Plasma or serum separation membrane and filter apparatus including the plasma or serum separation membrane

Abstract

A plasma or serum separation membrane capable of omitting centrifugation, without hemolysis caused by red blood cell destruction, capable of conveniently and quickly separating plasma or serum from blood; and a filter comprising a plasma or serum separation membrane. In particular, a plasma or serum separation membrane is a membrane that separates plasma or serum from blood and has a void ratio of 30% or less; and a filter that includes a filter element capable of moving plasma faster than blood cells And the plasma or serum separation membrane sequentially connected with the rear side of the filter element.

Description

technical field [0001] The present invention relates to a plasma or serum separation membrane for separating plasma or serum components in blood containing blood cells, more particularly, to a plasma or serum separation membrane capable of successfully separating plasma or serum components without damaging red blood cells and Filter. Background technique [0002] Generally, in order to remove blood cells from blood to obtain plasma or serum required for experiments, various separation membranes have been proposed. [0003] For example, Japanese Examined Patent Publication No. 2-23831 (1990) discloses a method for collecting plasma from blood using a hollow fiber having micropores with a diameter of 0.05 to 1 μm, the porosity of the outer surface of which is not more than 40%, and the porosity of the inner surface is not less than 60%. [0004] Japanese Examined Patent Publication No.6-64054 (1994) proposes a method of passing through an average diameter of 0.2 to 5.0 μm an...

AI Technical Summary

Problems solved by technology

[0006] However, the method disclosed in Japanese Examined Patent Publication No. 2-23831 (1990) has economical problems because the use of hollow fibers requires high cost to produce disposable products

[0007] The method disclosed in Japanese Examined Patent Publication No. 6-64054 is capable of separating plasma or serum, but the filtration rate is still unsatisfactory

Application of pressure to improve filtration rate can sometimes lead to rupture of blood cells, lysis of blood cells (hemolysis), and contamination of separated plasma or serum by leaking red blood cells

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