3results about How to "Regulatory function" patented technology

The invention discloses an atropine derivative and a preparation method and application thereof, and belongs to the technical field of medical preparations, the atropine derivative and a salt or a pharmaceutical composition thereof can be used as a ciliary muscle paralysis agent and / or a mydriasis agent; the choroid and sclera functions can be regulated and controlled by improving choroid microcirculation and sclera hypoxia environment, inhibiting an HIF-1alpha signal channel and directly targeting sclera fibroblasts to inhibit extracellular matrix generation and remodeling; the medicine is used for relieving muscae volitantes symptoms; amblyopia, lazy eye diseases or myopia can be relieved; for treating or preventing myopia; the traditional Chinese medicine composition has good maintenance time and treatment effect, can obviously reduce the use frequency and use amount, improves the use experience, and reduces the medicine use cost.

This invention provides a rumen methane inhibitor and its application, belonging to the field of ruminant farming. The active ingredients of the rumen methane inhibitor of this invention include: *Lactobacillus reuteri* inoculum, *Lactobacillus gasseri* inoculum, *Lactobacillus casei* inoculum, amylase, phytase, xylanase, cellulase, and β-glucanase. The rumen methane inhibitor can effectively regulate the intestinal microbiota of dairy cows, promote the decomposition of fibrous material in the rumen, optimize the rumen fermentation environment, thereby controlling rumen function, reducing methane production, and improving the productivity of ruminants. The rumen methane inhibitor is safe and environmentally friendly, which is conducive to its application in ruminant farming, agriculture, and other fields, and has good practicality.

The invention belongs to the field of biological medicine, and relates to a marker FOXP4 for liver cancer diagnosis, typing and prognosis and application thereof, in particular to an FOXP4 inhibitor and application thereof. A public database and animal experiments fully verify that the FOXP4 plays an important role in the liver cancer occurrence process, and prove that the expression of the FOXP4 can be used as a biomarker for liver cancer diagnosis. The liver cells are subjected to gene editing by utilizing multiple recombinant plasmids, so that the proliferation and differentiation functions of the liver cells can be regulated and controlled in a knockout and refilling manner, and a new thought is provided for developing a novel medicine for treating or relieving the liver cancer.