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Traditional Chinese medicine composition used for treating melancholia

A composition and depression technology, applied in the directions of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the problems such as lack of clear standard for the content of functional ingredients such as monarch medicine, lack of clinical test verification of effect, and inability to guarantee quality stability, etc. Significant curative effect, small toxic and side effects

Active Publication Date: 2010-01-20
BEIJING TONGRENTANG HEALTH PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above two patented formulas are not supported by the theory of traditional Chinese medicine. They are simply patchwork and accumulation of many Chinese herbal medicines. There is no clear standard for the content of the active ingredients such as monarch medicine. The quality stability cannot be guaranteed, and the effect lacks the verification of clinical trials.

Method used

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  • Traditional Chinese medicine composition used for treating melancholia

Examples

Experimental program
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Effect test

Embodiment 1

[0025] Embodiment 1: A kind of Zhiyu Anshen Granule

[0026] Components: Weigh 800g of Hypericum perforatum, 800g of Bupleurum, 600g of fried gardenia, 600g of turmeric, 1000g of Albizia juniper, and 600g of polygala (licorice).

[0027] Preparation method: The above hypericum perforatum is extracted twice with 70% ethanol under reflux. Add 10 times the amount for the first time, add 8 times the amount for the second time, reflux for 2 hours each time, combine the extracts, filter, recover ethanol under reduced pressure (50-70°C, 0.06-0.08MPa) and concentrate to a relative density of about 1.10 (60°C) extract, dried under reduced pressure to obtain dry extract powder. Turmeric plus 80% ethanol reflux extraction twice, each 8 times the amount, each 1 hour, combined extracts, filtered, dregs standby, filtrate decompression recovery ethanol, and concentrated (50-70 ° C, 0.06-0.08 MPa) to a relative density of about 1.10 (60°C), for later use. Bupleurum bupleurum, fried gardeni...

Embodiment 2

[0028] Embodiment 2: a kind of Zhiyu Anshen Pill

[0029] Components: Weigh 400g Hypericum perforatum, 1200g Bupleurum bupleuri, 300g fried gardenia, 900g turmeric, 500g bark of Albizia juniperus, 900g Polygala (licorice broiled).

[0030] Preparation method: the above hypericum perforatum is extracted 3 times with 60% ethanol under reflux. Add 9 times the amount for the first time, add 10 times the amount for the second time, add 8 times the amount for the third time, reflux for 2.5 hours each time, combine the extracts, filter, and recover ethanol under reduced pressure (50-70 ° C, 0.06-0.08 MPa) and concentrated to an extract with a relative density of about 1.15 (60° C.), dried under reduced pressure to obtain dry extract powder. Turmeric plus 90% ethanol reflux extraction twice, each 8 times the amount, each 1 hour, combined extracts, filtered, dregs for subsequent use, filtrate decompression recovery ethanol, and concentrated (50-70 ° C, 0.06-0.08 MPa) to a relative de...

Embodiment 3

[0031] Embodiment 3: A kind of Zhiyu Anshen tablet

[0032]Components: Weigh 1200g of Hypericum perforatum, 400g of Bupleurum, 900g of fried gardenia, 300g of turmeric, 1500g of acacia bark, and 300g of licorice-roasted polygala (licorice-roasted).

[0033] Preparation method: the above Hypericum perforatum is extracted twice with 80% ethanol under reflux. Add 10 times the amount for the first time, add 8 times the amount for the second time, reflux for 2 hours each time, combine the extracts, filter, recover ethanol under reduced pressure (50-70°C, 0.06-0.08MPa) and concentrate to a relative density of about 1.10 (60°C) extract, dried under reduced pressure to obtain dry extract powder. Turmeric plus 70% ethanol reflux extraction 3 times, each 9 times the amount, each 1.5 hours, combined extracts, filtered, dregs standby, filtrate decompression recovery ethanol, and concentrated (50-70 ° C, 0.06-0.08 MPa) to a relative density of about 1.10 (60°C), for later use. Bupleurum...

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Abstract

The invention discloses a traditional Chinese medicine composition used for treating melancholia, comprising the following raw material medicines: 4-12 parts of hypericum perforatum by weight, 4-12 parts of radix bupleuri by weight, 3-9 parts of stir-fried gardenia by weight, 3-9 parts of radix curcumae by weight, 5-15 parts of silktree albizzia bark by weight and 3-9 parts of licorice moxibustion senega by weight. The traditional Chinese medicine composition has the effects of calming the liver, relieving the depressed liver, reducing fever, relieving restlessness, tranquilizing and allaying excitement and is used for the light and moderate melancholia belonging to people with stagnation of qi and fire transmission. The symptoms comprise mental depression, vexation, discomposure, impatience, testiness, chest distress, costal swelling, insomnia, amnesia, reddened tongue and vein weakness.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating depression and its preparation. Background technique [0002] At present, mental illness has become a prominent social problem all over the world. As a serious mental disorder, depression ranks fourth in the world's top ten common diseases. The incidence of depression in my country is also increasing year by year. In addition, from the perspective of disease burden, depression has accounted for 6.2% of the entire disease burden. Therefore, no matter from the perspective of disease spectrum, incidence rate and social significance, research and development of drugs for the treatment of depression is a top priority. [0003] The main manifestations of depression are: restlessness, irritability, chest tightness and hypotension, insomnia, forgetfulness, sluggish expression, weight loss, suicidal tendencies, unwarranted guilt, etc. [0004] Modern medicine believes that the e...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/16A61P25/24
Inventor 张宏查圣华
Owner BEIJING TONGRENTANG HEALTH PHARMA
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