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Application of medicine combination in preparing medicament for reducing insulin resistance

A technology of insulin resistance and composition, applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the problem of large side effects

Active Publication Date: 2009-11-11
北京中一堂科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, long-term use of these drugs has relatively large side effects

Method used

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  • Application of medicine combination in preparing medicament for reducing insulin resistance
  • Application of medicine combination in preparing medicament for reducing insulin resistance
  • Application of medicine combination in preparing medicament for reducing insulin resistance

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0162] Bupleurum 600g, Paeoniae Alba 600g, Citrus aurantium 600g, Rhubarb 200g, Scutellaria baicalensis 600g, Coptis 200g

[0163] The 6 medicinal materials were extracted twice with 10 times their weight of water, each time for 1.5 hours. The extract was filtered, concentrated under reduced pressure to 1:1, added 90% ethanol to 65% alcohol content, filtered, concentrated under reduced pressure to form a thick paste. Vacuum drying at 75°C to make dry paste powder.

Embodiment 2

[0165] Bupleurum 600g, Paeoniae Alba 600g, Citrus aurantium 600g, Rhubarb 240g, Scutellaria baicalensis 600g, Coptis 480g

[0166] The 6 medicinal materials were extracted twice with 10 times their weight of water, each time for 1.5 hours. The extract was filtered, concentrated under reduced pressure to 1:1, added absolute ethanol until the alcohol content was 75%, filtered, concentrated under reduced pressure to form a thick paste. Vacuum drying at 85°C to make dry paste powder.

Embodiment 3

[0168] Bupleurum 540g, Paeoniae Alba 900g, Citrus aurantium 540g, Rhubarb 180g, Scutellaria baicalensis 540g, Coptis 300g

[0169] The 6 medicinal materials were extracted twice with 10 times their weight of water, each time for 1.5 hours. The extract was filtered, concentrated under reduced pressure to 1:1, added 95% ethanol to 70% alcohol content, filtered, concentrated under reduced pressure to form a thick paste. Vacuum drying at 80°C to make dry paste powder.

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Abstract

The invention relates to an application of a medicine combination in preparing a medicament for reducing insulin resistance. The medicine combination comprises the following raw medicinal materials by weight portion: 3-30 of bupleurum, 3-15 of peony roots, 3-15 of citrus aurantium, 1-6 of rhubarb, 3-15 of scutellaria, and 1-12 of coptis roots.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to the application of a pharmaceutical composition in the preparation of medicines for treating diabetes. Background technique [0002] Diabetes mellitus is a chronic progressive lifelong disease caused by the disorder of sugar, protein and fat metabolism in the body, which is characterized by hyperglycemia and glucosuria. The disease can lead to heart and kidney complications, blindness and amputations. In recent years, it has been clinically observed that the incidence of diabetes is increasing year by year. At present, there are about 150 million diabetics in the world, and the number of diabetics in my country has exceeded 40 million. Among the diabetic cases, a few are insulin-dependent diabetes (type I), and most are non-insulin-dependent diabetes (type II). Most people with diabetes need life-long medication. [0003] Most patients with type II diabetes are obe...

Claims

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Application Information

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IPC IPC(8): A61K36/752A61K36/8888A61P3/10
Inventor 仝小林
Owner 北京中一堂科技有限公司