Adinandra nitida leaf flavone oral tablet and preparation method
A technology of flavonoids and bright leaves of poplar leaves, applied to medical preparations containing active ingredients, pharmaceutical formulas, medical preparations with no active ingredients, etc., can solve the problems of low development and utilization of poplar leaves of bright leaves
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Embodiment 1
[0011] Weigh 100g of poplar leaves, add 10 times the amount of water, heat and decoct, boil for 30 minutes, vacuum filter while hot, add 10 times the amount of water to the filter residue, heat and boil for 30 minutes, then filter while hot, combine the two filtrates and cool After reaching room temperature, some crystallization will be found on the wall and bottom of the container. Transfer the filtrate to a refrigerator at 0°C for 5 hours, then centrifuge at 1000rpm for 30 minutes to separate the pale yellow-green precipitate, and place the precipitate in an oven at 85°C. Dry for 1 hour, then add 10g of sucrose, 1g of citric acid, and 1g of dextrin, mix evenly, spray water as the binder and place it in a fluidized bed granulator for granulation. The size of the particles should pass through a 16-mesh sieve. After adding 0.3g of magnesium stearate to the prepared granules, use a rotary tablet machine to process them into round oral tablets. The weight of each tablet is control...
Embodiment 2
[0013] Weigh 100g of poplar leaves, add 30 times the amount of water, heat and decoct, boil for 30 minutes, vacuum filter while hot, add 30 times the amount of water to the filter residue, heat and boil for 30 minutes, then filter while hot, combine the two filtrates and cool After reaching room temperature, some crystallization will be found on the wall and bottom of the container. Transfer the filtrate to a refrigerator at 4°C for 8 hours, then centrifuge at 5000rpm for 10 minutes to separate the pale yellow-green precipitate, and place the precipitate in an oven at 100°C. Dry for 1 hour, then add 30g of sucrose, 2g of citric acid, 5g of dextrin, and 3g of gum arabic, mix evenly, spray water as the binder and place it in a fluidized bed granulator for granulation. It is advisable to use a mesh sieve. After adding 0.3g of magnesium stearate to the prepared granules, they are processed into oral tablets with circular and bright-leaved poplar plant patterns with a rotary tablet ...
Embodiment 3
[0015] Weigh 0.5 kg of poplar leaves, add 50 times the amount of water, heat and decoct, boil for 60 minutes, vacuum filter while hot, add 50 times the amount of water to the filter residue, heat and boil for 60 minutes, then filter while hot, and combine the two filtrates After cooling to room temperature, some crystallization will be found on the container wall and the bottom of the container. Transfer the filtrate to a refrigerator at 4°C for 10 hours, then centrifuge at 5000rpm for 30 minutes to separate the pale yellow-green precipitate, and place the precipitate in an oven at 100°C After drying for 1 hour, add 100 g of sorbitol, 50 g of glucose, 25 g of citric acid, 50 g of dextrin, and 25 g of gum arabic, and mix evenly. It is advisable to pass through a 16-mesh sieve. After adding 2.5g of magnesium stearate to the prepared granules, use a rotary tablet press to process them into oral tablets with round shapes and plant flavonoids. The weight of each tablet is controlled...
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