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Chinese traditional medicine composite for depressive neurosis, preparation method and application thereof

A neurosis and composition technology, applied in the field of traditional Chinese medicine preparations, can solve the problems of large anticholinergic side effects, high drug price, unsuitability for popularization and application, etc., and achieves the effects of good curative effect, low treatment cost, and easy popularization and use.

Inactive Publication Date: 2008-06-25
董建国
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, tricyclic antidepressants are the first choice for the treatment of depressive neurosis, such as imipramine, doxepin, amitriptyline, etc., but these drugs have large anticholinergic side effects, such as dry mouth and difficulty urinating , constipation and other symptoms; there are also tetracyclic antidepressants represented by maprotiline, which are effective and have few side effects, but the price of the drug is quite high, so it is not suitable for popularization and application

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Jieyu Anshen Capsule for the treatment of depressive neurosis: Take 16 parts of Bupleurum Atractylodes Rhizoma Atractylodes Rhizome 22 parts White Peony 22 parts Angelica 15 parts Poria Cocos 32 parts Coptis 12 parts Fried Zaoren 32 parts Baiziren 16 parts Raw Ground 16 parts Chenpi 12 parts Magnolia officinalis 10 parts 12 parts Pinellia 12 parts Polygala 13 parts Keel 32 parts Oyster 32 parts Chuanxiong 22 parts Mint 7 parts Licorice 12 parts Cinnabar 7 parts Ginger 2 parts, all raw materials are mixed and crushed into fine powder, put into No. 2 capsule.

Embodiment 2

[0019] The composition of raw materials is 10 parts of Bupleurum, 12 parts of Bai Shao, 12 parts of Angelica, 10 parts of Poria, 22 parts of Coptidis, 6 parts of fried jujube kernels, 25 parts of Baiziren, 13 parts of raw land, 8 parts of tangerine peel, 8 parts of magnolia, 6 parts of pinellia, 7 parts of polygala, 10 parts of keel 25 parts oyster 26 parts Chuanxiong 15 parts mint 5 parts licorice 6 parts ginger 1 part cinnabar 4 parts.

[0020] Others are the same as embodiment 1.

Embodiment 3

[0022] The composition of raw materials is 20 parts of Bupleurum, 28 parts of Bai Shao, 26 parts of Angelica, 18 parts of Poria, 36 parts of Coptidis, 15 parts of fried jujube kernels, 35 parts of Baiziren, 18 parts of raw land, 15 parts of Magnolia officinalis, 15 parts of pinellia, 12 parts of polygala, 15 parts of keel 36 parts of oysters, 35 parts of Chuanxiong, 26 parts of peppermint, 8 parts of licorice, 13 parts of ginger, 2 parts of cinnabar, and 8 parts of cinnabar. Others are the same as in Example 1.

[0023] Effect example

[0024] Case inclusion criteria: (1) Chinese Classification and Diagnostic Criteria for Mental Disorders (CCMD-3); (2) Hamilton Depression Scale (HAMD, 24 items) > 20 points; (3) symptoms lasted for at least 2 weeks; (4) excluded Depression caused by organic diseases, physical diseases, and psychoactive substances, and patients have symptoms such as auditory hallucinations and delusions, which have been differentiated from schizophrenia.

[002...

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PUM

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Abstract

The invention belongs to the field of a Chinese traditional medicine preparation and in particular relates to a Chinese traditional medicine combination for curing depressive neurosis as well as a preparation method and application thereof.The ingredients composition of the combination are: Chinese thorowax root of 10-20 proportion, atractylodes ovata of 10-30 proportion, white peony root of 10-30 proportion, Chinese angelica root of 8-20 proportion, indian bread of 20-40 proportion, coptis root of 4-20 proportion, jujube kernel of 20-40 proportion, Chinese arborvitae kernel of 10-20 proportion, fresh rehmannia root of 10-20 proportion, dried tangerine peel of 5-18 proportion, magnolia officinalis of 5-20 proportion, pinellia of 5-15 proportion, thinleaf milkwort root of 8-20 proportion, dragon bone of 20-40 proportion, oyster of 20-40 proportion, szechwan lovage rhizome of 10-30 proportion, mint of 3-10 proportion, liquorice of 5-15 proportion, vermilion cinnabar of 3-10 proportion, fresh ginger of 1-2 proportion.According to clinical verification, the Chinese traditional medicine combination has the advantages of safety and no side effects, good treating effects, effectiveness rate of over 99 per cent and lasting medicine potency as well as low cost of the adopted components, low curing expense and the invention is convenient for promoting to be used among the patients with the depressive neurosis.

Description

(1) Technical field [0001] The invention belongs to the field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine composition for treating depressive neurosis, as well as its preparation method and application. (2) Background technology [0002] Depressive neurosis, also known as neurotic depression, is a neurosis characterized by persistent depression caused by social and psychological factors, often accompanied by anxiety, physical discomfort and sleep disturbance. Patients have treatment requirements, but There were no obvious motor inhibition or psychotic symptoms, and life was not seriously affected. This disease is commonly known as "dysthymia" internationally. In 1982, the prevalence of this disease was 3.1%. In recent years, with the increasingly fierce social competition and accelerated pace of life, the prevalence rate has risen to 5.2%. According to the Department of Psychiatry of West China Medical Universit...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/14A61K9/16A61K9/20A61K9/48A61P25/24A61K33/28A61K35/02A61K35/56A61K35/618
Inventor 董建国
Owner 董建国
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