Chinese medicine compound for gout prevention

A composition and technology for gout, which can be used in drug combinations, bone diseases, pharmaceutical formulations, etc., and can solve problems such as unpublished efficacy

Inactive Publication Date: 2010-06-30
BEIJING TIANKE RENXIANG MEDICAL SCI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above two traditional Chinese medicines are formulated according to the theory of dialectical treatment of traditional Chinese medicine. Although they have certain curative effects, the specific curative effects have not been announced, and there are great limitations in clinical application.

Method used

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  • Chinese medicine compound for gout prevention
  • Chinese medicine compound for gout prevention

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Use the following combination of Chinese medicine:

[0044] Codonopsis 30g, Guizhi 40g, Chuanxiong 20g, Myrrh 75g

[0045] Atractylodes 70g Poria 90g Gastrodia elata 45g Angelica dahurica 65g

[0046] Yanhu Suo 45g Woody Fragrance 25g

[0047] Its preparation method is:

[0048] (1) Poria cocos 90g, Gastrodia elata 45g, pulverize respectively, sieve, get fine powder, set aside;

[0049] (2) Rhizoma Chuanxiong 20g, Atractylodes atractylodes 70g, and woody root 25g, mix, grind into coarse powder, extract volatile oil by steam distillation (filter the distilled aqueous solution, and use the filtrate for later use), the obtained volatile oil is clathrated with β-cyclodextrin, and freeze-dried , to obtain the clathrate of volatile oil, for subsequent use;

[0050] (3) The rest of Codonopsis pilosula, Guizhi and other five flavors are mixed, soaked in 70% ethanol for 3 hours, heated and refluxed for 3 times, 1 hour each time, filtered, and the filtrate is decompressed to ...

Embodiment 2

[0053] Use the following combination of Chinese medicine:

[0054] Codonopsis 35g, Guizhi 60g, Chuanxiong 30g, Myrrh 90g

[0055] Cangzhu 100g Poria cocos 115g Gastrodia elata 60g Angelica dahurica 90g

[0056] Yanhu Suo 60g Woody Fragrance 35g

[0057] Its preparation method is:

[0058] (1) Poria cocos 115g, Gastrodia elata 60g, pulverize respectively, sieve, get fine powder, set aside;

[0059] (2) Rhizoma Chuanxiong 30g, Atractylodes atractylodes 100g, woody 35g, mix, grind into coarse powder, extract the volatile oil by steam distillation (filter the distilled aqueous solution, and use the filtrate for later use), the obtained volatile oil is clathrated with β-cyclodextrin, and freeze-dried , to obtain the clathrate of volatile oil, for later use;

[0060] (3) The rest of Codonopsis pilosula, Guizhi and other five flavors are mixed, soaked in 60% ethanol for 5 hours, heated and refluxed for 3 times, 2 hours for the first time, 1 hour for the second and third times, comb...

Embodiment 3

[0063] Use the following combination of Chinese medicine:

[0064] Codonopsis 15g, Guizhi 25g, Chuanxiong 12g, Myrrh 50g

[0065] Cangzhu 50g Poria cocos 60g Gastrodia elata 20g Angelica dahurica 40g

[0066] Yanhu Suo 25g Woody Fragrance 15g

[0067] Its preparation method is:

[0068] (1) Poria cocos 60g, Gastrodia elata 20g, pulverize respectively, sieve, get fine powder, set aside;

[0069] (2) Rhizoma Chuanxiong 12g, Atractylodes atractylodis 50g, Woody Fragrant 15g, mix, pulverize into coarse powder, extract volatile oil by steam distillation (filter the distilled aqueous solution, the filtrate is for later use), the obtained volatile oil is clathrated with β-cyclodextrin, freeze-dried , to obtain the clathrate of volatile oil, for later use;

[0070] (3) The rest of Codonopsis pilosula, cassia twig and other five flavors are mixed, soaked in 80% ethanol for 2 hours, heated and refluxed twice, 1 hour each time, filtered, and the filtrate is decompressed to recover et...

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Abstract

The invention discloses a Chinese medicine compound for gout prevention, which belongs to the field of Chinese medicine pharmacy. The Chinese medicine compound is a capsule processed through a conventional extraction method with a total of ten Chinese medicines, i.e. codonopsis, cassia twigs, szechwan lovage rhizome, myrrh, atractylodes, poria, tianma, angelica, corydalis and saussurea as the raw material. The Chinese medicine compound has the effect of clearing heat and removing dampness through diuresis, and removing obstruction in channels to relieve pain, and is used to prevent acute gout. We take tests through a hot plate method and an acetic acid writhing method to observe the abirritation of the Chinese medicine compound., and the results show that the Chinese medicine compound has significant abirritation, and is characterized by significant therapic effect, no side effect and the like in gout prevention.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for preventing and treating gout, and belongs to the field of traditional Chinese medicine pharmacy. Background technique [0002] According to modern medical theory, gout is caused by the disorder of purine metabolism in the human body, which causes excessive uric acid in the blood, and forms urate crystals and stones in joints, soft tissues, kidneys, etc., causing lesions in these parts. The existing medicines on the market are only limited to clearing up uric acid in the body and reducing the laboratory value of uric acid, so the relapse cannot be controlled. Western medicines for the clinical treatment of gout mainly include allopurinol, colchicine, benzbromarone, probenecid, etc., which can accelerate the excretion of uric acid and inhibit the production of uric acid to a certain extent, but long-term use can seriously d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8988A61P19/06
Inventor 伍荣林
Owner BEIJING TIANKE RENXIANG MEDICAL SCI TECH
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