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Chinese traditional medicine tablets for relieving cough and method for preparing the same

A technology of traditional Chinese medicine tablets and ephedra, which is applied in the direction of medical formula, medical preparations containing active ingredients, pill delivery, etc., to achieve the effects of fast absorption, improved bioavailability, and convenient application

Inactive Publication Date: 2008-01-30
GUIZHOU BAIQIANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The object of the present invention is to: provide a Chinese medicine preparation for relieving cough and its preparation method; the present invention aims at the prior art, and the preparation provided increases drug stability, absorbs quickly, improves high bioavailability, is applicable to a wide range of people, and is convenient for patients to take ; It can also cover up the bad smell of medicines to solve the above problems

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0121] Example 1 of the present invention: Sycamore root 300g, Ephedra 250g, Hedyotis diffusa 150g, Saxifraga 150g, Loquat leaf 150g, Mulberry bark 100g, 250g Ephedra was crushed into fine powder, and passed through a 60 mesh sieve (powder extraction rate 90%), 60 After Co radiation sterilization, it is reserved. The remaining five flavors are decocted twice with 8 times the amount of water for 2 hours each time, filtered, concentrated to a relative density of 1.28 (40°C), dried, crushed, and passed through a 60 mesh sieve (yield is about 15%). Mix ephedra fine powder; add 2.5% aspartame and appropriate amount of dextrin, mix, make granules, and dry to obtain granules.

Embodiment 2

[0122] Example 2 of the present invention: sycamore root 300g, ephedra 250g, oldenlandia diffusa 150g, saxifrage 150g, loquat leaf 150g, mulberry bark 100g, pulverize 250g ephedra to fine powder, pass through a 60 mesh sieve (powder extraction rate 90%), 60 After Co radiation sterilization, it is reserved. The remaining five flavors are decocted twice with 8 times the amount of water for 2 hours each time, filtered, concentrated to a relative density of 1.28 (40°C), dried, crushed, and passed through a 60 mesh sieve (yield is about 15%). Ephedra powder and mix well; take PPVP5g and lemon yellow and mix well, take 3 / 5PPVP3g and paste powder and mix well. Use 1.5% K30 anhydrous ethanol as a binder, 40 mesh material, granules, and the remaining 2 / 5 PPVP 2g mixed with lemon yellow mixed powder is added to the prepared granules and compressed to obtain dispersible tablets .

Embodiment 3

[0123] Example 3 of the present invention: Sycamore root 300g, ephedra 250g, oldenlandia diffusa 150g, saxifrage 150g, loquat leaf 150g, mulberry bark 100g, pulverize 250g ephedra to fine powder, pass 60 mesh sieve (powder extraction rate 90%), 60 After Co radiation sterilization, it is reserved. The remaining five flavors are decocted twice with 8 times the amount of water for 2 hours each time, filtered, concentrated to a relative density of 1.28 (40°C), dried, crushed, and passed through a 60 mesh sieve (yield is about 15%). Mix ephedra fine powder; add appropriate amount of starch, use 60% ethanol and 2% soybean oil to make soft material, the soft material is made of pellets machine-made pellets, the wet material is squeezed through a 0.8mm sieve, the strip wet granules are cut and rounded , 50~60℃ dry molding, pass through 16~20 mesh sieve, select pellets, then pellets can be obtained.

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Abstract

The present invention discloses a cough-relieving traditional Chinese medicine tablet and the preparation method, and the invention is the tablet which contains 300g of phoenix tree root, 250g of ephedra herb, 150g of spreading hedyotis herb, 150g of saxifrage, 150g of loquat leaf and 100g of white mulberry root-bark, furthermore, 40g of microcrystalline cellulose and 1g of magnesium stearate are added for preparation. The tablet provided by the present invention has good disintegration, high dissolution degree of the active ingredients and fast effect, thus improving the bioavailability of the drug and enhancing the efficacy of the drug markedly.

Description

[0001] This application is a divisional application of the invention patent application filed by the applicant on October 26, 2005, titled: "A Chinese Medicinal Preparation for Cough Relief and Its Preparation Method", and the application number is 200510200647X. Technical field: [0002] The invention relates to a Chinese medicine tablet for relieving cough and a preparation method thereof, and belongs to the technical field of Chinese medicine. Background technique: [0003] At present, there are many kinds of cough medicines, but most of them are western medicines, which are prone to side effects when taken. However, the effect of Chinese medicine to relieve cough is not ideal, and it is inconvenient to take, which brings a lot of trouble to patients. In order to achieve the purpose of treatment, many inventors and pharmaceutical companies have done a lot of research and provided some treatment products; For example, ZL 02134145. 1, the name "cough capsule and its preparation p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/748A61K9/28A61K47/38A61P11/14
Inventor 张之君
Owner GUIZHOU BAIQIANG PHARMA
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