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Patch

A patch and patch device technology, applied in the field of skin patches or plaster, can solve problems such as limiting material selection

Inactive Publication Date: 2008-12-03
NAMIBIA MEDICAL INVESTMENTS (PTY) LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, DMF is also a solvent for many synthetic materials and permeates a large number of other materials, two factors that limit the choice of materials available for making patches suitable for administering DMF or DMF-containing compositions to human or animal patients

Method used

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Experimental program
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Embodiment Construction

[0050] Reference is now made to the drawings, wherein like reference numerals are used to designate like parts.

[0051] As shown, the transdermal delivery patch 1 comprises a skin adhesive coated support layer 3 and a peelable cover sheet 4 . The peelable cover sheet 4 can be removed to expose the proximal layer 5 of the patch. As indicated above, the surface of the skin adhesive coating of the support layer 3 may be in the form of a commercially available skin-compatible adhesive product as described in WO98 / 55157, which includes cohesive reinforcement Components and at least one of the following ingredients: dry adhesive components, such as polyisobutylene; moisture absorbing wet adhesive components such as hydrocolloid powder; and preservatives such as pectin and / or antimicrobial agents, the adhesive is characterized in Polyreinforcement components include polysiloxanes.

[0052] On the adhesive-coated support layer 3 is mounted the pressure-vulcanized or injection-molde...

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PUM

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Abstract

The invention provides a patch device adapted for use in the transdermal administration to a patient of a composition including one or more pharmaceutically, cosmetically, pesticidally, prophylactically, and nutritionally active substance, the patch consisting of a layered construct adapted to be adhered to the skin of a patient and defining a cavity for receiving one or more disruptable containers of the composition or components of the composition to be administered between a proximal layer and a distal layer thereof, which proximal layer is adapted in use to be located in intimate contact with the skin of the patient and which distal layer is in use disposed on the outer side thereof, wherein the proximal layer is partially permeable to that composition, so that in use the integrity of the one or more containers may be disrupted thereby causing the composition to be disposed in the cavity and permeate from there through the proximal layer to be absorbed through the skin into the body of the patient. The invention further provides a method of applying an irritant to the skin of a user.

Description

technical field [0001] The present invention relates to a skin patch or plaster for delivering pharmaceutically active substances or compositions containing such active substances to the skin of a human or animal organism. Background technique [0002] It is well known in the art of drug delivery that certain pharmaceutical actives can be administered dermally to a patient in need thereof. It is also well known in the art that many pharmaceutically active substances are not per se suitable for such dermal administration because they are not easily absorbed through the skin or cause skin irritation when applied directly to the skin. It is also well known in the art that, in some cases, the absorption of these substances through the patient's skin can be facilitated by the use of various excipients for the preparation of pharmaceutical formulations and especially by the use of well known penetration enhancer substances. However, it is further known in the art that some known ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/70A61K31/16
CPCA61K31/16A61K9/703
Inventor 昆顿·范罗伊恩克里斯蒂娜·范罗伊恩约翰内斯·琼斯亚伯拉罕·乔舒亚·勒鲁科尼利厄斯·约翰内斯·鲍威尔
Owner NAMIBIA MEDICAL INVESTMENTS (PTY) LTD