Intravital residual activity insulin algorithm

Abstract

The invention relates to an algorism of residual active insulin in a human body, which enables the algorism to share higher compatibility through building up a quick-effective or short-lived insulin pharmacodynamics curve diagram data base, and to contain more crowds and have more reliable numerical result through the detailed classification of the data base. The invention is quantitatively described through the gross area under the total antihypelipidemic activity PD (pharmacodynamics) curve diagram of extrinsic insulin, the residual antihypelipidemic activity of one time point after dosing can be quantitatively described by the rest area under curve after the time point, which is more convenient and direct, and then the relationship curve of residual quick-effective or short-lived active insulin and time is calculated, namely the percentage curve of residual quantity on each time point, and the algorism is more scientific and accurate. Doctors or patients can easily receive the residual quantity of active insulin in patients' body in current time according to the interval time between the current time and last administration time, matching with the relationship curve of residual quick-effective or fugitive active insulin and time.

Description

technical field [0001] The invention relates to the technical field of insulin dosage control, in particular to an algorithm for residual active insulin in the body. Background technique [0002] Diabetes is a chronic disease that endangers the health of the social population. Its degree of harm ranks third among all diseases and continues to increase. Practice has proved that insulin is the most effective drug for controlling blood sugar and preventing various serious complications. Since the human body's demand for insulin is expressed in two forms: a continuous basal amount and a relatively large dose (supplementary amount) after a meal, insulin injection therapy is also designed for this characteristic. The traditional injection method is manual injection, that is, clinicians or patients manually inject long-acting or ultra-long-acting insulin once a day to meet the basic needs of the human body for insulin. In addition, short-acting or fast-acting insulin is administer...

AI Technical Summary

Problems solved by technology

What patients need to supplement before meals is mainly conventional or quick-acting (ultra-short-acting) insulin. If the possible residual activity of the insulin used last time is not considered when calculating the dosage, due to the superposition of the dosage and residual activity this time, it is likely to cause hypoglycemic excessive, resulting in hypoglycemia

[0006] However, the calculation of residual active insulin is a very professional and complicated work, let alone patients, even full-time medical staff are often difficult to complete

Because it is too difficult, in clinical practice or in actual application, patients generally rely on experience to simply calculate the amount of residual active insulin in the body according to several fixed linear ratios. Often the error is large, and blood sugar control is subject to certain restrictions.

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