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Medicine composition for treating Tourette syndrome and its preparation method

A technology of Tourette and composition, which is applied in the direction of drug combination, pharmaceutical formula, medical preparation containing active ingredients, etc.

Inactive Publication Date: 2008-11-19
北京陛辰中医门诊部
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At the same time, there is no Chinese patent medicine specifically for the treatment of Tourette syndrome in China

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0112] Embodiment 1: the preparation of capsule

[0113] Uncaria 30kg, Iris 30kg, Oyster 20kg, Magnet 20kg, Scorpion 10kg

[0114] Coptidis 10kg Papaya 30kg Stretch Grass 80kg Magnolia 40kg Chrysanthemum 40kg

[0115] Take the above-mentioned raw materials, add enough water to Shichangpu and Magnolia Magnolia, steam distillation, collect volatile oil for about 8 hours, and store the obtained volatile oil and water in separate containers; Combine tendon grass and chrysanthemum, add water to decoct twice, add 10 times the amount of water each time, decoct for 2 hours, mix the decoction with the aqueous solution after extracting the volatile oil, and concentrate to a clear paste with a relative density of 1.05-1.10 at 50°C; Add 60% ethanol to Uncaria chinensis and Coptidis Rhizome, add 60% ethanol to reflux and extract twice, add 4 times the amount of alcohol each time, reflux for 1 hour, filter the alcohol liquid, recover ethanol from the filtrate, combine the remaining liquid ...

Embodiment 2

[0116] Embodiment 2: the preparation of tablet

[0117] Uncaria 70kg, Iris 70kg, Oyster 60kg, Magnet 60kg, Scorpion 20kg

[0118] Coptidis 25kg Papaya 70kg Stretch Grass 115kg Magnolia Magnolia 70kg Chrysanthemum 70kg

[0119] Take the above raw materials, add 5 times the amount of water to Shichangpu and Magnolia Magnolia, and collect the volatile oil by steam distillation until the extraction rate of the volatile oil is significantly reduced, separate the volatile oil, and store the water liquid in another device; the obtained volatile oil and beta cyclodextrin and Mix water at a ratio of 1ml: 5g: 70ml, stir at 75°C for 1 hour, refrigerate for about 18 hours, filter, and dry at low temperature to obtain the beta-cyclodextrin inclusion complex of volatile oil; dregs and oyster . Clear ointment with a density of 1.05 to 1.10; reflux extraction of Uncaria and Coptis Rhizoma with 90% ethanol for 4 times, adding 8 times the amount of alcohol each time, refluxing for 2 hours, fi...

Embodiment 3

[0120] Embodiment 3: the preparation of granule

[0121] Uncaria 40kg, Iris 40kg, Oyster 45kg, Magnet 45kg, Scorpion 14kg,

[0122] Coptidis 18kg Papaya 50kg Stretch Grass 105kg Magnolia 60kg Chrysanthemum 60kg

[0123]Take the above raw materials, crush Shichangpu and Magnolia Magnolia into coarse particles, add 6 times the amount of water, steam distillation for 8 hours, collect the volatile oil for later use, store the aqueous solution in another device, and prepare the dregs for later use; mix the above volatile oil with beta-cyclodextrin and water Mix at a ratio of 1ml: 6g: 80ml, stir at 80°C for 1 hour, refrigerate for 24 hours, filter, and dry at low temperature to obtain the beta-cyclodextrin inclusion complex of volatile oil, which is set aside; oysters, magnetite Add 8 times the amount of water and fry for 20 minutes, then combine with the extracted oil dregs, scorpion, papaya, chinensis, and chrysanthemum, add water and cook 3 times, add 10 times the amount of wate...

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PUM

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Abstract

The invention discloses a medicinal combination used for curing gilles de la tourettes syndromes, and a method for preparing the medicinal combination, which belongs to the field of a Chinese traditional medicine. The medicinal combination is prepared from uncaria, japanese sweetflag, oyster, magnet, scorpion, coptis, pawpaw, club moss, magnolia flower, chrysanthemum, and so on. Effective ingredients are extracted through wet distillation, decoction in water, or in ethanol and so on based on the different characteristics of the medicaments. Capsules, tablets, granules, powder, pills or oral are prepared in this way. The medicinal combination has the function of calming the endopathic wind and resolving phlegm, which shows specific and safe curative effects for gilles de la tourettes syndromes of children. The invention further discloses a method used for controlling the quality of the medicinal combination.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a traditional Chinese medicine composition for treating Tourette's syndrome, a preparation method and a quality control method thereof. It belongs to the field of traditional Chinese medicine. Background technique [0002] Tourette's syndrome (TS), also known as Tourette's syndrome (TS), is a neuropsychiatric disorder characterized by chronic multiple motor tics accompanied by vocal tics with onset in childhood. The etiology and pathogenesis of this disease are not yet fully understood. It is generally believed that it is related to many aspects such as genetic factors, central neurotransmitter imbalance, psychological factors, and environmental factors. It may be a syndrome caused by the interaction of multiple factors during development. [0003] TS syndrome can occur in various races, social classes and cultural backgrounds, and is a worldwide disease. TS syndrome has been rep...

Claims

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Application Information

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IPC IPC(8): A61K36/888A61P25/00A61K33/26A61K35/56A61K35/64G01N30/02G01N30/90A61K35/618A61K35/646
Inventor 刘弼臣
Owner 北京陛辰中医门诊部
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