Salvianic acid A pharmaceutical composition and preparation method thereof

Abstract

The invention relates to a salvianic acid A pharmaceutical composition and a preparation method thereof. Salvianic acid A can be dissolved in water, but the preparation of the salvianic acid A has poor stability, is easy for oxidization, is sensitive to light and heat, and causes content reduction and impurity increase, and the guarantee on the stability is a technical problem. The salvianic acid A pharmaceutical composition comprises the salvianic acid A, a pharmacological allowable pH adjusting substance, a stabilizing agent and an excipient. The salvianic acid A in the salvianic acid A pharmaceutical composition has the concentration of 0.5-2,000mg. The weight part of the pH adjusting substance is the adding dosage when a pH value is adjusted to 2.5-7.5, and the stabilizing agent in the salvianic acid A pharmaceutical composition has the concentration of 1mg-0.5g. The salvianic acid A pharmaceutical composition is used as an injection with the effects of protecting the cardiac muscle, promoting blood circulation, removing blood stasis, resisting bacteria, eliminating inflammation, strengthening body immunity, resisting atherosclerosis, reducing blood fat, resisting platelet aggregation, resisting thrombosis, expanding the coronary artery, treating liver injury, resisting cerebral ischemia injury, resisting tumors, and the like and a therapeutical effect on pulmonary heart disease, psoriasis, altitude disease, and the like.

Description

Technical field: The present invention relates to a kind of medicine that has the functions of protecting myocardium, promoting blood circulation and removing blood stasis, antibacterial and anti-inflammation, enhancing body immunity, resisting atherosclerosis, lowering blood fat, resisting platelet aggregation, resisting thrombosis, dilating coronary artery, treating liver injury and resisting cerebral ischemia. Injury, anti-tumor, etc., and an injection that has therapeutic effects on pulmonary heart disease, psoriasis, altitude sickness, etc., specifically relates to Danshensu powder injection and its preparation method. Background technique: Salvia miltiorrhiza is a traditional Chinese medicinal material with a long history and a wide range of applications in our country. At present, the injections involving danshen are only available in the market. Injections of active monomers in Danshen for clinical use. Danshensu is a water-soluble substance extracted from the dry r...

AI Technical Summary

Problems solved by technology

Danshensu can be dissolved in water, but its preparation has poor stability, is easily oxidized, and is sensitive to light and heat, resulting in a decrease in content and an increase in impurities. The guarantee of its stability is a technical difficulty

Images