Method for improving dispersivity of grease-contained traditional Chinese medicinal granules in water

Abstract

The invention relates to a method for improving the dispersivity of grease-contained traditional Chinese medicinal granules in water, which comprises the following steps: adding a surfactant equivalent to the concentrated solution solid content of 0.1-8 percent by weight into a concentrated solution after extracting and concentrating grease-containing traditional Chinese medicinal water, stirring to dissolve, uniformly mixing, then preparing traditional Chinese medicinal extract powder by adopting a spray drying process, and preparing the traditional Chinese medicinal granules through pelletization, wherein the HLB value of the surfactant is 7-11, and the surfactant comprises hydroxylated lecithin, polysorbate and octaacetyl sucrose. The prepared granules have good dispersivity. The method has simple operation, is easy for realizing industrial production, is used for improving the dispersivity of the grease-contained traditional Chinese medicinal granules when poured and dissolved by water, improves the compliance of patients and the accuracy of administration dosage and ensures clinical curative effect. The method can also improve the bulk density of the traditional Chinese medicinal extract powder and be convenient for the successful implementation of working procedures including subsequent pelletization, packaging and the like.

Description

(1) Technical field [0001] The invention relates to a method for improving the water dispersibility of fat-containing traditional Chinese medicine formula granules. It belongs to the technical field of traditional Chinese medicine formula granules. (2) Background technology [0002] Traditional Chinese medicine formula granules are standardized and standardized single-flavor traditional Chinese medicine granules made under the guidance of traditional Chinese medicine theory, using standardized processing and processing of traditional Chinese medicine decoction pieces as raw materials, and adopting modern pharmaceutical technologies such as scientific extraction, low-temperature concentration, instant drying and granulation. [0003] Chinese medicinal materials (fruits, seeds, etc.) containing more oily components are extracted with water, concentrated and dried, and the Chinese medicinal extract powder made from them has strong hydrophobicity. The water surface or adhered t...

AI Technical Summary

Problems solved by technology

[0003] Chinese medicinal materials (fruits, seeds, etc.) containing more oily components are extracted with water, concentrated and dried, and the Chinese medicinal extract powder made from them has strong hydrophobicity. The water surface or adhered to the wall of the device will affect the patient's compliance with the drug and the accuracy of the dosage, thereby affecting the clinical efficacy

At present, there is a lack of research on improving the dispersibility of such varieties in water in the field of traditional Chinese medicine formula granules