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Biorhythm information acquisition method

A technology of biorhythms and physiologically active substances, applied in biomaterial analysis, sensors, diagnosis, etc., to achieve simple and invasive effects

Inactive Publication Date: 2012-03-14
SONY CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Incidentally, Patent Document 1 does not describe specific tissues (or cells) to be collected or specific genes to be measured

Method used

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Experimental program
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Effect test

Embodiment Construction

[0027] 1. Biological rhythm information acquisition method

[0028] In order to establish a method for obtaining information about biological rhythms of individual living beings simply and in a minimally invasive manner, the present inventors paid attention to tears and saliva, which are biological samples that can be collected in an extremely minimally invasive manner . It is known that tears contain 60 or more physiologically active substances. The physiologically active substances include: proteins such as lactoferrin, lysozyme, secretory IgA (sIgA), which are used for resistance to infectious diseases; and TSP (prealbumin specific to tears), such as vitamin A, which is used for As a carrier of fat-soluble substances. In addition, saliva contains various physiologically active substances, for example, digestive enzymes such as amylase, glycoproteins such as lactoferrin, mucin, etc., lipids, and vitamins.

[0029] The present inventors analyzed changes in the secreted amo...

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Abstract

Disclosed herein is a method of acquiring information on a biorhythm on the basis of a variation with time of the quantity of a physiologically active substance in tear and / or saliva, wherein the physiologically active substance may be a secretory immunoglobulin A antibody, and the information can be acquired based on a variation with time of the quantity of the secretory immunoglobulin A antibody in the tear and / or the saliva, and lysozyme is further used as the physiologically active substance, and the information is acquired based on a variation with time of the ratio of the quantity of the secretory immunoglobulin A antibody to the quantity of lyzozyme ((quantity of secretory immunoglobulin A) / (quantity of lysozyme)) in the tear and / or the saliva.

Description

technical field [0001] The present invention relates to a method of acquiring information on biological rhythms of individual living beings. More specifically, the present invention relates to a method of acquiring information on circadian rhythm based on changes over time in the amounts of physiologically active substances in tears and saliva. Background technique [0002] It is known that various biological phenomena in individual living things each exhibit a "periodic rhythm" that oscillates independently. Periodic rhythms are called "biorhythms". In particular, "circadian rhythm" having a cycle of about one day generally controls rhythms observed in biological phenomena such as sleep-wake rhythm and daily change rhythms of body temperature, blood pressure, and amounts of secreted hormones. In addition, it is known that the circadian rhythm is related to the degree of mental and physical activity, exercise capacity, drug allergy, and the like. [0003] Biological rhyt...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/00
CPCG01N2333/924G01N33/573G01N33/6854
Inventor 早川智广山本拓郎中川和博相马温彦山下志功王凡安田章夫
Owner SONY CORP