55results about How to "Evenly groomed" patented technology

The invention relates to a making method and an application of a mycotoxin photoelectrochemical sensor for in situ generation of CdS. The method uses cerium dioxide doped reduced graphene oxide as an antibody capture substrate, and the cerium dioxide doped reduced graphene oxide has good conductivity and large specific surface area, and can effectively reduce background signals. Na2S is directly dropped to the surface of an electrode with Cd<2+> functionalized porous TiO2 nanoparticles as a semiantigen marker carrier in order to realize in situ generation of narrow band gap CdS with a high photoelectric conversion rate, and a photoelectric current signal can be generated through irridating the CdS by an LED lamp of visible light wavelength. The carrier TiO2 can be well matched with the energy band of the CdS in order to further improve the photoelectric conversion signal of the CdS, so the competitive photoelectrochemical sensor for super sensitive detection of zearalenone, alpha-zeranol, aflatoxin B1, aflatoxin B2, ochratoxin A, ochratoxin B and other mycotoxins is made.

The invention relates to a preparation method of a photoelectrochemical sensor for detecting dexamethasone based on in-situ generation of cadmium sulfide. The method specifically comprises the following steps: as carboxylated carbon nitride and bismuth sulfide are taken as substrate materials, and labeling a dexamethasone antibody by using titanium dioxide subjected to cadmium ion functionalization. Sodium sulfide is directly dropwise added to the electrode surface, a narrow band-gap cadmium sulfide semiconductor nanometer material with the high photoelectric conversion efficiency is generated in situ, and a photocurrent signal is generated under light source irradiation with visible wavelength. A porous titanium dioxide carrier and a cadmium sulfide energy band are well matched, so that the photoelectric conversion efficiency of the cadmium sulfide is improved, the high-sensitivity detection of dexamethasone is realized, and the detection limit is 2pg/mL.

The invention discloses a preparation method of a modified high-nickel ternary positive electrode material, which comprises the steps of uniformly mixing a nickel-cobalt-manganese hydroxide precursor with a lithium source and a magnesium source, and carrying out two-stage sintering to obtain a magnesium-doped ternary high-nickel positive electrode material; and dispersing the magnesium-doped ternary high-nickel positive electrode material in an organic solvent, then adding a vanadium source and a lithium source, uniformly stirring, heating, evaporating to dryness, drying, and sintering at high temperature to obtain the lithium vanadate-coated magnesium-doped high-nickel ternary positive electrode material. According to the modified high-nickel ternary positive electrode material disclosed by the invention, the cycle performance and the rate capability of the material can be synergistically improved due to the high-nickel ternary positive electrode material is subjected to double modification treatment of magnesium ion doping and fast ion conductor coating.

The invention relates to a preparation method of nano-magnetic beads modified by gold nanoparticles. The preparation method comprises the following steps: (1) dispersing ferroferric oxide nano-magnetic beads in a sugar solution, and carrying out a hydrothermal reaction at 160-220 DEG C so as to obtain nano-magnetic beads modified through glycosylation, wherein a monosaccharide solution or an oligosaccharide solution serves as the sugar solution; and (2) dispersing the nano-magnetic beads modified through glycosylation in a trisodium citrate solution, and then adding a chloroauric acid solutionfor a reduction reaction, so as to obtain the nano-magnetic beads modified by the gold nanoparticles. The preparation process is simple; the surfaces of the obtained nano-magnetic beads are uniformlymodified; and meanwhile, the stability and the application performance of such composite magnetic beads are improved.

The invention relates to a silicon dioxide loaded chitosan modified waterborne polyurethane acrylate composite emulsion, a preparation method therefor and an application of the composite emulsion. Themethod comprises the steps: (1) dispersing macroporous sillca nanoparticles in deionized water through ultrasonic dispersion, adding a chitosan solution, and carrying out uniform mixing; (2) carryingout filtering so as to obtain a filter cake, removing impurities from the filter cake, and then, carrying out drying, so as to obtain macroporous sillca loaded chitosan nanoparticles; and (3) dispersing the particles in deionized water through ultrasonic dispersion, adding the dispersion into a waterborne polyurethane acrylate emulsion, and carrying out uniform mixing, thereby obtaining the composite emulsion. According to the composite emulsion, chitosan can be released continuously to achieve a long-acting antibacterial effect, and the permeability to water vapor and antibacterial propertyof a film formed by waterborne polyurethane acrylate are improved; and when the composite emulsion serves as a leather finishing agent, the tensile strength, tear strength and permeability to water vapor of a leather sample can be increased by 6.25%, 6.67% and 197.42% separately, and an inhibition zone can reach 30mm.

The invention belongs to the technical field of molecular biology and in particular relates to an SERS probe and an SERS substrate labeled by multiple antibodies as well as a preparation method and application of the SERS probe and the SERS substrate. Dopamine is embedded and combined with multiple antibodies under auto-polymerization conditions so as to obtain the SERS substrate and the SERS labeled probe modified by the polydopamine and the antibodies. By virtue of immune binding force, high-sensitivity detection and diagnosis of exosome extracted from pancreatic cancer cells and serum samples of clinical pancreatic cancer patients can be realized by utilizing Raman spectroscopy. Statistical data analysis discovers that an SERS platform based on an MIF antibody is capable of realizing phased tumor judgment of the pancreatic cancer. The SERS probe disclosed by the invention is simple and convenient in labeling method, is used for detection of exosome of the pancreatic cancer, is rapid, sensitive, high in specificity and small in amount of needed samples, does not need a high-speed centrifugal separation process and can be applicable to clinical diagnosis and phased tumor metastasis judgment.

The invention provides a synthesis method of PEDOT loaded grapheme. The synthesis method of PEDOT loaded graphene is characterized in that the synthesis method of the PEDOT loaded grapheme comprises the following steps that EDOT monomer is dissolved in isopropanol, graphite oxide is added, ultrasonically stirring and dispersing are carried out to form sol; ferric trichloride is dissolved in a deionized water solution, the mixture is slowly added into first sol, and continuously stirring is carried out during the adding process to obtain mixed mother liquor; a potassium iodide solution is added, continuously stirring and reacting at room temperature for 8-24 hours are carried out to obtain precipitate, the precipitate is washed and dried to obtain PEDOT loaded graphene powder. All the raw materials are common cheap chemicals, are synthesized by adopting a green process, PEDOT obtained by in-situ polymerization in the graphite oxide sol is uniformly modified on graphene oxide, then KI isused for reducing graphite oxide, and a product I2 is absorbed by PEDOT, so that uniform modification of the PEDOT on the surface of reduced highly conductive graphene is achieved, and the effect ofsynergistically increasing conductivity is achieved.

Provided is a human interferon, wherein at least one amino acid residue is replaced with Lys-azido. Further provided is a pegylated human interferon, which improves in vivo stability of the human interferon. Additionally, provided is a method for preparing the interferon and a pegylated product thereof, which comprises using a plasmid which can express tRNAPyl/PylRS.

The invention discloses a Ti3C2-MXene modified alpha-iron oxide photoelectrode and a preparation method thereof, and relates to the technical field of nano materials. The method comprises the following steps: dipping FTO conductive glass into a reaction kettle containing a mixed aqueous solution of ferric salt and Ti3C2-MXene, co-depositing iron oxide and Ti3C2-MXene on the surface of FTO conductive glass by using a hydrothermal method, and carrying out annealing treatment to obtain the Ti3C2-MXene modified alpha-iron oxide photoelectrode. According to the Ti3C2-MXene modification method, theproblems that traditional alpha-iron oxide is poor in conductivity, short in surface carrier life and the like are solved, the photoelectric conversion efficiency of the alpha-iron oxide is improved,and then the photoelectrocatalysis capacity of the alpha-iron oxide is improved.

The invention discloses a porous carbon modified glassy carbon electrode, which is prepared by the steps of pyrolyzing sodium alginate under the protection of nitrogen, cooling a carbon material obtained by pyrolysis to room temperature, adding the carbon material into hydrochloric acid with the concentration of 1-5mol/L, soaking and stirring for 20-60 minutes, washing with distilled water to be neutral, and drying to obtain porous carbon; dispersing porous carbon into N,N-dimethylformamide, and carrying out uniform ultrasonic dispersion to obtain a porous carbon dispersion liquid; and polishing a glassy carbon electrode with Al2O3 until the mirror surface is smooth, then sequentially carrying out ultrasonic cleaning with ethanol and secondary distilled water, washing with the secondary distilled water, blow-drying, dropwise adding the porous carbon dispersion liquid, and drying to obtain the porous carbon modified glassy carbon electrode. A three-electrode system composed of the porous carbon modified glassy carbon electrode can distinguish oxidation peaks of catechol, hydroquinone and resorcinol, significantly enhances electrochemical signals of three target objects, improves thedetection sensitivity, and can be used for determination of actual environmental water samples.

The invention discloses a Pt or Au modified porous PdFe intermetallic compound, and a preparation method and an application thereof, and belongs to the technical field of electrochemistry. An intermetallic compound is a nanoparticle; an inner core of the nanoparticle is an ordered PdFe intermetallic compound; the surface of the nanoparticle is of a porous structure with uniformly distributed Pd; and the surface of the porous structure is modified with Pt or Au. The preparation method comprises the steps of using palladium acetate and ferric salt as metal sources, and loading the metal sourceson a carbon carrier; then thermally decomposing acetate in a protective atmosphere to obtain a supported PdFe intermetallic compound; and after Fe on the surface is etched away, adopting a surface modification technology to prepare the Pt or Au modified PdFe intermetallic compound with the porous surface and the ordered inner core. The Pt or Au modified porous PdFe intermetallic compound preparedby the method shows relatively high activity and stability as a negative oxygen reduction reaction catalyst and a positive hydrogen oxidation reaction catalyst of a fuel cell.

The invention relates to the technical field of preparation of artificial bone repair materials in the field of inorganic nonmetallic materials and biomedical materials, in particular to a preparationmethod of a high-biological activity support material. The preparation method of the high-biological activity support material, provided by the invention, comprises the following steps: a titanium-based titanate nano-wire matrix is made of a titanium sheet, homemade solid graphene oxide is configured into turbid liquid, a graphene nano-sheet suspension is obtained by adding sodium hydroxide, chloroacetic acid and other substances through ultrasonic dispersion, and the titanium-based titanate nano-wire matrix is subjected to electrophoretic deposition with deposition liquid to obtain the high-biological activity scaffold material. Graphene oxide is deposited and modified on the surface of the matrix, so that the biocompatibility and the biological activity of the support material are improved; a coating solution used is a silk fibroin stock solution and casein, is high in degradation property and does not produce any toxic substance; and through the functionalization of the chloroacetic acid, 1,3-propylenediamine and the like for hydroxyl, amino and carboxyl of the graphene oxide, the bone induction ability of a unfunctionalized support material is further improved, and therefore,the application prospect is wide.

The invention relates to a measurement device for a material wearing capacity and a wearing temperature field. According to the technical scheme, a motor (7) of a friction mechanism (1) is connected with an abrasive disk (11) through a shaft, a press beam (10) is hinged to a rotatable press beam base (9), and a sample (13) to be measured is installed in a sample fixing sleeve (12) of the press beam (10); a lubricant container (18) of a flow control mechanism (3) is connected with a supercharger (19), a sliding valve (20) and a dropper (21) in sequence through hoses; the lower end of a lead screw (27) of a wear measuring mechanism (4) penetrates through a lead screw base (26) to be spherically hinged to a sliding block (25) which is connected with a pressure head (23) through a spring (24), and a wear scale (32) and a load scale (30) are arranged on the side wall of a loading stand column (22); a thermocouple (34) is installed on a thermocouple fixing rod (33) of a temperature measurement mechanism (5), a motor controller (2) is electrically connected with the motor (7), and the thermocouple (34) is electrically connected with a paperless temperature recorder (6). The measurement device for the material wearing capacity and the wearing temperature field has the advantages of being simple in structure, low in cost, convenient to maintain and high in universality.