Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A composite intrauterine device using copper salts as copper ion source

A technology of intrauterine device and composite material, which is applied in the field of composite material intrauterine device, can solve the problem of active oxygen damage to the uterus, and achieve the effect of avoiding damage and excellent contraceptive effect

Inactive Publication Date: 2009-06-24
HUAZHONG UNIV OF SCI & TECH
View PDF7 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The polymer-based composite intrauterine device using elemental copper particles (copper nanoparticles, copper microparticles) as the source of copper ions can well solve the above problems, but the process of oxidizing elemental copper to produce copper ions in the uterine cavity is always Accompanied by the generation of active oxygen, and active oxygen has a damaging effect on the uterus

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A composite intrauterine device using copper salts as copper ion source
  • A composite intrauterine device using copper salts as copper ion source
  • A composite intrauterine device using copper salts as copper ion source

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Weigh 25g CuCl 2 Ultrafine powder, 25g of medical grade low-density polyethylene (LDPE), using methods such as premixing, blending, pressure injection or injection molding, to prepare a γ-shaped composite material IUD.

[0026] Examples 2-27 were all prepared by a method similar to that of Example 1, and the composition of the prepared composite IUD is shown in Table 1.

[0027] Table 1 Composition of composite material IUD in each embodiment

[0028]

[0029]

[0030] The technical effect of using low-density polyethylene as the base material is obviously better than that of using silicone rubber as the base material, so the preferred base material is low-density polyethylene. CuCl 2 、CuSO 4 and Cu(NO 3 ) 2 etc., especially CuCl 2 for the best. Steroidal hormonal contraceptives can use the various progestogens available. Since the melting points of megestrol, norethindrone, and levonorgestrel are higher than the thermal processing temperature of the compo...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a composite material intrauterine contraceptive device using copper salt as a copper ion source. The IUD is made of a mixture of matrix material and active substance and processed into various forms by thermoplastic or thermosetting processing methods, wherein the weight percentage of the active substance is 0.5-50% of the total weight of the composite material IUD, and the matrix material is low-density polyethylene or Silicone rubber, the active substance is one of copper salt or copper salt plus anti-inflammatory and hemostatic drugs and steroid hormone contraceptives. The composite material IUD provided by the present invention not only expands the copper ion source of the copper-containing IUD, but also greatly simplifies the preparation process of the existing bare copper structure IUD, and at the same time ensures excellent contraceptive effect, greatly reducing the clinical cost of the existing bare copper structure IUD. A series of side effects such as hemorrhage and pain exist in the body, and avoid the damage to the uterus caused by the active oxygen generated during the oxidation of elemental copper into copper ions.

Description

technical field [0001] The invention relates to a female long-acting contraceptive and birth control device, specifically a composite intrauterine device with water-soluble copper salt as a copper ion source, which can be loaded with copper salt alone or in combination with copper salt, anti-inflammatory and hemostatic drugs or steroids. Hormonal contraceptives. technical background [0002] Intrauterine Device (IUD) is a safe, effective, economical, reversible and simple contraceptive tool, and it is also one of the most widely used methods in the world. There are two types of IUDs: inert and active. The inert IUD has been completely replaced by the active IUD due to its poor contraceptive effect. There are two main types of active IUDs: copper-loaded IUDs (Cu-IUDs) and extended-release hormonal contraceptive IUDs. Cu-IUD has the advantages of good contraceptive effect, long continuous use time, high cost performance, and reversibility, so it has become the most studied ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61F6/14A61K33/34A61P15/18A61K31/565
Inventor 谢长生蔡水洲夏先平
Owner HUAZHONG UNIV OF SCI & TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com