.

Belonging to the technical field of stimulating paint for plants, the invention specifically relates to a stimulating paint composed of low doses of microelements and used for rapid synthesis of rubber. The paint is prepared by the steps of: mixing a thickening agent with water, adding ethephon, rare earth molybdenum and sodium 5-nitroguaiacolate, stirring and mixing the mixture uniformly, thus obtaining a finished product. The paint of the invention has the advantages of simple technology and low cost. Ethene is taken as the osmotic agent to make rare earth molybdenum and sodium 5-nitroguaiacolate infiltrate into a rubber tree, so that the rubber tree can be synthesized into rubber rapidly and the cambium of the rubber tree can be promoted to grow rapidly. The paint of the invention is characterized by large range of increase in yield, stable yield, few emergence of dead bark and convenient use.

The invention discloses a method for preparing o-methoxyphenol from lignin. The method comprises the following steps: pre-activating lignin, namely pre-soaking and activating the lignin with alcohol and water sequentially; putting the pre-activated lignin into an autoclave, taking the alcohol and water as mediums, adding solid acid as a catalyst, reacting at 200-240 DEG C for 0.5-1 hour to obtain reaction liquid, filtering, extracting the filtrate, and concentrating the extract to prepare o-methoxyphenol. According to the method, o-methoxyphenol is extracted by using a lignin byproduct derived from forestry and agricultural residues as a raw material by adopting a specific process, is pure, and does not contain other impurity, so that excellent foundation is laid for the application of o-methoxyphenol; and according to the method, the preparation process is simple, the cost is low, and the method has huge application prospect.

The invention relates to a method for synthesizing a drug, and concretely relates to a method for synthesizing berberrubine from catechol. The method comprises the following steps: carrying out a selective methylation reaction on the raw material catechol and 2-chloromethane to obtain o-methoxyphenol, and carrying out a selective formylation reaction to obtain 2-hydroxy-3-methoxybenzaldehyde; carrying out a methylenation reaction on catechol and 2-chloromethane to obtain piperidine, and carrying out a catalytic addition reaction on the piperidine and 2-chloroethylamine to obtain homopiperonylamine; carrying out a one-pot condensation hydrogenation reaction on the homopiperonylamine and 2-hydroxy-3-methoxybenzaldehyde under the action of a nickel-based catalyst, adding hydrochloric acid tothe obtained reaction product, cooling obtained crystals, and performing filtration to obtain a hydrochloride condensate; and refining the hydrochloride condensate, carrying out a cyclization reactionon the refined hydrochloride condensate and glyoxal under the action of a copper-based catalyst, refining the obtained reaction product, adding hydrochloric acid, performing cooling for crystallization, and filtering and washing obtained crystals to obtain the product berberrubine. The method realizes industrial total synthesis of the berberrubine, and opens up a chemical synthesis method for berberrubine drugs.

The invention discloses a peptidergic nitrogen fertilizer and a manufacturing method thereof; the formula of raw materials are as follows: an anionic surface active agent, alkyl sulfonate, alkyl carboxylic salt; 2, 4-dinitrophenol; a-naphthylacetic acid; indoleacetic acid; indolebutyric acid; o-nitrophenol; p-nitrophenol; 5-nitroguaiacol; guaiacol; goomassie and chemical nitrogen. The raw materials are fully mixed, stirred and processed to be bright yellow granular according to a method for processing compound fertilizers. As the peptidergic nitrogen fertilizer overcomes deficiencies of the existing fertilizers and improves the utilization ratio of the fertilizer, the aim of increasing production and efficiency, environmental and reducing the cost is achieved. Our country is a big agricultural country, and the application of the peptidergic nitrogen fertilizer has certain economic benefit and profound social significance.

The present invention relates to chemical fertilizer, which comprises 2, 4-dinitrophenol 0.01-1 wt%, alpha-naphthylacetic acid 0.01-1 wt%, indolacetic acid 0.01-1 wt%, o-nitrophenol 0.01-1 wt%, p-nitrophenol 0.01-1 wt%, 5-nitro methoxyl phenol 0.01-1 wt%, o-methoxyl phenol 0.01-1 wt%, methanol 1-3 wt%, N, N-diethylaminoethanol carproate 0.01-1 wt%, citric acid 0.01-1 wt%, brilliant blue 0-1 wt%, and composite chemical fertilizer 87-98.5 wt%, mixed and pelletized. The chemical fertilizer has raised utilization rate of chemical fertilizer, reduced use amount of chemical fertilizer, lowered cost, obvious yield increasing effect, reduceed environmental pollution and capacity of raising quality of crop.

The invention discloses a rapid detection kit of forbidden azo dyes in dyed textiles, which comprises: 1) an extracting reagent A: 10 mL of methyl ten-butyl ether; 2) an extracting reagent B: 5 mL of 0.1-1.0 mol / L hydrochloric acid solution; 3) a reagent 1: 0.05 mL of 50 g / L NaNO2 solution; 4) a reagent 2: 0.5 mL of 25 g / L NH4SO3NH2 solution; 5) a reagent 3: 1 mL of o-metoxyphenol ethanol aqueous solution with volume percentage concentration of 2%; 6) a reagent 4: 1 mL of 0.5 mol / L NaOH solution; 7) a reducing agent 1: 16 mL of 0.06 mol / L citrate buffering solution with pH of 6.0; and 8) a reducing agent 2: 3.0 mL of 200 mg / L sodium hydrosulfite solution. According to the invention, the pre-treatment is realized by liquid-liquid extraction of textile reduction solution and discoloring, and the aromatic amine is measured by coloration; the pre-treatment is simple and rapid enough to greatly simplify the original steps, and no instrument or equipment is necessary in the measurement so as to realize the quick screening detection of forbidden azo dyes in textiles.

The invention relates to methoxy polyaromatic ether ketone resin and a preparation method thereof. The preparation method comprises the following steps: taking aromatic dihalide, such as 4,4'-difluorobenzophenone or 4,4'-dichlorophenone and 4,4'-dichlorodiphenylsulfone, and o-methoxyphenol as raw materials, and performing nucleophilic substitution reaction to prepare a methoxyaryl ether monomer; and then performing electrophilic substitution polycondensation reaction on the methoxyaryl ether monomer and acryl chloride such as paraphthaloyl chloride or m-phthaloyl chloride to prepare a series of resin with methoxy polyaromatic ether ketone. The resin has high heat resistance, high dissolubility, high film-forming property and excellent mechanical properties, and the methoxy group can be further functionalized.

The invention discloses a sheep manure wrapping technology. The sheep manure wrapping technology comprise the following steps of step 1, adding auxiliary materials into fresh sheep manure, and adjusting the content of dry mater in the mixture to 30 to 35%; step 2, crushing the mixture, adding 6 to 10wt% of special additive, and radiating for 20 to 30min by ultraviolet ray with intensity of 160 to200muW / cm<2>; step 3, mixing with 10 to 15wt% of microorganism fermenting agent, pressing, and packaging with a film, wherein the pressing density is 799kg / m3>; step 4, fermenting and granulating at the temperature of 30 to 38 DEG C, wherein the special additive comprises the following components in parts by weight: 15 to 23 parts of humic acid, 30 to 40 parts of molasses, 8 to 12 parts of methylfumarate, 10 to 18 parts of calcium peroxide, 0.5 to 2 parts of methoxy-5-nitrophenol sodium salt, and 4 to 11 parts of polyaspartic acid. The sheep manure wrapping technology has the advantages thatthe pollution by impurity bacteria is effectively avoided, the damaged cambia cells of plant are recovered, the conversion rate of sheep manure is improved, and the nutrients are more thoroughly released.

The invention discloses a liquid synergistic fertilizer. The liquid synergistic fertilizer is prepared from the following raw materials in parts by mass: 1-20 parts of dinitrophenol, 2-20 parts of alpha-naphthylacetic acid, 3-15 parts of indoleacetic acid, 5-30 parts of indolebutyric acid, 10-30 parts of o-nitrophenol, 5-20 parts of nitrophenol, 15-45 parts of nitro-o-methoxyphenol, 20-30 parts ofo-methoxyphenol, 10-45 parts of polyoxyethylene ether and 15-35 parts of a mixed enzyme. According to the synergistic fertilizer disclosed by the invention, with the addition of the mixed enzyme, theutilization rate of the chemical fertilizer is increased, the using amount of the chemical fertilizer is reduced, the yield increasing effect is obvious, meanwhile, the pollution to the environment is reduced, and thus the purposes of increasing the yield, enhancing the efficiency, protecting the environment and reducing the cost are achieved.

The invention discloses a special carbonized straw-containing fertilizer for cabbages. The special carbonized straw-containing fertilizer for the cabbages comprises the following raw materials: carbonized straws, egg shells, gulfweeds, erythromycin dregs, soybean meal, a shell powder, urea, diammonium phosphate, potassium oxalate, potassium chloride, potassium nitrate, zinc methionate, calcium gluconate, sodium octaborate tetrahydrate, nano-sized sodium silicate, cerous oxalate, a mixed bacterial flora, carboxymethyl chitosan, polyvinyl alcohol, gelatin and a regulator, wherein the regulator is a mixture of nano-sized kaolin, sodium o-nitrophenolate, sodium 5-nitro-o-methoxyphenol, gibberellic acid, osmanthus essential oil, cinnamic acid, oxadiazon and ethoxyquinoline. The special carbonized straw-containing fertilizer for the cabbages, provided by the invention, is reasonable in formula and balanced in nutrition, and can promote the growth of the cabbages, increase the yield of the cabbages and improve the quality of the cabbages.

The invention relates to a crop growth promoting and anti-disease agent with a plurality of functions, and a manufacture and use method thereof. The agent has the following raw material formulas: 2, 4-dinitrophenol (Na) a-naphthylacetic acid (Na), indoleacetic acid (Na), o-nitrophenol (Na), p-nitrophenol (Na), 5-nitroguiacolate (Na), guaiacol (Na), N, N-diethylaminoethanol alkyl caproate, brilliant blue and a filler (which comprises methanol, carbamide, ammonium hydrogen carbonate, ammonium sulphate, ammonium chloride, lemery, potassium chloride, monopotassium phosphate, calcium-magnesia phosphate fertilizer, ordinary superphosphate, organic fertilizer and various composts, and green copperas, zinc sulfate, manganous sulfate, borax, boric acid, bluestone and water). The crop growth promoting and anti-disease agent with a plurality of functions is made by compounding and has the use method that the crop growth promoting and anti-disease agent is evenly sprayed on crops and farms after being diluted with the water which is 1000 to 5000 times the quantity of the crop growth promoting and anti-disease agent, and the dosage of the growth promoting and anti-disease agent per mu is 1 to 1000g.

The invention discloses a method for synthesizing 5-bromo-2-methoxyphenol, which comprises the steps of protecting phenolic hydroxyl of o-methoxyphenol by using a carbonate reagent, carrying out high-selectivity bromination by using N-bromo succinimide (NBS), and finally hydrolyzing and acidifying to obtain the 5-bromo-2-methoxyphenol. According to the method, o-methoxyphenol is used as a raw material, the carbonic ester reagent is used for acylation protection of phenolic hydroxyl for the first time, the reaction condition is mild, the raw material conversion is thorough, the post-treatment is very convenient, the brominated intermediate can be obtained with high yield only by suction filtration and alcohol washing, and no other by-products are generated. Finally, a target product can beobtained through conventional hydrolysis reaction. The whole reaction process is simple in purification, the solvent in each step can be recycled for multiple times, the comprehensive yield reaches 93%, and the method has a very strong application prospect and is remarkably superior to the prior art.

The invention discloses organic liquid fertilizer. The organic liquid fertilizer is prepared from the following raw materials in parts by mass: 20-40 parts of bone serous fluid, 10-15 parts of bean pulp, 2-8 parts of calcium oxide, 3-6 parts of bacillus subtilis, 2-5 parts of penicillium, 2-6 parts of chloronema, 10-30 parts of amino acid, 5-20 parts of indolebutyric acid, 10-30 parts of o-nitrophenol, 5-10 parts of nitrophenol, 15-25 parts of methoxy-5-nitrophenol, 20-30 parts of o-methoxyphenol, 5-10 parts of polyoxyethylene ether and 30-60 parts of water. The organic liquid fertilizer is added with indolebutyric acid and amino acid, so that a fertilizer usage rate is increased, and therefore, the organic liquid fertilizer has the advantages of being resistant to salt and alkaline, resistant to bacteria, efficient, and the like, reduces pollution on environment, and achieves the purposes of increasing the yield, improving efficiency, being environmentally friendly, and reducing the cost.

The invention discloses a method for preparing o-methoxyphenol from lignin. The method includes: lignin pre-activation: pre-soaking and activating lignin with ethanol and water in sequence; placing the pre-activated lignin in a high-pressure reactor, using ethanol and water as a medium, and then adding a solid acid as a catalyst, React at 200-240°C for 0.5-1 hour to obtain a reaction liquid, filter it, extract the filtrate, and concentrate the extract to obtain o-methoxyphenol. The present invention uses lignin by-products derived from agricultural and forestry wastes as raw materials to obtain o-methoxyphenol by specific process extraction, and the obtained o-methoxyphenol is pure o-methoxyphenol without any other impurities, and its application A good foundation is laid, and the preparation process is simple, the cost is low, and the method has great application prospects.

The invention provides an artificial supplementary pollination composition. The composition comprises pollen, a component I and a component II, the pollen accounts for 0.05%-0.1% of a pollination spray composition in percentage by mass, substances in the component I comprise, by mass percent in the pollination spray composition, 0.05%-0.10% of phethalanilic acid, 0.01%-0.05% of calcium nitrate, 0.0005%-0.0007% of 2-methoxy-5-nitrophenol sodium salt, 0.005%-0.01% of water-soluble gum acacia powder, 0.5%-1.0% of cane sugar, 0.0020%-0.0021% of sodium para-nitrophenolate, 0.01%-0.05% of boric acid, 0.01%-0.02% of sodium carboxymethylcellulose, 0.0012%-0.0014% of sodium 2-nitrophenolate, and 10%-20% of water. The component II is a water soluble colorant solution. The composition prepared by mixing the pollen, the component I and the component II has the advantages of accessible raw materials and lower cost, can implement commercialization, and can effectively enhance the pollen activity, promote the pollination and fertilization actions and enhance the fruit yield.

The compound 6-(2-methoxy phenoxy)-1, 4-dihydrogen-4-oxo-3-ethyl quinoline carboxylate is prepared with o-methoxyphenol and p-chloronitrobenzene as materials and through four-step reaction. The coccidian antagonist experiment on chicken shows its coccidian antagonizing effect, and compared with available coccidian antagonist medicine, the compound of the present invention has the advantages of short synthesis path, high yield, low cost, etc.

The invention relates to a cobalt catalyst used for catalyzing o-methoxy-phenol to prepare cyclohexanol and a preparation method of the cobalt catalyst. The cobalt catalyst comprises a carrier and cobalt and is prepared by a coprecipitation method. The prepared cobalt catalyst is quite high in cyclohexanol selectivity. The invention mainly relates to influence of active components loaded onto composite metal oxide carriers of different proportions on the catalytic reaction of o-methoxy-phenol. An application method of the cobalt catalyst includes: using the o-methoxy-phenol as the raw material, using a high-pressure constant flow pump to convey the raw material into a fixed bed reactor to perform reaction for 2-5 hours under 100-260 DEG C, and performing gas chromatography on obtained condensate. Results show that the cobalt catalyst is cheap in raw material, simple in preparation method, uniform in active component distribution, high in reaction activity and high in cyclohexanol yield.

The invention belongs to the field of organic synthesis, and particularly relates to a preparation method of urapidil intermediate 1-(2-methoxyphenyl) piperazine and salt thereof. According to the invention, o-methoxyphenol is used as a starting material to prepare the urapidil intermediate 1-(2-methoxyphenyl) piperazine by using a brand-new synthesis route, and methylsulfonyl chloride is adopted to activate hydroxyl on o-methoxyphenol, so that the condensation reaction condition of o-methoxyphenol and imino on piperazine is mild; and the intermediate product does not need to be separated in the intermediate process of the sulfonylation reaction and the condensation reaction, and the operation is simple and convenient. The condensation reaction adopts a mode of adding o-methoxyphenyl methanesulfonate into piperazine, so that two imino groups on piperazine are prevented from being subjected to condensation reaction at the same time, the selectivity of a target product is ensured, excessive impurities are prevented from being introduced into a system, and the purity of the product is improved. In terms of o-methoxyphenol, the total yield of the urapidil intermediate 1-(2-methoxyphenyl) piperazine prepared by the preparation method disclosed by the invention can reach 88% or above. Meanwhile, the preparation method is obvious in cost advantage and suitable for industrial production.

The synthesis process of amide derivative includes the reaction between N-methylol fatty amide with the structure of RCONHCH2OH and benzene substitute in the presence of catalyst and inside ethanol or aceitc acid and the separation purify reaction product. The process features the catalyst being H-type strong acid cationic exchange resin, which is the copolymer of sulfonated coal and sulfonated styrene or sulfonated phenolic resin; the benzene substitute being resorcin, catechol, o-methoxyphenol, m-methoxyphenol, veratrole, m-dimethoxyl benzene, o-ethoxyphenol, m-ethoxyphenol, o-diethoxyphenol or m-diethoxyphenol; and introduction of nitrogen during synthesis. The present invention has advantages of no corrosion of strong acid and the reuse of unreacted material after filtering.

The present invention relates to a growth promoting fertilizer and a preparation process thereof, wherein 0.01-1.5% of 2,4-dinitrophenol, 0.01-1.5% of a- naphthalene acetic acid, 0.01-1.5% of indole acetic acid, 0.01-1.5% of o-nitrophenol, 0.01-1.5% of p-nitrophenol, 0.01-2% of 5-nitro guaiacol, 0.01-2% of guaiacol, 2-4% of methanol, 0.01-2% of N,N-diethylamino ethanol hexanoate, 0.01-3% of citric acid, 0.01-0.5% of brilliant blue, and 85-97% of a compound fertilizer are completely mixed, and processing granulation is performed according to a compound fertilizer manufacturing method. According to the present invention, the growth promoting fertilizer has characteristics of fertilizer utilization rate improving, fertilizer consumption reducing, significant yield increase, rapid effect providing, environmental pollution reducing, crop quality improving, yield increase, effect increase, and cost reduction.