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Medicinal composition for treating impaired glucose tolerance and preparation method thereof

A technology for abnormal glucose tolerance and composition, which is applied in the field of pharmaceutical compositions for the treatment of abnormal glucose tolerance, can solve the problems of hypoglycemia, patient difficulty and the like, and achieves the effects of lowering blood sugar, definite curative effect, and lowering serum triglyceride.

Active Publication Date: 2010-06-02
ZHONGSHI TAILING BEIJING BIO SCI & TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the existing chemical drugs for the treatment of diabetes, such as sulfonylureas, insulin sensitizers, metformin, and α-glucosidase inhibitors, can be used to treat abnormal glucose tolerance, they can easily lead to hypoglycemia, which is unbearable for ordinary patients.

Method used

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  • Medicinal composition for treating impaired glucose tolerance and preparation method thereof
  • Medicinal composition for treating impaired glucose tolerance and preparation method thereof
  • Medicinal composition for treating impaired glucose tolerance and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0116] Weigh raw materials according to the following proportions: 8 parts of dried bitter gourd, 2 parts of mulberry leaves, 1 part of Panax notoginseng, 2 parts of Ligustrum lucidum, 2 parts of Jiaogulan, 0.001 part of chromium picolinate, 0.01 part of zinc gluconate, 0.3 part of dextrin, 0.01 parts of magnesium stearate.

[0117] Preparation:

[0118] (1) Alcohol extraction: Weigh the formula amount of Panax notoginseng and put it into a universal grinder to grind it into 8-10 mesh coarse powder for later use; take the formula amount of dried bitter gourd, privet lucidum, Gynostemma pentaphylla and Panax notoginseng coarse powder into multi-functional extraction In the tank, use 6-10 times the amount of 60-80% ethanol to heat and extract for 1.5 hours, and the extract is filtered through a 120-mesh stainless steel sieve. Filter through a mesh stainless steel sieve, combine the filtrate, send the filtrate to the next process for concentration under reduced pressure, and dis...

Embodiment 2

[0124] Weigh raw materials according to the following proportions: 28 parts of dried bitter gourd, 8 parts of mulberry leaves, 5 parts of Panax notoginseng, 8 parts of Ligustrum lucidum, 8 parts of Jiaogulan, 0.006 parts of chromium picolinate, 0.1 part of zinc gluconate, 1 part of dextrin, 0.08 parts of magnesium stearate.

[0125] Preparation:

[0126](1) Alcohol extraction: Weigh the formula amount of Panax notoginseng and put it into a universal grinder to grind it into 8-10 mesh coarse powder for later use; take the formula amount of dried bitter gourd, privet lucidum, Gynostemma pentaphylla and Panax notoginseng coarse powder into multi-functional extraction In the tank, use 6-10 times the amount of 60-80% ethanol to heat and extract for 1.5 hours, and the extract is filtered through a 120-mesh stainless steel sieve. Filter through a mesh stainless steel sieve, combine the filtrate, send the filtrate to the next process for concentration under reduced pressure, and disc...

Embodiment 3

[0132] Weigh raw materials according to the following proportions: 16.7 parts of dried bitter gourd, 3.3 parts of mulberry leaves, 2.2 parts of Panax notoginseng, 3.3 parts of Ligustrum lucidum, 3.3 parts of Jiaogulan, 0.002 parts of chromium picolinate, 0.07 parts of zinc gluconate, 0.52 parts of dextrin, 0.02 parts of magnesium stearate.

[0133] Preparation:

[0134] (1) Alcohol extraction: Weigh the formula amount of Panax notoginseng and put it into a universal grinder to grind it into 8-10 mesh coarse powder for later use; take the formula amount of dried bitter gourd, privet lucidum, Gynostemma pentaphylla and Panax notoginseng coarse powder into multi-functional extraction In the tank, use 6-10 times the amount of 60-80% ethanol to heat and extract for 1.5 hours, and the extract is filtered through a 120-mesh stainless steel sieve. Filter through a mesh stainless steel sieve, combine the filtrate, send the filtrate to the next process for concentration under reduced p...

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PUM

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Abstract

The invention relates to a medicine combination for treating the impaired glucose tolerance and the preparing method thereof. The medicine combination is mainly composed of balsam pear, mulberry leaf,sanchi, glossy privet fruit, fiveleaf gynostemma herb, chromium picolinate, and zinc gluconate. It is a preparation produced by pharmacological acceptable carrier or excipient, containing capsule, granule, tablet, soft capsule, dropping pill and etc, which is suitable for the patent with impaired glucose tolerance and forepart diabetes. The research indicates that the invention can reduce the blood sugar, decline the insulin resistance, enhance the insulin sensitivity, protect the beta cell function, reduce the serum total cholesterol and serum triglyceride without side and poisonous effects.

Description

1. Technical field [0001] The invention relates to a pharmaceutical composition for treating abnormal glucose tolerance and a preparation method thereof. 2. Background technology [0002] Impaired Glucose Tolerance (IGT) refers to an intermediate state in which the patient's blood sugar is between the blood sugar level of normal people and the blood sugar level of diabetics. At present, it is generally recognized that IGT is the pre-diabetes and a dangerous stage of developing diabetes. With the improvement of people's living standards, the prevalence of abnormal glucose tolerance has increased significantly. WHO announced in 1993 that the prevalence of IGT among adults aged 30 to 64 in the world is mostly 3.0% to 10.0%. In 1996, the standardized prevalence rate of IGT in the national diabetes epidemiological survey was 5.78% in the provincial capital and 3.14% in the poor counties and townships. my country has a population of 1.3 billion. If the IGT prevalence rate is ca...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/48A61K31/455A61K36/605A61K31/704A61K9/16A61K31/191A61P3/10A61K9/20
Inventor 刘铜华
Owner ZHONGSHI TAILING BEIJING BIO SCI & TECH
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