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86 results about "Blood erythrocytes" patented technology
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Erythrocytes in Peripheral Blood. Erythrocytes, or red blood cells, transport oxygen from the lungs to the rest of the body and carbon dioxide in the opposite direction.Red blood cells can vary in size, shape and color and their characteristics are helpful in the diagnosis of for example anemia.
Composition and method for the repair and regeneration of cartilage and other tissues
InactiveUS20060029578A1Add supportImprove coagulation/solidificationBiocideOrganic active ingredientsAbnormal tissue growthRepair tissue
The present invention relates to a new method for repairing human or animal tissues such as cartilage, meniscus, ligament, tendon, bone, skin, cornea, periodontal tissues, abscesses, resected tumors, and ulcers. The method comprises the step of introducing into the tissue a temperature-dependent polymer gel composition such that the composition adhere to the tissue and promote support for cell proliferation for repairing the tissue. Other than a polymer, the composition preferably comprises a blood component such as whole blood, processed blood, venous blood, arterial blood, blood from bone, blood from bone-marrow, bone marrow, umbilical cord blood, placenta blood, erythrocytes, leukocytes, monocytes, platelets, fibrinogen, thrombin and platelet rich plasma. The present invention also relates to a new composition to be used with the method of the present invention.
Owner:SMITH & NEPHEW ORTHOPAEDICS
Plasma or serum separation membrane and filter apparatus including the plasma or serum separation membrane
ActiveCN1714292ASafe, reliable and fast separationDoes not cause ruptureBiological testingVoid ratioHemolysis
A plasma or serum separation membrane capable of omitting centrifugation, without hemolysis caused by red blood cell destruction, capable of conveniently and quickly separating plasma or serum from blood; and a filter comprising a plasma or serum separation membrane. In particular, a plasma or serum separation membrane is a membrane that separates plasma or serum from blood and has a void ratio of 30% or less; and a filter that includes a filter element capable of moving plasma faster than blood cells And the plasma or serum separation membrane sequentially connected with the rear side of the filter element.
Owner:SEKISUI MEDICAL CO LTD +2
Method for measuring materials inside human single blood erythrocyte by mocro-fluidic chip chemiluminescence
InactiveCN101672788AFast analysisHigh sensitivityChemiluminescene/bioluminescenceCysteine thiolateData acquisition
The invention provides a method for measuring materials inside human single blood erythrocyte by mocro-fluidic chip chemiluminescence, which can analyze the contents of cysteine, glutathione and hemoglobin in a single blood erythrocyte. An electrophoresis chemiluminescence detection system of a mocro-fluidic chip is adopted; five power supply output ends of a high voltage power supply are respectively connected with a buffer solution pool B, a sample pool S, a waste liquie pool SW, a chemiluminescence reagent pool R and a buffer waste liquie pool BW of the mocro-fluidic chip; the mocro-fluidicchip is arranged on an objective lens of a chemiluminescence detector; the chemiluminescence detector is an inverted microscope combined with a photomultiplier; the photomultiplier is electrically connected with a data collector; and the data collector is electrically connected with a computer. The method can carry out early diagnosis on occurrence of lesions by measuring the increased degree ofthe concentration of the glutathione and the cysteine in the single blood erythrocyte, has high analysis speed, high sensitivity and high resolution, is suitable for early diagnosis to health examination and the lesions of a human body, and can be used as an effective means of preventive medicine.
Owner:GUANGXI NORMAL UNIV
Magnetic and fluid velocity pressure mix suspending mechanical heart blood pump
InactiveCN101244296AImprove the lubrication effectNo wearPump componentsPump installationsMagnetic tension forceImpeller
The invention relates to a blood pump for assisting blood flow in the heart, in particular to an artificial heart blood pump with magnetic and fluid dynamic pressure hybrid suspension, which comprises a casing 7 sleeved on an inner shell 9; wherein the casing comprises a motor stator 8 and the inner shell 9 comprises a head support component 1, a rotor component and a rear support component 15. The blood bump is characterized in that the rotor component, the head support component 1 and the rear support component 15 are arranged in the cylindrical inner shell 9; the rotor component is arranged between the head support component 1 the rear support component 15; wherein a head blood dynamic pressure suspension cone bearing 2 is positioned at the central head support component 1; the rotor component comprises a head blood dynamic pressure suspension cone 3, an impeller 6, a rear permanent magnet bearing inner ring 10 and a rear blood dynamic pressure suspension cone 13 in series; a rear blood dynamic pressure suspension cone bearing 14 is arranged at the central rear support component 15 and a rear permanent magnet bearing external ring 12 is embedded on the outside of the bearing. The blood pump has the advantages of low shearing force of the blood, less damage to blood erythrocytes and decreased hemolysis.
Owner:BEIJING UNIV OF TECH
Preparation of water soluble pearl powder and method for producing soft capsule
InactiveCN101611862AAvoid excessive oxidationPrevent excessive agglutinationFood preparationCellular respirationHuman body
The invention relates to a health product, in particular to a soft capsule and a method for producing the same. The soft capsule is characterized in that: the soft capsule contains water soluble pearl powder, selenium-enriched yeast, natural vitamin E, beeswax, glycerol monostearate, span-80 and corn oil. The soft capsule is a powerful antioxidant which can effectively improve the rancidity of fatty acid in food and the alimentary tract, and protect cells from being damaged by harmful matters generated by oxidation of unsaturated fatty acid; the soft capsule is an extremely good free radical scavenger which can protect biological membranes from being attacked by free radicals, effectively resist ageing nutrients, improve immunity of a human body, keep the integrity of red blood cells and promote the biological synthesis of the red blood cells; the soft capsule is an indispensible promoting factor for cellular respiration, which can protect the lung tissue from air pollution; moreover, the soft capsule also can prevent the over-aggregation of blood platelets, avoid the increase of lipid peroxidation in the blood, prevent cardiovascular diseases and supplementing calcium element in the human body.
Owner:威海紫光生物科技开发有限公司
Artificial heart blood-pump capable of increasing blood pressure step by step
The invention discloses a mechanical heart blood pump which boosts blood pressure steps by steps, pertaining to the technical field of biomedical engineering, relating to a mechanical heart blood pump for boosting blood pressure. The mechanical heart blood pump comprises a driving stator and a rotor; a controller connected with a driving stator provides a driving power source; the driving stator composed of annular coils is located in an interlayer composed of a cylindrical shell 13 and a tubular cavity 10; a supporting rotor comprises a head guide vane 1 and a tail guide vane 8; the head guide vane 1 is arranged in the front end of the tubular cavity 10, the tail guide vane 8 is arranged in the rear end of the tubular cavity 10 and a rotor between the head guide vane 1 and the tail guide vane 8 is also arranged in the tubular cavity 10. The mechanical heart blood pump is characterized in that: the mechanical heart blood pump is divided into a front grade and a rear grade, wherein, the front grade is a Grade 1 blood pump and the rear grade is a Grade 2 blood pump; the Grade 1 blood pump and the Grade 2 blood pump are respectively driven by the controller. The blood firstly flows through the Grade 1 blood pump to generate a blood pressure and then flows through the Grade 2 blood pump to generate another blood pressure; the two blood pressures are overlaid to reach a blood pressure needed by the human body, thus avoiding the problem that red blood cells are injured by the rotational speed increase of an impeller when a single blood pump works to obtain a relatively high blood pressure.
Owner:BEIJING UNIV OF TECH
Opto-acoustic Doppler blood flow rate measurement method and system for determining oxygen content of red blood cells
InactiveCN105030223AMeasurement applicableLarge detection depthDiagnostic recording/measuringSensorsFrequency spectrumUltrasonic sensor
The invention discloses an opto-acoustic Doppler blood flow rate measurement method and a measurement system for determining oxygen content of red blood cells. According to the measurement system, multiple paths of laser beams coded by intensity modulation frequency and with different wavelengths focus and illuminate the same area of a blood vessel, and a lock-in amplifier is adopted for demodulating to obtain opto-acoustic Doppler frequency spectrum signals obtained by an ultrasonic transducer and positioned at different center frequencies. The measurement method and the measurement system have the characteristics that photoacoustic spectrometry of red blood cells change along with oxygen content, the flow rate and the flow direction of blood can be accurately determined, the oxygen content of blood also can be determined, so that arterial blood and venous blood can be distinguished. The measurement method and the measurement system can be used for researching blood microcirculation, and through the simultaneous detection on the flow rate of the blood and the oxygen content of the blood, the metabolism condition of the local tissue is obtained.
Owner:NANKAI UNIV
Whole blood assay
InactiveCN101680876ABiological material analysisBiological testingContinuous measurementChemical reaction
A method and apparatus to estimate the concentration of a target substance (e.g. Cholesterol or CRP) in the plasma component of awhole blood sample without the need to separate the red blood cells from the plasma prior to testing,thereby simplifying the design and construction of the test device. The invention achieves this by measuring the analyte under investigation in a time dependent (bio- / immuno-) chemical reaction and measuring separately, a marker substance (e.g haemoglobin) for the estimation of red blood cell volume, using a non-time-dependent alteration in physical property of the reaction mixture (in this instance, transmission) attributed to inherent filter effects on sample addition. These non-time- dependent changes are not part of the reaction chemistry, and are resolved from the time dependent alteration in physical property caused by the assay chemistry by continuous measurement and mathematical modelling. Algorithms that combine these two parameters are used to estimate the target substance and compensate for variations in the percentage haematocrit of the sample. The method equalises the assay response for subtle variations in patient sample (e.g. haematocrit).
Owner:QUOTIENT DIAGNOSTICS
Method for determining the existence and/or content of an analyte in a blood sample, and detecting element
ActiveCN1558235APreparing sample for investigationInvestigating moving sheetsAnalyteWhole blood units
A method for determining the presence and / or amount of an analyte in a sample of whole blood comprises the step of treating the sample with a nonlytic hypertonic salt composition to reduce the hematocrit by reducing the size of the red blood cells. In optical detection systems, the smaller red blood cells create greater scatter, which allows a more accurate correction to be applied in a dual-wavelength detection system. In electrochemical detection systems, as well as in optical detection systems, the smaller red blood cells provide less obstruction to the diffusion of analyte and reagents in the sample, to facilitate the reactions thereof.
Owner:BAYER HEALTHCARE LLC
Musca domestic pupae natural antimicrobial peptide products and preparation method and use thereof
InactiveCN101392020AMeet production needsLess likely to develop drug resistanceCosmetic preparationsPeptide/protein ingredientsFiltrationUltrafiltration
The invention relates to a house-fly pupa natural antibiotic peptide product as well as a preparation method and application thereof; house-fly pupas, the raw material of the antibiotic peptide product, are extracted overnight by acid and hot-processed to collect supernatant; and after going through siever filtration and ultrafiltration precessing, the supernatant is treated with spray dring to obtain the antibiotic peptide product. The preparation technique of the antibiotic peptide product is simple and quick, the yield of the antibiotic peptide reaches 1.2 percent and the recovery rate of the antibacterial activity is over 80 percent. The prepared house-fly antibiotic product consists of peptides which have the molecular weight less than 20kDa and are mainly micromolecular peptides with the molecular weight less than 14.4 kDa. The antibiotic peptide product has broad-spectrum antibiotic activity and no hemolytic activity to blood erythrocytes of mice and is characterized by high temperature resistance, acid and alkali resistance and good stability. The byproducts of the technique can serve as feeding insect protein powder. The prepared antibiotic peptide product can be widely applied to the fields such as the antisepsis and storage of foods, fruits and vegetables, feed additives, cosmetic and the like.
Owner:SUN YAT SEN UNIV
Giant salamander mucinous protein, preparation method and applications in cosmetics
ActiveCN103613654APromote growthReduce permeabilityCosmetic preparationsToilet preparationsRed blood cellTyrosine
The invention discloses a giant salamander mucinous protein, a preparation method and applications in cosmetics. The giant salamander mucinous protein has a molecular weight of 17000D, contains two subunits with a molecular weight of 8500D. The subunit contains 77 amino acid residues and the N end is valine-glycine-tyrosine-threonine-valine-glycine-alanine-threonine-proline-methionine-. The giant salamander mucinous protein has functions of agglutinating red blood cell activity, reducing capillary permeability, promoting cell growth and the like. Cosmetics prepared from the giant salamander mucinous protein can improve skin telangiectasis (known as couperose skin) effectively.
Owner:ZHANGJIAJIE JINCHI ANDRIAS DAVIDIANUS BIOLOGICAL SCI
Reagent and method for quantitatively detecting serum amyloid proteins A in whole blood
ActiveCN106290907ASample requirement is smallReduce dosagePreparing sample for investigationColor/spectral properties measurementsRed blood cellLatex particle
The invention discloses a reagent for quantitatively detecting serum amyloid proteins A in whole blood. The reagent comprises reagents R1 and reagents R2. The reagents R1 comprise disruption components, buffer solution, surfactants, electrolyte, preservatives, reaction promoters and stabilizers; the reagents R2 comprise latex particles, surfactants, electrolyte, preservatives, stabilizers and buffer solution; the disruption components are used for removing measurement interference red blood cells, blood cells are not separated by the disruption components, and the original whole blood can be used; anti-human SAA antibodies are coated by the latex particles, and the particle sizes of the latex particles are 50-300 nm. The reagent has the advantages that a detection sample can be the whole blood such as peripheral blood, requirements on high sensitivity and wide linear ranges can be simultaneously met, the reagent is excellent in anti-interference performance, accuracy and precision, and clinical examination requirements can be met. The invention further discloses a method for quantitatively detecting the serum amyloid proteins A in the whole blood.
Owner:PUREBIO LAB NINGBO
Method for improving antibacterial activity and biocompatibility of surface of base material
The invention provides a method for improving antibacterial activity and biocompatibility of the surface of a base material. Specifically, a common base material is pretreated and then chemically grafted with a polymer chain segment provided by the invention to form a functional surface with surface antibacterial activity. The modified functional surface shows high antibacterial activity to gram-negative bacteria and / or gram-positive bacteria and / or fungi, and meanwhile, the modified functional surface has low hemolytic activity to red blood cells, has excellent cell compatibility to mammalian cells, and shows long-acting antibacterial activity negligible toxicity after in-vivo implantation. Therefore, the modified surface has huge application potential in the field of biomedical materials, and an effective prevention and treatment means is provided for microbial surface infection.
Owner:EAST CHINA UNIV OF SCI & TECH
Pulse and red blood cell concentration monitoring instrument and method
PendingCN106691410AEasy to measureAffect accuracySensorsMeasuring/recording heart/pulse rateComputation complexityRed blood cell
The invention discloses a pulse and red blood cell concentration monitoring instrument which comprises a finger pinching device. An opening is formed in one end of the finger pinching device, a cavity is formed in the finger pinching device, and an infrared light source and a photoelectric detector are oppositely arranged on the upper surface and the lower surface of the cavity respectively. The finger pinching device is connected with a storage and operation device and a display device in sequence. The finger clamping device clamps the finger pad of a testee, after the infrared light source irradiates the finger, original light intensity signals are transmitted, the photoelectric detector receives the original light intensity signals and converts the original light intensity signals into electric signals to collect data within the pixel range, the electric signals are stored in the storage and operation device for storage and processing, and obtained pulse data and red blood cell concentration data are displayed through a display device. According to the pulse and red blood cell concentration monitoring instrument, the signals are collected through the photoelectric detector based on a CMOS camera, detection sensitivity and precision are high, the light intensity signals are processed based on a signal intensity frequency domain modulation method, dicrotic waves can be reduced and even eliminated, and therefore the measurement result is improved. The operation is simple, calculation complexity is greatly reduced, and storage space is saved.
Owner:FOSHAN UNIVERSITY
Artificial heart blood-pump capable of increasing blood pressure step by step
InactiveCN101361994BReduce resistanceAvoid destructionRadial flow pumpsSuction devicesImpellerRed blood cell
Owner:BEIJING UNIV OF TECH
Magnetic and fluid velocity pressure mix suspending mechanical heart blood pump
InactiveCN101244296BImprove the lubrication effectNo wearPump componentsPump installationsMagnetic tension forceImpeller
Owner:BEIJING UNIV OF TECH
Hericium erinaceus glycoprotein with anti-tumor and agglutination activity and preparation method thereof
The invention discloses hericium erinaceus glycoprotein with anti-tumor and agglutination activity and a preparation method thereof, and belongs to the technical field of active protein preparation. The preparation method comprises the following steps: with mycelium prepared by submerged fermentation of hericium erinaceus or sporocarp obtained by a solid cultivation technology as the raw material, separating and purifying to obtain the hericium erinaceus glycoprotein by virtue of steps such as homogenizing and crushing, leaching in cold water, centrifuging, taking liquid supernatant, precipitating ammonium sulfate, carrying out dialysis, and carrying out DEAE (diethyl-aminoethanol)-SepharoseFastFlow column chromatography and the like. Content of polysaccharides in the glycoprotein is 2-20%, and content of protein with a molecular weight range of 10-80KDa is 80-90%. The glycoprotein disclosed by the invention has agglutinating activity on red blood cells, and has a remarkable inhibiting effect on growth of tumor cells such as liver cancer cells, stomach cancer cells and breast cancer cells, and can be used for preparing a possible anti-cancer drug or can be developed into a health product.
Owner:JIANGSU UNIV
Method for evaluating eye irritation by using miniature pig erythrocytes
InactiveCN102359946ASmall batch-to-batch varianceClear genetic backgroundColor/spectral properties measurementsBiological testingFormularyOphthalmology
The present invention discloses an experimental method for evaluating eye irritation by using miniature pig erythrocytes. The method mainly comprises: (1) preparing a suspension of miniature pig erythrocytes; (2) carrying out a miniature pig erythrocyte hemolysis test; (3) carrying out a protein denaturation experiment; (4) predicting a model; (5) carrying out classification and judgment. According to the present invention, the source of the erythrocytes is reliable and safe; the tested material is easy to obtain, and has good uniformity; the test system is simple and cheap, and no special equipment is required; the detection method is rapid, sensitive and universal; the method of the present invention can be directly applicable for safety evaluations of chemicals, cosmetics, pesticides, eye medicines and other substances possibly contacting the eyes, wherein the chemicals comprise surfactants, disinfection products, detergent and the like, the cosmetics comprise shampoo, bath foam, eye cream and the like; the method further can be applicable for rapidly screening, classifying and identifying the eye irritations of the raw materials, the formulas or the products.
Owner:程树军 +1
Image acquiring method and system for detecting single erythrocyte
The invention discloses an image acquiring method and system for detecting a single erythrocyte. The image acquiring method and system uses an automatic viewing and automatic focusing manner when acquiring the image of the single erythrocyte, performs automatic acquisition, automatic screening, and automatic identification on the image of the single erythrocyte, clearly displays the color, the size, the length of the single erythrocyte on a display, and overcomes a time-consuming and labor-consuming defect and person-dependent image acquisition effect of a manual adjusting method.
Owner:GUANGXI NORMAL UNIV
Laser speckle blood perfusion imaging method
InactiveCN109222952AZoom in on small changesMake up for the problem of insufficient calculation accuracySensorsBlood flow measurementRed blood cellPerfusion
The invention relates to a laser speckle blood perfusion imaging method comprising the following steps: 1) obtaining contrast ratio data of each pixel of an original laser image; 2) preprocess that contrast ratio data and converting it into blood flow perfusion amount; 3) mark the blood flow perfusion amount corresponding to different pixel points with different colors. Compared with the prior art, the invention has the advantage of fast equal calculation speed, highlight the region with fast aggregation and aggregation movement of red blood cells, high practicability and popularization.
Owner:SHANGHAI UNIV OF MEDICINE & HEALTH SCI
Peach gum polysaccharide degradation product PGP-1 and preparation method and application thereof
ActiveCN105753998AEasy to makePromote growthDigestive systemMicroorganism based processesDPPHRed blood cell
The invention provides a peach gum polysaccharide degradation product PGP-1.The peach gum polysaccharide degradation product PGP-1, with molecular weight between 1X10<5> and 1X10<6>, contains no neutral polysaccharide and consists of arabinose, xylose, mannose, glucose and galactose in a molar ratio of 0.637:0.054:0.073:0.022:0.556.The peach gum polysaccharide degradation product PGP-1 is simple to prepare and capable of promoting bifidobacterium growth remarkably, inhibiting enterococcus faecium growth remarkably, scavenging hydroxyl free radicals and DPPH free radicals effectively and inhibiting Hela cell growth remarkably; Galectin-3-mediated cell agglutination inhibiting experiments show that the peach gum polysaccharide degradation product PGP-1 is capable of remarkably inhibiting agglutination of chicken blood red blood cells, Hela cells and MCF-7 cells mediated by Galectin-3.
Owner:JINAN UNIVERSITY
Mixer for qi-blood
ActiveCN101347645AGuaranteed blood mixingImprove the mixing effectOther blood circulation devicesMixing methodsEngineeringAngle alpha
The invention discloses a qi and blood mixer, comprising a cylinder body (1) and a cap (2) that is connected with the top of the cylinder body (1); the bottom of the cylinder body (1) is provided with a blood feedback port (3); the cap (2) is provided with a qi and blood mixing passage (6) and an ozone input port (4) and a blood input port (5) which are communicated with the qi and blood mixing passage (6); the communication port between the ozone input port (4) and the qi and blood mixing passage (6) is higher than that between the blood input port (5) and the qi and blood mixing passage (6); the outlet of the qi and blood mixing passage (6) is close to the inner wall of the cylinder body (1) and communicated with the inside of the cylinder body (1); the included angle alpha between the qi and blood mixing passage (6) and the inner wall of the cylinder body (1) is less than 90 DEG. Qi and blood can be mixed in state of normal pressure and maintaining pressure, besides, foam cannot appear when qi and blood are mixed, thus greatly reducing damage of blood erythrocyte and enhancing the effect of qi and blood mixture.
Owner:宁波天益医疗器械股份有限公司
Fast hymen Yegenerating repair medicine
InactiveCN101020046AIncrease elasticityImprove stabilityOrganic active ingredientsPeptide/protein ingredientsTherapeutic effectAmino acid
The fast hymen regenerating and repairing medicine is prepared with hemoglobin 15-30 weight portions, lecithin 10-20 weight portions, amino acid 15-25 weight portions, albumin glue 2-10 weight portions, notoginseng 2-10 weight portions, saffron 1-8 weight portions, protein 5-15 weight portions, cellulose 10-20 weight portions, and free coagulase 5-15 weight portions. The present invention is used in the local targeting process to provide hymen root cell with nutritious components and active growth elements, to activate cells for division and regeneration and to regenerate hymen. The present invention has excellent treating effect.
Owner:闫娜
Coaxial tubular sequestering device for micro spheres and cells
A device for the separation of small particles or cells from a fluid suspension of the same is described. The device includes a coaxial tubular design in which the inner tube is a micro porous tube that allows the passage of liquids and certain particulates up to a certain size cut-off, and the outer tube allows for the collection of passed fluids. Inlet and outlet ports allow the introduction and flushing of components of interest. Embodiments of the device can be used for the separation of blood components, the sequestering of micro spheres used in micro-sphere-based immuno assay, and sample filtration. Other applications are not precluded. Another field of application for this device is in the separation of plasma from red blood cells. The red blood cells will not pass through the membrane due to their size, but plasma will.
Owner:GLOBAL FIA
Composition for promoting iron absorption and application thereof
InactiveCN110881526AImprove absorption and utilization efficiencyIncrease the number ofMilk preparationBiotechnologyRed blood cell
The invention relates to a composition for promoting iron absorption and the application thereof. A functional composition for promoting iron absorption comprises, by weight, 0.04 to 0.1% of lactoferrin and 0.01 to 0.35% of casein glycomacropeptide. The composition can be used in nutritional supplements or dairy products. The composition can improve the absorption and utilization rate of an organism on iron and promote the increase of the number of red blood cells and the content of hemoglobin in blood.
Owner:INNER MONGOLIA YILI INDUSTRIAL GROUP CO LTD
Quantitative detection kit for growth hormone and preparation method of quantitative detection kit
InactiveCN106771265AEasy to storeEasy to transportBiological material analysisBiological testingSerum samplesRed blood cell
The invention discloses a quantitative detection kit for growth hormone. The quantitative detection kit comprises an experimental buffer solution, concentrated washing liquor, an enhancement solution, a coated plate, a standard product, a quality control product and a marker, wherein the enhancement solution is prepared from 1 to 5 mg / L of beta-naphthoyltrifluoroacetone, 15 to 30 mg / L of tri-n-octylphosphine oxide and a third buffer solution; the coated plate is prepared from coating liquid, confining liquid and a reaction plate; the coating liquid is prepared from 1 to 10 ppm of Proclin300, a fourth buffer solution and 1 to 10 [mu]g / ml of a growth hormone monoclonal antibody; the confining liquid is prepared from 1.0 to 10.0 g / L of trehalose, bovine serum albumin with the mass volume ratio of 0.4 to 0.6 percent and the fourth buffer solution; the standard quality and the quality control product are filter paper dried blood pieces; the filter paper dried blood pieces comprise mixtures with 8 concentrations; the mixtures comprise red blood cells, de-hormone negative serum mixed matrixes and the growth hormone; and the marker is prepared from the growth hormone monoclonal antibody and a lanthanide ion chelate according to (1: 1) to (1: 6) m / m. The invention further discloses a preparation method of the kit. The kit disclosed by the invention can ensure that a detection result is highly consistent with a detection result of a serum sample.
Owner:GUANGZHOU FENGHUA BIOENG
Mesoporous bioactive glass/chitosan composite hemostatic sponge and preparation method thereof
ActiveCN112618781AGood biocompatibilityGood hemostatic effectSurgical adhesivesPharmaceutical delivery mechanismRed blood cellPolyvinyl alcohol
The invention discloses mesoporous bioactive glass / chitosan composite hemostatic sponge and a preparation method thereof. The method comprises the following steps of preparing mesoporous bioactive glass by using a bicontinuous microemulsion technology in combination with a sol-gel template method, blending a chitosan solution, a polyvinyl alcohol solution and the mesoporous bioactive glass, performing uniform dispersing, adding a cross-linking agent for a reaction, pouring a reaction product into a mold, performing pre-freezing and molding, and performing freeze-drying to obtain the mesoporous bioactive glass / chitosan composite hemostatic sponge. The composite sponge is simple in preparation process; red blood cells are agglutinated through the combination of polycations of a chitosan material and anions on the surface of a blood red cell membrane, platelet aggregation is activated, and thrombin is activated; the mechanical strength, porosity and water absorption rate of the sponge are improved due to the addition of the mesoporous bioactive glass; when being in contact with a wound, the sponge can rapidly absorb liquid, so that the aggregation of platelets and red blood cells is accelerated, blood clots are rapidly formed and accumulated in a sponge network structure with hierarchical pores, and finally the hemostatic effect is achieved; and the sponge has a good application prospect in the field of hemostatic materials.
Owner:SOUTH CHINA UNIV OF TECH +1
Method for isolating uterine membrane mesenchymal stem cells by dissolving menstrual red blood cells with tea saponin
InactiveCN109182263AHigh activityEffective control of pollutionCell dissociation methodsSkeletal/connective tissue cellsRed blood cellCell culture media
The invention relates to a method for separating uterine membrane mesenchymal stem cells by dissolving menstrual red blood cells with tea saponin, comprising the following steps: (1) preparing reagent: preparing tea saponin solution; 2, obtaining cell precipitation: filtering menstrual blood sample, centrifuging to remove upper plasma to obtain cell precipitation A; adding a tea saponin solution into the cell precipitation A, fully and uniformly mixing the tea saponin solution, removing the supernatant by centrifugation after standing, and obtaining the cell precipitation B; and (3) cell culture: suspending cell precipitate B in a cell culture medium in an incubator for adherent culture, and collecting the third passage cells to be mesenchymal stem cells. As the method adopts tea saponin,the uterine membrane tissue other than the mononuclear obtained by the traditional method can be obtain without damaging the target cells, and the uterine membrane mesenchymal stem cells can be obtainby inducing the mononuclear cells and the uterine membrane tissue from the menstrual blood rapidly and efficiently, and the number is several times of the of the traditional white membrane layer.
Owner:浙江卫未生物医药科技有限公司
Mobile gyromagnetic therapy vehicle
ActiveCN102872535AEasy to moveSpeed up the flowMagnetotherapy using variable magnetic fieldsDiseaseRed blood cell
The invention belongs to the field of medical equipment and particularly relates to a mobile gyromagnetic therapy vehicle. The mobile gyromagnetic therapy vehicle comprises a vehicle body, and is characterized by also comprising a cab and a therapy room, wherein the interior of the therapy room is provided with a single-magnetic head and / or multiple-magnetic head gyromagnetic therapy machine. According to the mobile gyromagnetic therapy vehicle, the gyromagnetic therapy machine is arranged in the vehicle body, thus, the gyromagnetic therapy machine can be conveniently moved to treat patients, is not limited by districts, and can be convenient for treating the patients in time. The actions of the gyromagnetic therapy machine can be fully performed by the mobile gyromagnetic therapy vehicle, i.e. not only can red blood cells be polarized by cell cutting magnetic lines of force to enable viscous blood to smoothly flow but also metabolism is effectively stimulated by bioelectric current to be accelerated, and therefore, the altitude sickness and other traditional diseases are obviously cured.
Owner:淄博思昂健康科技有限公司
Sodium ion corrected erythrocyte hematocrit test system and test method
The invention discloses a sodium ion corrected erythrocyte hematocrit test system and a test method, and the system comprises a sodium ion electrode test unit for measuring the concentration of sodiumions in a blood sample; an impedance test unit for measuring the whole blood impedance of the blood sample; and a calculating unit which is connected with the sodium ion electrode test unit and the impedance test unit and is used for calculating the hematocrit of the blood sample. According to the system, the sodium ion electrode test unit is added to carry out a sodium ion concentration test ina whole blood hematocrit test of an impedance electrode, and the influence of the factor on whole blood impedance is corrected, so that the accuracy of the hematocrit test is improved, and clinical errors are avoided. Meanwhile, the test system is simple in structure, high in test speed, convenient to use, low in price and low in HCT detection cost. The test method is small in error and high in test efficiency and accuracy.
Owner:SHENZHEN CORNLEY BIO MEDICAL CO LTD
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