Compound niacin norfloxacin injection for animals and preparation thereof
A technology of norfloxacin nicotinic acid and injection, applied to medical preparations containing active ingredients, pharmaceutical formulas, digestive system, etc., can solve bacterial drug resistance and sensitivity reduction, increase drug dosage, and improve therapeutic effect reduce the secretion of gastrointestinal glands, reduce the frequency and dose of medication, and reduce the chance of drug resistance
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Embodiment 1
[0022] (1) Weigh 1 kg of norfloxacin nicotinate and put it into 10 L of water for injection, stir for 10-25 min, and completely dissolve until clear.
[0023] (2) Put 10kg of lincomycin hydrochloride into 30L of water for injection, stir for 10-25min, and dissolve it completely until clear, then add 0.05kg of atropine sulfate, 0.2kg of sodium sulfite, and 0.01kg of EDTA-2Na in sequence, and stir until completely dissolved .
[0024] Add the solution prepared in step 1 and step 2 to 100L of water for injection, stir evenly, keep for 15-20min, and prepare the veterinary compound norfloxacin nicotinic acid injection of the present invention after the liquid is clear.
Embodiment 2
[0026] (1) Weigh 1.5kg of norfloxacin nicotinic acid into 15L of water for injection, stir for 10-25min, and completely dissolve until clear.
[0027] (2) Put 9kg of lincomycin hydrochloride into 30L of water for injection, stir for 10-25min, and dissolve it completely until clear, then add 0.06kg of atropine sulfate, 0.2kg of sodium sulfite, and 0.01kg of EDTA-2Na in sequence, and stir until completely dissolved .
[0028] Add the solution prepared in step 1 and step 2 to 100L of water for injection, stir evenly, keep for 15-20min, and prepare the veterinary compound norfloxacin nicotinic acid injection of the present invention after the liquid is clear.
Embodiment 3
[0030] (1) Weigh 4 kg of norfloxacin nicotinic acid and put it into 25 L of water for injection, stir for 10-25 min, and completely dissolve until clear.
[0031] (2) Put 5kg of lincomycin hydrochloride into 25L of water for injection, stir for 10-25min, and dissolve it until clear, then add 0.3kg of atropine sulfate, 0.2kg of sodium sulfite, and 0.01kg of EDTA-2Na in sequence, and stir until completely dissolved .
[0032] Add the solution prepared in step 1 and step 2 to 100L of water for injection, stir evenly, keep for 15-20min, and prepare the veterinary compound norfloxacin nicotinic acid injection of the present invention after the liquid is clear.
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