Compound ofloxacin injection for fowl and preparation method thereof

Abstract

The invention discloses an avian compound ofloxacin injection and a preparation method thereof, which aims at providing the avian compound ofloxacin injection that has rapid onset of action for the treatment for avian colibacillosis, effectivity, high efficiency and can ease the diseased avian stress reactions, treat both manifestation and root cause of disease, reduce the times and dosage of drugfor being taken and reduce occurrence of the residual drugs exceeding the standards, and the preparation method that has simple technology and easy realization. Each 100l injection contains: 0.5 to 5kg of the ofloxacin, 3 to 15kg of neomycin sulfate, 0.2kg of sodium bisulfite, 500 to 2000ml of hydrochloric acid, 0.01kg of EDTA-2Na and 0.06kg of dexamethasone sodium phosphate. By adopting a compound preparation which combines anti-bacterial drugs and antibiotics for usage, and the combining usage of the ofloxacin, the neomycin sulfate and the dexamethasone sodium phosphate, the injection of the invention has rapid onset of action for avian colibacillosis, effectivity and high efficiency and can significantly ease the clinical symptoms caused by avian colibacillosis, treat both manifestation and root cause of disease, prevent the secondary infection and increase the weight of birds.

Description

technical field [0001] The invention relates to a compound ofloxacin injection for poultry and a preparation method thereof. Background technique [0002] Chicken colibacillosis is a common disease of chickens, including Escherichia coli air sac inflammation, sepsis, salpingitis, peritonitis and other types, which bring great losses to the chicken industry. Escherichia coli is one of the resident bacteria in the intestinal tract of chickens. It has a certain function of assisting digestion. The pathogenic ones account for 10-15% of the total number of bacteria. They usually do not get sick. When the environment changes, they can cause disease. And it is contagious. It mainly pollutes the surrounding environment and spreads through feces excretion, causing chicken infection, and can be secondary to other infections, with a high mortality rate. [0003] The medicines currently used for the treatment of colibacillosis in chickens, such as ofloxacin and neomycin sulfate, are ma...

AI Technical Summary

Problems solved by technology

Due to absorption problems and bacterial resistance and sensitivity reduction, the therapeutic effect is reduced when used alone, and some even have no therapeutic effect, and some may cause other diseases due to secondary infection

However, in order to treat diseases, farmers increase the dosage of drugs or prolong the use time, and the drug residues exceed the standard.