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Medicament for treating idiopathic edema and preparation method thereof

A technology for a drug and an API is applied in the field of drugs for the treatment of idiopathic edema and its preparation, and can solve the problems of unclear pathogenesis and the like

Active Publication Date: 2011-09-14
HEBEI YILING MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the unknown etiology and pathogenesis, there is no targeted drug used in clinical practice

Method used

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  • Medicament for treating idiopathic edema and preparation method thereof
  • Medicament for treating idiopathic edema and preparation method thereof
  • Medicament for treating idiopathic edema and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0279] The preparation of pharmaceutical capsule of the present invention (tentatively named: Guiling Xiaozhong Capsule):

[0280] prescription:

[0281] Angelica 200g Bupleurum 133g Poria 267g Alisma 160g

[0282] Atractylodes macrocephala 160g Polyporus 160g Motherwort 400g Eupatorium 160g

[0283] 160 grams of white peony, 133 grams of Cyperus, 133 grams of cassia twig

[0284] Preparation:

[0285] a) Weigh the selected Atractylodes Rhizoma Atractylodes Rhizome, Guizhi, Cyperus Cyperi, and Eupatorium in proportion, add 8 times the amount of water, soak for 1 hour, extract the volatile oil by steam distillation for 5 hours, collect the volatile oil in another device, and the oil yield is not less than 0.25%; filter the extract, concentrate under reduced pressure until the relative density measured at 60°C is 1.05, and set aside;

[0286] b) Weigh the cleaned Motherwort, Poria cocos, and Polyporus umbilicalis in proportion and add water to extract 3 times, add 13 times t...

Embodiment 2

[0293] The preparation of pharmaceutical tablet of the present invention:

[0294] prescription:

[0295] Angelica 186g Bupleurum 144g Poria 248g Alisma 172g

[0296] Atractylodes macroporus 149g Polyporus 154g Motherwort 413g Eupatorium 145g

[0297] 161 grams of white peony, 128 grams of Cyperus 145 grams of cassia twig

[0298] Preparation:

[0299] a) Weigh the selected Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizome, Guizhi, Rhizoma Cyperi, and Eupatorium in proportion, add 6-10 times the amount of water, soak for 0.5 hours, extract the volatile oil by steam distillation for 4 hours, collect the volatile oil in another device, and the oil yield is not high. Less than 0.25%; the extract is filtered, concentrated under reduced pressure until the relative density measured at 60°C is 1.0, and set aside;

[0300] b) Weigh the selected Leonurus, Poria cocos, and Polyporus in proportion and add water to extract 3 times, add 10-15 times the amount of water for ...

Embodiment 3

[0307] The preparation of medicinal powder of the present invention:

[0308] prescription:

[0309] Angelica 240g Bupleurum 160g Poria 212g Alisma 192g

[0310] Atractylodes macroporus 126g Polyporus 126g Motherwort 482g Zeeland 192g

[0311] 126 grams of Radix Paeoniae Alba, 159 grams of Rhizoma Cyperi, 105 grams of Guizhi

[0312] Preparation:

[0313] a) Weigh the selected Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizome, Guizhi, Rhizoma Cyperi, and Eupatorium in proportion, add 6-10 times the amount of water, soak for 2 hours, extract the volatile oil by steam distillation for 7 hours, collect the volatile oil in another device, and the oil yield is high Less than 0.25%; the extract is filtered, concentrated under reduced pressure until the relative density measured at 60°C is 1.1, and set aside;

[0314] b) Weigh the selected motherwort, tuckahoe, and polyporus in proportion, add water and extract 3 times, add 15 times the amount of water for the first ...

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Abstract

The invention provides a medicament for treating idiopathic edema and a preparation method thereof. The medicine contains pure natural plant drugs of angelica, radix bupleuri, atractylis ovata, Alismaorientale, radix paeoniae alba, tuckahoe, grifola, rhizoma cyperi, motherwort, trumpetweed, cassia twig, and the like. In the medicament, the angelica breaks extravesated blood, nourishes new blood and relaxes vain to eliminate dampness; radix bupleuri, tuckahoe and Alisma orientale soothes liver and strengthens spleen for inducing diuresis to alleviate edema; the atractylis ovata, grifola, and the like, invigorates qi and strengthens the spleen, clears damp and promotes diuresis and blood circulation, and recuperates the body function; the plant drugs are combined to free liver qi and strengthen the spleen, smooth collaterals, avoid moisten, and eliminate edema, so as to ensure the effect of sooth liver and strengthen spleen, smooth collaterals and induce diuresis. Research shows that the medicament has the pharmacological actions of inducing diuresis, reducing capillary permeability, improving microcirculatory disturbance and increasing immunologic function, and the like, treats idiopathic edema etiologically and semeiologically, and has the advantages and characteristics of multiple levels and treatment on principal and subordinate of traditional Chinese medicine.

Description

technical field [0001] The invention relates to a medicine for treating idiopathic edema and a preparation method thereof, belonging to the technical field of Chinese herbal medicine preparations. Background technique [0002] Idiopathic edema (Idiopathic Edema) refers to a group of clinical syndromes of unknown etiology characterized by weight gain and general edema. The disease is common in women of childbearing age, and the age of onset is 30-40 years old. It is rarely seen in women before menarche and postmenopause. The main clinical manifestations are abdominal distension with non-inflammatory eyelid, face, hands and lower extremity edema, characterized by postural fluid retention. In addition, the disease is often accompanied by symptoms of autonomic nervous disorders such as nervousness, irritability, and headaches, and may also be combined with indigestion, menstrual disorders, obesity, and diabetes. Due to the unknown etiology and pathogenesis, there is currently ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8905A61K9/20A61K9/48A61K9/14A61K9/10A61K9/02A61K9/12A61K9/00A61P7/10
Inventor 吴以岭许红辉李晓燕姬雪礼张永锋孟学强李向军郑立发王猛秦拢
Owner HEBEI YILING MEDICINE INST
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