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Externally-applied medicinal composition for treating surgical wound and preparation of ointment thereof

A technology for externally-applied medicines and compositions, applied in the field of pharmaceutical compositions and their preparation, can solve the problems of difficulty in obtaining materials for wounds and wound musculocutaneous flaps, poor third-degree burn effects, and easy infection, and achieve excellent wound healing effects. , Super skin healing function, the effect of promoting normal tissue growth

Inactive Publication Date: 2008-09-17
吴振林
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disadvantage of the above-mentioned traditional Chinese medicine is that the powder will stick to the wound, and it needs to be cleaned when changing the dressing, which will easily cause bleeding and pain. ), Huang Dan (containing lead), etc. have certain toxicity to the human body
The disadvantage of this method is that the myocutaneous flap transplantation will cause new damage to the patient, and it is difficult to obtain the material of the myocutaneous flap when the wound in a special part or the wound is too large, and there are too many tissue defects. , often requiring a second surgery
The disadvantages of these medicines are that the tincture will irritate the wound surface and make the pain worse; the scab affects the drainage of the wound and easily leads to infection; the anti-infection effect of the ointment is weak, and the effect on the third-degree burn with a deep wound is not good
However, because the normal tissue of about 1 cm needs to be turned over, the exposed phalanx has to be bitten off or sawed off. In this way, the patient's finger is shortened and the defect of the injured finger is aggravated, which will affect the appearance and future of the patient's finger. Life
[0009] To sum up, at present, there is still a lack of a clinical treatment that can cure all kinds of wounds at various stages, antibacterial and antibacterial, and promote the growth of normal tissues, grow flesh and skin, do not irritate wounds, and do not corrode normal tissues. Good and non-toxic external drug to human body

Method used

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  • Externally-applied medicinal composition for treating surgical wound and preparation of ointment thereof
  • Externally-applied medicinal composition for treating surgical wound and preparation of ointment thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0062] Embodiment 1: the preparation of ointment

[0063] (1) Take each raw material according to the following proportions, and roughly grind frankincense, myrrh, catechin, dried blood, and keel into medicinal powder:

[0064] 30 grams of comfrey, 40 grams of angelica, 35 grams of honeysuckle, 15 grams of frankincense, 15 grams of myrrh, 18 grams of catechu, 20 grams of blood, 20 grams of keel, 100 grams of beeswax, and 600 grams of sesame oil.

[0065] (2) Soak comfrey, honeysuckle, angelica dahurica and sesame oil in the same pot for 24 hours, heat to 130°C, keep for 10 minutes, and remove the medicinal residues.

[0066] (3) Heat the remaining liquid to 135°C, add frankincense, myrrh, catechin, dried blood, and keel, keep for 5 minutes, and filter with gauze;

[0067] (4) Add beeswax to the filtrate and stir until it melts, then let it cool naturally.

Embodiment 2

[0068] Embodiment 2: the preparation of oil agent

[0069] (1) Take each raw material according to the following proportions, and roughly grind frankincense, myrrh, catechin, dried blood, and keel into medicinal powder:

[0070] 45 grams of comfrey, 25 grams of Angelica dahurica, 20 grams of honeysuckle, 5 grams of frankincense, 5 grams of myrrh, 9 grams of catechu, 9 grams of blood, 9 grams of keel, and 500 grams of peanut oil.

[0071] (2) Soak comfrey, honeysuckle, angelica dahurica and peanut oil in the same pot for 24 hours, heat to 120°C, keep for 20 minutes, and remove the medicinal residues.

[0072] (3) Heat the remaining liquid to 140°C, add frankincense, myrrh, catechin, dried blood, and keel, continue heating for 10 minutes, and filter with gauze.

[0073] (4) The filtrate can be cooled naturally.

Embodiment 3-8

[0075] The recipes and proportions of Examples 3-8 are shown in the table below, and the preparation method is the same as that of Example 1. Wherein, the formulations of Examples 6 and 8 are emulsions, and all the others are ointments. All embodiments can complete the object of the present invention and realize the effect of the present invention.

[0076] Embodiment 3-8 sees the following table:

[0077]

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PUM

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Abstract

The invention discloses a medicine composition for surgical-wound, comprising materials in the following weight ratio: lithospermum 30 to 45 shares, angelica 25 to 40 shares, stem of Lonicera japonica 20 to 35 shares, olibanum 5 to 15 shares, myrrh 5 to 15 shares, catechu 8 to 18 shares, dragon's blood 10 to 20 shares, keel 10 to 20 shares, beeswax 0 to 100 shares and vegetable oil 400 to 600 shares. The invention also relates to a preparation method, which means that the materials are weighted proportionally; the lithospermum, stem of Lonicera japonica, angelica and vegetable oil are all put into a boiler to immersing for 24 hours, heated to 120 to 130 DEG C and kept for 10 to 20 minutes before fishing out dregs of decoctions. The residual fluid is then heated to 130 to 140 DEG C and added olibanum, myrrh, catechu, dragon's blood and keel powder to blend evenly and at last filtered by gauges before holding for 5 to 15 minutes. The beeswax is added into the filtered fluid and then cooled naturally. The medicine is used fir curing different surgical-wounds.

Description

technical field [0001] The invention relates to a pharmaceutical composition and a preparation method thereof, in particular to an external pharmaceutical composition for treating surgical wounds and a preparation method of the ointment. Background technique [0002] Skin wounds and injuries are common clinical diseases in surgery, such as burns, various traumas, skin ulcers, mucosal injuries, etc., all belong to surgical wounds. Surgical wounds usually have a long course of disease, great pain, and are prone to concurrent infection. [0003] In clinical practice, for fresh wounds (such as knife wounds, gunshot wounds, bruises, etc.), Western medicine usually uses 2% hydrogen peroxide and saline to clean the wound, 0.5% iodophor to disinfect, and then use sterile gauze or vaseline gauze to clean the wound. cover. This method is generally only suitable for wounds with small wounds, but it is not effective for wounds with large wounds or wounds with irregular edges that cann...

Claims

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Application Information

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IPC IPC(8): A61K36/889A61K9/06A61K47/44A61P17/02A61K35/02A61K35/64A61K35/644
Inventor 吴振林
Owner 吴振林
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