Vladimiria root extract, composition containing the vladimiria root extract and use thereof

Abstract

The invention relates to a vladimiria root extract belonging to medicament field, especially to an extract from vladimiria root used to treat ulcer diseases. The extract using medicinal vladimiria root as material is prepared by: extracting by supercritical fluid or alcohols solvent, suspending by water, extracting by nonpolar organic solvent and separating, collecting the organic phase part and drying. The extracting method in the invention can achieves vladimiria root extract with stable controllable quality, can make the cost largely lower than the single compound preparation. The exact prepared by the process of the invention achieves evident curative effect for treating ulcer diseases, and provides another selection for treating ulcer diseases in clinic.

Description

technical field [0001] The invention relates to an extract of Akira sinensis. Specifically, it is prepared by extracting A. siberiana as a raw material, which can be used to prepare a treatment for ulcer disease, and belongs to the field of medicine. Background technique [0002] Most peptic ulcers occur in the stomach or duodenum, referred to as ulcer disease for short. The clinical manifestations are mainly abdominal pain, which is limited to the upper abdomen. It has three characteristics: chronic, periodic and rhythmic. Ulcer disease is a common disease in internal medicine. The data show that the incidence rate is as high as 20%, and the disease course is long, repeated and changeable, and complications are common, which seriously affects people's work and quality of life. Effective medicines for treating ulcers in traditional Chinese medicine, such as Chenxianglu Bailu Tablets, Weilikang Tablets, etc., Western medicines such as Ranitidine Capsules, Losec Capsules, etc...

AI Technical Summary

Problems solved by technology

[0007] The above-mentioned documents and patent documents have reported that the dehydrocresinolide in Chuanxiang has the pharmacological effect of inhibiting or indirectly inhibiting experimental gastric ulcer; The derivatives are used for the treatment of ulcers or canker diseases; but the cost of extracting the monomers of dehydrocresinolide and cosmanthinolide from Chuanxiang, or preparing their derivatives is very high, but by The content of dehydrocosmolide and cosmolide extracted from Chuanxiang is extremely low

At present, there is no relevant report on the preparation of dehydrocorylides and coylides by synthetic methods.

In view of the complex composition of Chinese herbal medicines, the ingredients that exert the medicinal effects of the medicine are not clear, and it is not possible to accurately determine the efficacy of the medicine only by discovering a single ingredient or part of it.

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