Active extract for sanwei sandalwood as well as extraction method and medical application thereof

A technology for extract and sandalwood, which is applied to the active extract of three-flavor sandalwood and its extraction method and the field of medical use, can solve the problems of unclear effective components, no availability, imperfect quality monitoring means, etc.

Inactive Publication Date: 2010-02-03
QINGHAI UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The preparation method is simple, the extraction process is simple, no extract with concentrated active ingredients is obtained, and the active ingredients are unclear, the content of active ingredients is unclear, and the quality control methods are not perfect

Method used

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  • Active extract for sanwei sandalwood as well as extraction method and medical application thereof
  • Active extract for sanwei sandalwood as well as extraction method and medical application thereof
  • Active extract for sanwei sandalwood as well as extraction method and medical application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0157] A 000 Extract preparation:

[0158] Extraction of active ingredients from nutmeg:

[0159] Step 1. Take nutmeg raw medicinal material, use cream making machine to make cream and oil, and make nutmeg cream and nutmeg oil.

[0160] Step 2, the cream obtained in step 1 is extracted with 5 times the amount of 70% ethanol and cold-soaked overnight, the 70% ethanol extract is decompressed to recover ethanol, and the extract is steamed until it has no alcohol smell; add an appropriate amount of water to the aqueous extract, and put it on a HPD100 large scale Pore ​​resin; then wash with 90% ethanol and 60% ethanol successively, the resulting 60% ethanol washing solution is concentrated to be the total phenolic acids of myristic acid, and the obtained 90% ethanol washing solution is concentrated to be the total lignans of myristicum.

[0161] Step 3, take nutmeg oil, and extract volatile oil with steam distillation to obtain nutmeg volatile oil.

[0162] Extraction of active...

Embodiment 2

[0167] The preparation of embodiment 2 pharmaceutical compositions

[0168] The obtained nutmeg and sandalwood volatile oil (sampled according to the ratio of 1:1 of the original medicinal materials, and converted according to the extraction rate) were first ground with β-hydroxypropyl cyclodextrin (adding about 10% of the original three-flavored sandalwood medicinal materials), and adding water for about Grind 5ml until the volatile oil smells light; then add 90% and 60% extracts of nutmeg and extracts extracted from jujube (both sampled according to the ratio of 1:1 of the original medicinal materials, and converted according to the extraction rate), and then add polyvinylpyrrolidone K30 ( Less than 4% of the final solvent), vitamin C (approximately equivalent to 0.2% of the original Sanwei sandalwood medicinal material), add an appropriate amount of water to grind, add water to the final solvent, and obtain a suspension.

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PUM

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Abstract

The invention relates to an active extract for sanwei sandalwood as well as an extraction method and a medical application thereof. The extract comprises the following active components of medicaments: fructus choerospondiatis total flavonoids, fructus choerospondiatis total phenolic acid, nutmeg total lignans, nutmeg total phenolic acid, sandalwood volatile oil and nutmeg volatile oil.

Description

Technical field: [0001] The invention relates to the fields of processing, extraction and preparation of Tibetan medicine; specifically, the invention relates to the active extract of sandalwood with three flavors and its extraction method and medical application. Background technique: [0002] Coronary atherosclerotic heart disease, referred to as coronary heart disease or coronary heart disease, is sometimes called coronary artery disease. Heart disease caused only by myocardial ischemia and hypoxia due to narrowing or obstruction of the coronary artery atherosclerosis. Since more than 90% of ischemic heart disease is caused by coronary atherosclerosis, the WHO announced the two as synonyms. Coronary heart disease is one of the main health killers in China at present. Statistics show that every year, 42 patients die of coronary heart disease in every 105 patients who die. [0003] Drugs for the treatment of coronary heart disease include nitrates, β-receptor blockers, c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/22A61P1/14A61P3/04A61P3/06A61P9/12A61P17/16A61P31/04A61P35/00A61P37/04A61P39/06A23L1/30A23L33/105
CPCA23V2002/00
Inventor 格日力王金辉徐成魏玉海杨梅申旭霁张蕾
Owner QINGHAI UNIVERSITY
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