Artificial pulmonary artery with valve

A technology of artificial lungs and pipelines, which is applied to human tubular structures, blood vessels, medical science, etc., can solve the limitations of clinical application of bovine jugular vein valved pipelines, and there are no substitute products for valved pipelines, venous valve insufficiency, etc. problems, to reduce the risk of various related complications, improve poor biocompatibility, and avoid restenosis

Inactive Publication Date: 2009-12-23
BEIJING BALANCE MEDICAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, because the tensile strength of the bovine jugular vein wall is weaker than that of bovine pericardial tissue, when the pulmonary artery pressure increases, the jugular vein wall often over-expands, resulting in venous valve insufficiency
Due to these reasons, the clinical application of bovine jugular vein valved catheters is limited, and there is no ideal substitute for valved catheters for right ventricular outflow tract implantation.

Method used

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  • Artificial pulmonary artery with valve
  • Artificial pulmonary artery with valve
  • Artificial pulmonary artery with valve

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] refer to figure 1 , is a schematic diagram of the structure of the artificial biological pulmonary artery valved pipeline in Example 1 of the present invention, including a section of bovine jugular vein 3 with three venous valves 4, the bovine jugular vein 3 removes a section with a narrow upper port diameter of the original bovine jugular vein, The artificial biopulmonary valve pipeline also includes two sections of artificial pipelines 1 and 2 made of bovine pericardium material with substantially the same internal diameter as the bovine jugular vein. The valved conduit 3 is clamped in the middle and sutured together with sutures, and the artificial conduits 1 and 2 are adjacent to the venous valve 4 . Wherein, the length between the lower edge of the venous valve of the bovine jugular vein and the lower end edge of the pulmonary artery valved conduit is 2.5-6.5 cm. The whole pipeline is covered with a layer of medical polymer material layer 5 (such as medical polye...

Embodiment 2

[0019] refer to figure 2 , is a schematic diagram of the structure of the artificial biological pulmonary artery valved pipeline in Example 2 of the present invention. In this embodiment, the bovine jugular vein 3 is sutured and connected with a section of artificial pipeline 1' made of the same tissue material, and the vein of the bovine jugular vein 3 The outer surface of the flap is covered with a layer of polymer material 5', and the layer of polymer material 5' has a marking line, which is convenient for doctors to quickly identify the position during operation.

Embodiment 3

[0021] refer to image 3 , is a schematic diagram of the structure of the artificial biological pulmonary artery valved pipeline in Example 3 of the present invention. In this embodiment, the upper and lower ends of the bovine jugular vein 3' are sutured and connected with a section of artificial pipeline 1' and 6 made of artificial polymer materials. Both the artificial conduits 1 ′ and 6 are adjacent to the venous valve 4 . The outer surface of the venous valve 4 of the bovine jugular vein 3' is coated with a polymer material layer 5', and the polymer material layer 5' has a marking line, which is convenient for the doctor to quickly distinguish the position during the operation.

[0022] In each of the above-mentioned embodiments, the bovine pericardial tissue material and the bovine jugular vein have been modified. The method includes rinsing the fresh bovine jugular vein tissue with physiological saline or various tissue infiltration solutions, and using a glutaraldehyde ...

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Abstract

The artificial pulmonary artery with valve includes one section of ox jugular vein with venous valve, and one or two sections of pipes made of artificial material and connected to the ox jugular vein. The artificial pulmonary artery with valve is coated with medical polymer material. The artificial pulmonary artery with valve is superior to available artificial pulmonary artery of ox jugular vein tissue alone, and the latter has the demerits of over reaction, over calcification, etc. The present invention has greatly improved long term treatment effect.

Description

technical field [0001] The invention relates to a substitute of artificial pulmonary artery with valve conduit for reconstructing cardiac outflow tract, in particular to an artificial pulmonary artery with valve conduit for reconstructing human right ventricle-pulmonary artery connection. Background technique [0002] Many complex congenital heart diseases, such as tetralogy of Fallot, pulmonary atresia, double outlet right ventricle, etc., as well as some patients with aortic disease who need Ross operation, need artificial pulmonary artery valve conduit to reconstruct the right ventricle-pulmonary artery A section of valved great vessel channel. Materials commonly used in this type of surgery in the past include autologous pericardium, allogeneic aortic or pulmonary artery conduits, artificial materials such as Gore-tex sheets, and artificially synthesized conduits with valves. Because this type of pipeline substitute is mostly used for infants, there must be a set of bui...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F2/02A61F2/06A61L27/00
Inventor 金磊
Owner BEIJING BALANCE MEDICAL
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