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Method for preparing concentrated Yinhuang oral liquid

A Yinhuang oral liquid and concentrated technology, which is applied in the field of medicine, can solve the problems of low content of active ingredients, inconvenient carrying, high production cost, etc., and achieve the goal of increasing the content of active ingredients, saving raw materials and packaging materials, and being convenient to take and carry Effect

Active Publication Date: 2011-08-03
河南百年康鑫药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

It is widely used in patients with symptoms such as dry throat, sore throat, swollen laryngeal nucleus, thirst, fever, acute and chronic tonsillitis, acute and chronic pharyngitis, and upper respiratory tract infection caused by exogenous wind-heat and excessive heat in the lung and stomach. The production process is limited by the level of technology in the early years. It is just a simple water extraction and alcohol precipitation refining process. It has many impurities, low extraction utilization rate, low content of active ingredients, and poor taking effect. It is especially unfavorable for children and patients who have difficulty taking medicine. Convenience, difficult to improve the curative effect, at the same time, the consumption of raw materials and packaging materials is large, the production cost is high, and there are serious disadvantages in the production process

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  • Method for preparing concentrated Yinhuang oral liquid

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preparation example Construction

[0007] The preparation method of the present invention is: by weight percent: 5-15% of honeysuckle extract, 85-95% of scutellaria baicalensis extract, 100% of the total amount are used as raw materials of medicinal materials, and are prepared according to the following steps:

[0008] (1), get honeysuckle, add mass concentration and be 15% ethanol reflux extraction twice, add 10 times of honeysuckle weight ethanol reflux extraction for 1 hour for the first time, add 8 times of honeysuckle weight ethanol reflux extraction for the second time 1 hours, combined the two extracts, concentrated under reduced pressure to 60 ° C to measure the relative density (specific gravity, the same below) as the clear paste of 1.15 to 1.18, added ethanol to make the alcohol content reach 65%, let it stand for 24 hours, and took the supernatant , concentrated under reduced pressure to 60°C to measure a paste with a relative density of 1.20-1.24, add water to 2-2.5 times the weight of honeysuckle, ...

Embodiment 1

[0013] In terms of weight percentage: 5% of honeysuckle extract, 95% of scutellaria baicalensis extract, 100% of the total amount are used as medicinal raw materials, and are prepared according to the following steps:

[0014] (1), get honeysuckle, add mass concentration and be 15% ethanol reflux extraction twice, add 10 times of honeysuckle weight ethanol reflux extraction for 1 hour for the first time, add 8 times of honeysuckle weight ethanol reflux extraction for the second time 1 hours, combined the two extracts, concentrated under reduced pressure to 60°C to measure the clear paste with a relative density of 1.15, added ethanol to make the alcohol content reach 65%, left it for 24 hours, took the supernatant, concentrated under reduced pressure to 60°C and measured Add water to the paste with a relative density of 1.20 to twice the weight of honeysuckle, seal it, refrigerate for more than 24 hours, take the supernatant, and obtain the honeysuckle extract;

[0015] (2) Ta...

Embodiment 2

[0019] In terms of weight percentage: 15% of honeysuckle extract, 85% of scutellaria baicalensis extract, and 100% of the total amount are used as medicinal raw materials, and are prepared according to the following steps:

[0020] (1), get honeysuckle, add mass concentration and be 15% ethanol reflux extraction twice, add 10 times of honeysuckle weight ethanol reflux extraction for 1 hour for the first time, add 8 times of honeysuckle weight ethanol reflux extraction for the second time 1 hours, combined two extracts, concentrated under reduced pressure to 60°C to measure the clear paste with a relative density of 1.18, added ethanol to make the alcohol content reach 65%, left it for 24 hours, took the supernatant, concentrated under reduced pressure to 60°C and measured Add water to the ointment with a relative density of 1.24 to 2.5 times the weight of honeysuckle, airtight, refrigerate for more than 24 hours, and take the supernatant to obtain the honeysuckle extract;

[0...

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Abstract

The invention relates to a method for preparing concentrated Yinhuang oral liquid, effectively increases the concentration of oral liquid and the content of active ingredients, and provides the method for preparing concentrated Yinhuang oral liquid which is convenient to carry, easy to take and high in efficacy. The invention adopts a technical scheme that 5 to 15 weight percent of honeysuckle flower extract and 85 to 95 weight percent of baikal skullcap root extract are taken as raw medicinal materials; and the method comprises the steps of preparing the honeysuckle flower extract and the baikal skullcap root extract first, adding water to dissolve the baikal skullcap root extract, using sodium hydroxide solution to regulate pH, filtering the obtained product, combining filtrate with thehoneysuckle flower extract, using the sodium hydroxide solution to regulate pH, boiling and filtering the obtained product, adding simple syrup and water, mixing well, using the sodium hydroxide solution to regulate pH again, adding water to full dose, stirring uniformly, separating the obtained product through a high-speed centrifuge to obtain clear liquid, subjecting the clear liquid to ultra-filtration to obtain the filtrate, pouring, sealing and sterilizing the obtained product. The method has the advantages of reducing the amount of oral administration to half of the original taking amount, allowing the oral liquid to be easy to take, improving efficacy up to over 93 percent, reducing production cost and ensuring more taking-carrying convenience.

Description

1. Technical field [0001] The invention relates to the field of medicine, in particular to a preparation method of concentrated Yinhuang oral liquid. 2. Background technology [0002] Yinhuang oral liquid is a traditional Chinese medicine preparation, which has the effects of clearing away heat and dispelling wind, relieving sore throat and detoxification. It is widely used in patients with symptoms such as dry throat, sore throat, swollen laryngeal nucleus, thirst, fever, acute and chronic tonsillitis, acute and chronic pharyngitis, and upper respiratory tract infection caused by exogenous wind-heat and excessive heat in the lung and stomach. The production process is limited by the level of technology in the early years. It is just a simple water extraction and alcohol precipitation refining process. It has many impurities, low extraction utilization rate, low content of active ingredients, and poor taking effect. It is especially unfavorable for children and patients who ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61P9/08A61K36/539A61P11/00A61P11/04
Inventor 郭鑫慧蔡俊安王粉王艳丽
Owner 河南百年康鑫药业有限公司
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