Active extract for sanwei sandalwood as well as extraction method and medical application thereof
A technology for extract and sandalwood, which is applied to the active extract of three-flavor sandalwood and its extraction method and the field of medical use, can solve the problems of unclear effective components, no availability, imperfect quality monitoring means, etc.
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Embodiment 1
[0157] A 000 Extract preparation:
[0158] Extraction of active ingredients from nutmeg:
[0159] Step 1. Take nutmeg raw medicinal material, use cream making machine to make cream and oil, and make nutmeg cream and nutmeg oil.
[0160] Step 2, the cream obtained in step 1 is extracted with 5 times the amount of 70% ethanol and cold-soaked overnight, the 70% ethanol extract is decompressed to recover ethanol, and the extract is steamed until it has no alcohol smell; add an appropriate amount of water to the aqueous extract, and put it on a HPD100 large scale Pore resin; then wash with 90% ethanol and 60% ethanol successively, the resulting 60% ethanol washing solution is concentrated to be the total phenolic acids of myristic acid, and the obtained 90% ethanol washing solution is concentrated to be the total lignans of myristicum.
[0161] Step 3, take nutmeg oil, and extract volatile oil with steam distillation to obtain nutmeg volatile oil.
[0162] Extraction of active...
Embodiment 2
[0167] The preparation of embodiment 2 pharmaceutical compositions
[0168] The obtained nutmeg and sandalwood volatile oil (sampled according to the ratio of 1:1 of the original medicinal materials, and converted according to the extraction rate) were first ground with β-hydroxypropyl cyclodextrin (adding about 10% of the original three-flavored sandalwood medicinal materials), and adding water for about Grind 5ml until the volatile oil smells light; then add 90% and 60% extracts of nutmeg and extracts extracted from jujube (both sampled according to the ratio of 1:1 of the original medicinal materials, and converted according to the extraction rate), and then add polyvinylpyrrolidone K30 ( Less than 4% of the final solvent), vitamin C (approximately equivalent to 0.2% of the original Sanwei sandalwood medicinal material), add an appropriate amount of water to grind, add water to the final solvent, and obtain a suspension.
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