Interface unit containing capillary electrophoresis of hollow-fiber membrane and chemoluminescence combination

A technology of capillary electrophoresis and chemiluminescence, which is applied in the fields of chemiluminescence/bioluminescence, measurement devices, and analysis by making materials react chemically, and can solve the problem of limiting the application range of chemiluminescence capillary electrophoresis detectors and the mixing of luminescent reagents and analytes Insufficient uniformity and stability, capillary electrophoresis cut-off and other problems, to achieve separation analysis, improve column efficiency and detection sensitivity, and eliminate dead volume
CN101782504BInactive Publication Date: 2013-07-10EAST CHINA UNIV OF SCI & TECH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
EAST CHINA UNIV OF SCI & TECH
Publication Date
2013-07-10
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to an interface unit containing capillary electrophoresis of a hollow-fiber membrane and chemoluminescence combination, which at least comprises a hollow-fiber membrane. The hollow-fiber membrane is arranged between an injection port of a capillary and a detection window, both ends of the hollow-fiber membrane are respectively inserted into a Teflon tube, and the edges for connecting the Teflon tube with the hollow-fiber membrane are bonded and sealed by epoxide resin; chemiluminescence reagent is mixed with a sample through the hollow-fiber membrane, the chemiluminescence reaction is carried out, and a chemiluminescence detector is used for further detection. The interface unit has the advantages of high column efficiency and detection sensitivity, simple structure,convenient operation, easy control and wide application range.
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Description

【Technical field】

[0001] The invention relates to the technical field of capillary electrophoresis, in particular to an interface device for combining capillary electrophoresis and chemiluminescence with a hollow fiber membrane. 【Background technique】

[0002] Capillary electrophoresis (CE), a new separation technique developed in the 1980s, has become one of the most active research directions in analytical chemistry. While capillary electrophoresis has the advantages of high efficiency, rapidity, less sample volume and less reagent consumption, it is also restricted by the difficulty of micro sample detection. Solving the problem of capillary electrophoresis micro sample detection is one of the key technologies for the further development of this method . Combined with the highly sensitive and convenient chemiluminescence detection technology, the application range of capillary electrophoresis can be broadened to a certain extent. The combination of capillary electrophor...

Claims

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