Vladimiria root extract, composition containing the vladimiria root extract and use thereof

A technology of sichuan wood incense and extract, which is applied in the field of sichuan wood incense extract, can solve the problems of low content of dehydro wood odoriferone and wood alkane lactone, inability to accurately determine drug efficacy, unclear composition, and the like, To achieve the effect of simple preparation method, avoid rebound increase of gastric acid secretion, and reduce recurrence rate

Inactive Publication Date: 2009-06-10
CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Abstract
  • Description
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  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The above-mentioned documents and patent documents have reported that the dehydrocresinolide in Chuanxiang has the pharmacological effect of inhibiting or indirectly inhibiting experimental gastric ulcer; The derivatives are used for the treatment of ulcers or canker diseases; but the cost of extracting the monomers of dehydrocresinolide and cosmanthinolide from Chuanxiang, or preparing their derivatives is very high, but by The content of deh

Method used

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  • Vladimiria root extract, composition containing the vladimiria root extract and use thereof
  • Vladimiria root extract, composition containing the vladimiria root extract and use thereof
  • Vladimiria root extract, composition containing the vladimiria root extract and use thereof

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Embodiment 1

[0031] Embodiment 1: the preparation of the extract of Akiras sichuanensis of the present invention

[0032] A. Take Chuanxiang and pulverize it, and extract it by supercritical fluid extraction; or

[0033] Weighing and pulverizing Akiras chinensis, and extracting by solvent ultrasonic extraction, the concentration of ethanol used is 30% to 95%; or

[0034] Weighing and pulverizing Chuanxiang, and extracting by solvent percolation extraction, the concentration of ethanol used is 30% to 95%; or

[0035] Weighing and pulverizing Akiras chinensis, extracting by solvent reflux extraction method, the concentration of ethanol used is 30%-95%;

[0036] B. Take the solvent extract prepared in step A, recover the solvent under reduced pressure, add water to suspend, extract and separate the organic solvent, recover the organic solvent under reduced pressure, and then dry under reduced pressure to obtain the Akiras sinensis extract of the present invention.

[0037] The supercritical...

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Abstract

The invention relates to a vladimiria root extract belonging to medicament field, especially to an extract from vladimiria root used to treat ulcer diseases. The extract using medicinal vladimiria root as material is prepared by: extracting by supercritical fluid or alcohols solvent, suspending by water, extracting by nonpolar organic solvent and separating, collecting the organic phase part and drying. The extracting method in the invention can achieves vladimiria root extract with stable controllable quality, can make the cost largely lower than the single compound preparation. The exact prepared by the process of the invention achieves evident curative effect for treating ulcer diseases, and provides another selection for treating ulcer diseases in clinic.

Description

technical field [0001] The invention relates to an extract of Akira sinensis. Specifically, it is prepared by extracting A. siberiana as a raw material, which can be used to prepare a treatment for ulcer disease, and belongs to the field of medicine. Background technique [0002] Most peptic ulcers occur in the stomach or duodenum, referred to as ulcer disease for short. The clinical manifestations are mainly abdominal pain, which is limited to the upper abdomen. It has three characteristics: chronic, periodic and rhythmic. Ulcer disease is a common disease in internal medicine. The data show that the incidence rate is as high as 20%, and the disease course is long, repeated and changeable, and complications are common, which seriously affects people's work and quality of life. Effective medicines for treating ulcers in traditional Chinese medicine, such as Chenxianglu Bailu Tablets, Weilikang Tablets, etc., Western medicines such as Ranitidine Capsules, Losec Capsules, etc...

Claims

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Application Information

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IPC IPC(8): A61K36/289A61K9/08A61K9/10A61K9/14A61K9/16A61K9/20A61K9/48A61P1/04A61K125/00
Inventor 赖先荣孟宪丽张艺
Owner CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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