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Medicinal composition for tonifying kidney and eliminating obstruction, and its preparing method

A composition and drug technology, which is applied in the direction of drug combination, pharmaceutical formula, medical raw materials derived from ferns/filamentous plants, etc., can solve the problems of long treatment period for bone and joint diseases, affecting the safety of clinical medication of Yishen Juanbi Pills, etc. , to achieve the effect of reducing toxic and side effects and ensuring curative effect

Inactive Publication Date: 2007-09-05
JIANGSU QINGJIANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In particular, the course of treatment for rheumatism, rheumatoid arthritis and various bone and joint diseases is relatively long. The original prescription contains Xugufeng medicinal materials containing aristolochic acid, which seriously affects the clinical medication safety of Yishen Juanbi Pills.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Preparation of pharmaceutical composition tablet of the present invention (improved preparation of Yishen Juanbi pill)

[0039] 1) Weigh 66 grams of hive, 66 grams of drynariae, 66 grams of angelica, 66 grams of soft-shelled turtle, 66 grams of black snake, 66 grams of epimedium, 66 grams of rehmannia glutinosa, 66 grams of Xu Changqing, 66 grams of silkworm, 66 grams of earthworm, 66 grams of chrysanthemum, 66 grams of corydalis, 10 grams of centipede, 10 grams of scorpion, 83 grams of geranium, 83 grams of knotweed, 83 grams of milletus, 113 grams of rehmannia, and 83 grams of humulus.

[0040] 2) Get the hive, Guangdilong, Yanhusuo, black snake, and silkworm according to the "Jiangsu Provincial Traditional Chinese Medicine Processing Standard" 2002 edition (edited by Jiangsu Provincial Drug Administration, chief editor Chen Zhenfei, Jiangsu Science and Technology Press, published in 2002) To concoct:

[0041] Honeycomb (stir-fried): The raw medicinal materials are c...

Embodiment 2

[0055] The preparation of pharmaceutical composition capsule of the present invention

[0056] 1) Weigh 40 grams of hive, 40 grams of drynaria, 40 grams of angelica, 40 grams of soft-shelled turtle, 40 grams of black snake, 40 grams of epimedium, 60 grams of rehmannia glutinosa, 40 grams of Xu Changqing, 40 grams of silkworm, 40 grams of Dilong, 40 grams of Luniancao, 40 grams of Corydalis, 1 gram of Centipede, 1 gram of Scorpion, 60 grams of Geranium, 60 grams of Polygonum cuspidatum, 60 grams of Caulis Spatholobus, 80 grams of Dihuang, and 60 grams of Humulus.

[0057] 2) Stir-fry the honeycomb of the prescribed amount, stir-fry the stiff silkworm bran, make Guangdilong wine, Wushaoshe wine, and Corydalis vinegar (same as Example 1). Stir-fried honeycombs, bran-fried stiff silkworms, wine-made Guangdilong, wine-made black snake, vinegar-made Corydalis, set aside;

[0058] 3) Decoct the prescription amount of Geranium, Polygonum cuspidatum, Millipede spatholobus, Rehmannia g...

Embodiment 3

[0061] The preparation of pharmaceutical composition pill of the present invention

[0062] 1) Weigh 80 grams of hive, 80 grams of drynariae, 80 grams of angelica, 80 grams of cuttlefish, 80 grams of black snake, 80 grams of epimedium, 100 grams of rehmannia glutinosa, 80 grams of Xu Changqing, 80 grams of silkworm, 80 grams of earthworm, 80 grams of chrysanthemum, 80 grams of corydalis, 20 grams of centipede, 20 grams of scorpion, 100 grams of geranium, 100 grams of knotweed, 100 grams of milletus, 120 grams of rehmannia, and 100 grams of humulus.

[0063] 2) Stir-fry the honeycomb of the prescribed amount, stir-fry the stiff silkworm bran, make Guangdilong wine, Wushaoshe wine, and Corydalis vinegar (same as Example 1). Stir-fried honeycombs, bran-fried stiff silkworms, wine-made Guangdilong, wine-made black snake, vinegar-made Corydalis, set aside;

[0064] 3) Decoct the prescription amount of Geranium, Polygonum cuspidatum, Millipede spatholobus, Rehmannia glutinosa, and ...

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PUM

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Abstract

The present invention relates to an improved preparation of Yishen Juanbi Wan containing no aristolochine and its preparation method. The pharmacodynamic tests show that after the Chinese medicinal material hairy birthwort is removed from original prescription of Chinese medicine Yishen Juanbi Wan, the medicine effects of warming and recuperating the kidney-yang, tonifying kidney and strengthening bone, expelling pathogenic factors and removing obstruction is the channels, etc. of the Yishen Juanbi medicine composition prepared by said invention are not changed, so that said invention can reduce toxic side effect of its original prescription.

Description

field of invention [0001] The invention relates to a pharmaceutical composition for treating rheumatism, rheumatoid arthritis and various bone and joint diseases and a preparation method thereof, in particular to a medicinal composition for nourishing kidney and juanbi from which toxic substances have been removed, and a preparation method thereof. technical background [0002] Yishen Juanbi Pills ("Ministry of Health Drug Standard 92 Year Edition" variety) is a traditional Chinese medicine in my country, which is used to treat rheumatism, rheumatoid arthritis and various bone and joint diseases. In terms of the treatment of rheumatoid arthritis, there are currently no treatment options and medicines recognized by the public at home and abroad. Commonly used medicines are western medicines, such as non-steroidal anti-inflammatory drugs, including indomethacin, ibuprofen, and naproxen Diclofenac sodium, etc. Although they have analgesic effect, they only improve the condition...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/804A61K36/11A61K36/232A61K35/58A61K36/296A61K36/27A61K35/64A61K36/185A61K9/20A61K9/48A61P29/00A61P19/02A61K35/583
Inventor 韩才峰成爱东
Owner JIANGSU QINGJIANG PHARMA
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