Al technical title is built by PatSnap Al team. It summarizes the technical point description of the patent document.
A technology of single-sided acupuncture and medicinal materials, which is applied in the field of medicine, can solve the problems of rare and few studies on the active ingredients of single-sided acupuncture medicinal materials.
Active Publication Date: 2008-09-17
ZHUZHOU QIANJIN PHARMA
View PDF0 Cites 7 Cited by
Summary
Abstract
Description
Claims
Application Information
AI Technical Summary
This helps you quickly interpret patents by identifying the three key elements:
Problems solved by technology
Method used
Benefits of technology
Problems solved by technology
[0005] Single-sided acupuncture is not a standard medicinal material issued by the Pharmacopoeia and the Ministry. It is rare to use this medicinal material in current Chinese patent medicines, and there is no Chinese
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more
Image
Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
Click on the blue label to locate the original text in one second.
Reading with bidirectional positioning of images and text.
Smart Image
Examples
Experimental program
Comparison scheme
Effect test
Embodiment 1
[0033] The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention. Embodiment 1 single sided needle medical material for testing sample
[0034] Zanthoxylum dissitum Hemsl. is the dry root and stem of Zanthoxylum dissitum Hemsl. The medicinal materials were provided by Hunan Zhuzhou Qianjin Pharmaceutical Co., Ltd., a total of 30 batches, numbered 1, 2, 3, ..., 28, 29, 30. See Table 1:
[0035] Table 1 Single-sided needle medicinal materials for testing samples
[0036] sample number
Embodiment 2
[0037] The preparation of embodiment 2 test samples
[0038] After the medicinal materials are crushed, pass through a 40-mesh sieve, take 1.0g of each batch of medicinal medicinal powders, accurately weigh them, put them in a 50ml round bottom flask, add 30ml of petroleum ether, heat and reflux for 30min, discard the petroleum ether liquid, evaporate the residue to dry up the solvent, and add Methanol 30ml was heated and refluxed twice, each time for 1h, filtered while hot, combined twice, evaporated to dryness, the residue was dilute to 2ml with methanol, used as the test solution, and filtered through a 0.45μm microporous filter before HPLC analysis. Membrane filtration.
Embodiment 3
[0039] The selection of embodiment 3 reference object
[0040] After the single-sided needle medicinal material was extracted by the above method, multiple chromatographic peaks appeared through HPLC analysis. Since there is no standard product for the exclusive component of single-sided needle, a stable Appearing chromatographic peaks (Peak No. 6, R t 34min) as a reference (structure has not yet been identified) for fingerprint analysis and evaluation, after systematic comparative analysis, it is proved that this method is feasible.
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
PUM
Property
Measurement
Unit
Fineness
aaaaa
aaaaa
Login to view more
Abstract
The invention relates to a discrimination method of Zanthoxylum dissitum Hemsl medical material, comprising establishing HPLC standard fingerprint of Zanthoxylum dissitum Hemsl medical material; measuring the fingerprint of the measured sample of the Zanthoxylum dissitum Hemsl medical material using the same method and comparing the fingerprint of the measured sample of the Zanthoxylum dissitum Hemsl medical material and the standard fingerprint of Zanthoxylum dissitum Hemsl medical material to screen the qualified Zanthoxylum dissitum Hemsl medical material in line with the standard fingerprint of Zanthoxylum dissitum Hemsl medical material. The process of establishing the HPLC standard fingerprint of Zanthoxylum dissitum Hemsl medical material comprises: preparing the sample solution and acquiring the HPLC standard fingerprint of Zanthoxylum dissitum Hemsl medical material by determing the common fingerprint features by comparing the fingerprintsof 30 batches of the Zanthoxylum dissitum Hemsl medical material at the conditions that: chromatographic column: Kromasil RP-C18 4.6mm*250mm, 5um; mobile phase: acetonitrile-0.2%triethylamine phosphate solution; using gradient elution: 0 min-10min-30min-70min; the ratio by volume of acetonitrile and 0.2%triethylamine phosphate solution is 5:95-10:90-10:90-40:60; detection wave:280nm. The invention provides a new method for quality control and discrimination of the Zanthoxylum dissitum Hemsl medical material.
Description
technical field [0001] The invention relates to the field of medicine, in particular to a method for identifying medicinal materials of single-sided needles. Background technique [0002] The modernization of traditional Chinese medicine is one of the most popular research directions in the development of contemporary traditional Chinese medicine, and has become a hot spot in the medical circles at home and abroad. Among them, the modernization of quality standards for Chinese medicinal materials and proprietary Chinese medicines is an important part of the modernization of Chinese medicines. Due to the wide variety of Chinese herbal medicines, the different medication habits in different regions, the simple records of ancient herbal medicines, misrepresentation and misuse, and the evolution of medicines, etc., the confusion of Chinese herbal medicines with different names, homonyms and different substances, and genuine and non-genuine products are very serious. More genera...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
Application Information
Patent Timeline
Application Date:The date an application was filed.
Publication Date:The date a patent or application was officially published.
First Publication Date:The earliest publication date of a patent with the same application number.
Issue Date:Publication date of the patent grant document.
PCT Entry Date:The Entry date of PCT National Phase.
Estimated Expiry Date:The statutory expiry date of a patent right according to the Patent Law, and it is the longest term of protection that the patent right can achieve without the termination of the patent right due to other reasons(Term extension factor has been taken into account ).
Invalid Date:Actual expiry date is based on effective date or publication date of legal transaction data of invalid patent.
Login to view more