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Filter apparatus and blood detection container

A filter and blood technology, applied in the field of plasma or serum separation membrane, can solve the problems of unsatisfactory filtration speed, pollution, high cost, etc.

Inactive Publication Date: 2009-05-27
SEKISUI MEDICAL CO LTD +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, the method disclosed in Japanese Examined Patent Publication No. 2-23831 (1990) has economical problems because the use of hollow fibers requires high cost to produce disposable products
[0007] The method disclosed in Japanese Examined Patent Publication No. 6-64054 is capable of separating plasma or serum, but the filtration rate is still unsatisfactory
Application of pressure to improve filtration rate can sometimes lead to rupture of blood cells, lysis of blood cells (hemolysis), and contamination of separated plasma or serum by leaking red blood cells

Method used

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  • Filter apparatus and blood detection container
  • Filter apparatus and blood detection container
  • Filter apparatus and blood detection container

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0121] Prepare a separation membrane made of polycarbonate with a thickness of 10 μm (manufactured by Millipore, product number: GTTP04700, the separation membrane has a plurality of through holes with a circular cross-section, and the size of the pores is 0.2 μm). The separation membrane was cut into small pieces with a diameter of 13 mm, and placed in a commercially available filter cartridge (manufactured by Millipore Corporation, trade name: Sphinex filter holder S x 0130000).

example 2

[0123] An evaluation sample was prepared in the same manner as in Example 1 except that the diameter of the through hole was changed to 0.6 µm.

example 3

[0125] An evaluation sample was prepared in the same manner as in Example 1 except that the diameter of the through hole was changed to 2.0 µm.

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Abstract

A Plasma or serum separation membrane that enables omitting centrifugal separation, is free from hemolysis attributed to destruction of red blood cells and realizes easy and rapid separation of plasma or serum from blood; and a filter apparatus including the plasma or serum separation membrane. In particular, a plasma or serum separation membrane being a membrane for separation of plasma or serum from blood and having a void ratio of 30% or below; and a filter apparatus comprising a filter member capable of attaining movement of plasma swifter than movement of blood cells and a plasma or serum separation membrane connected in series with a rear side of the filter member.

Description

technical field [0001] The present invention relates to a plasma or serum separation membrane for separating plasma or serum components in blood containing blood cells, more particularly, to a plasma or serum separation membrane capable of successfully separating plasma or serum components without damaging red blood cells and Filter. The invention also relates to blood testing containers. Background technique [0002] Generally, in order to remove blood cells from blood to obtain plasma or serum required for experiments, various separation membranes have been proposed. [0003] For example, Japanese Examined Patent Publication No. 2-23831 (1990) discloses a method for collecting plasma from blood using a hollow fiber having micropores with a diameter of 0.05 to 1 μm, the porosity of the outer surface of which is not more than 40%, and the porosity of the inner surface is not less than 60%. [0004] Japanese Examined Patent Publication No.6-64054 (1994) proposes a method o...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N33/48B01D69/06B01D63/08
Inventor 户川胜也冈本隆介五十川浩信
Owner SEKISUI MEDICAL CO LTD
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