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Medicament for treating liver-kidney yin deficiency type anovulatory dysfunctional uterine bleeding, and preparation method and application thereof

A yin-deficiency type, anovulatory technology, applied in the field of medicine, can solve the problems of inability to stop bleeding, multiple side effects, and easy recurrence of anovulatory DUB, and achieves regulation of hormone levels, good therapeutic effect, shortening of bleeding time and coagulation. effect of time

Inactive Publication Date: 2010-10-13
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although these methods can stop bleeding quickly, they cannot rely on it to stop bleeding, and they cannot adjust the menstrual cycle to prevent relapse.
It can be seen that Western medicine treatment of anovulatory DUB is prone to relapse and has more side effects

Method used

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  • Medicament for treating liver-kidney yin deficiency type anovulatory dysfunctional uterine bleeding, and preparation method and application thereof
  • Medicament for treating liver-kidney yin deficiency type anovulatory dysfunctional uterine bleeding, and preparation method and application thereof
  • Medicament for treating liver-kidney yin deficiency type anovulatory dysfunctional uterine bleeding, and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] The traditional Chinese medicine for treating liver and kidney yin deficiency type anovulatory DUB is made from the following raw materials in proportion by weight:

[0028] 190 parts of white peony (cooked) 270 parts of rehmannia, 190 parts of black lotus

[0029] Ligustrum lucidum 190 parts Dipsacus 190 parts Ejiao 30 parts

[0030] Panax notoginseng 190 parts Astragalus 430 parts Digupi 190 parts

[0031] Sea Cuttlefish 270 servings

Embodiment 2

[0033] The traditional Chinese medicine for treating liver and kidney yin deficiency type anovulatory DUB is made from the following raw materials in proportion by weight:

[0034] 290 parts of white peony (cooked) 370 parts of rehmannia, 290 parts of black lotus

[0035] Ligustrum lucidum 290 parts Dipsacus 290 parts Ejiao 130 parts

[0036] Panax notoginseng 290 parts Astragalus 530 parts Digupi 290 parts

[0037] Sea Cuttlefish 370 servings

Embodiment 3

[0039] The traditional Chinese medicine for treating liver and kidney yin deficiency type anovulatory DUB is made from the following raw materials in proportion by weight:

[0040] White peony root 238.1g (cooked) Rehmannia glutinosa 317.5g Black lotus 238.1g

[0041] Ligustrum lucidum 238.1g Dipsacus 238.1g Donkey-hide gelatin 79.4g

[0042] Sanqi 238.1g Astragalus 476.2g Digupi 238.1g

[0043] Sea Cuttlefish 317.5g

[0044] According to the formula quantity enumerated in embodiment 1~3, get Radix Paeoniae Alba, Eclipta, Ligustrum lucidum, Dipsacus, Radix Notoginseng, Radix Astragali six flavors, add the 70% ethanol of 18 times of the total weight of decoction pieces and divide three reflux extractions (three times) The dosage is respectively 40%, 30%, and 30% of the total amount), each time for 2 hours, the extracts are combined, filtered, and the filtrate is decompressed to recover ethanol, concentrated until it has no alcohol smell. Combine the above medicinal dregs with ...

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PUM

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Abstract

The invention relates to a medicament for treating liver-kidney yin deficiency type anovulatory dysfunctional uterine bleeding, and a preparation method and application thereof. The medicament is prepared from the following raw material medicaments in part by weight: 190 to 290 parts of white paeony root, 270 to 370 parts of rehmannia root, 190 to 290 parts of yerbadetajo herb, 190 to 290 parts of glossy privet fruit, 190 to 290 parts of himalayan teasel root, 30 to 130 parts of donkey-hide glue, 190 to 290 parts of radix pseudo-ginseng, 430 to 530 parts of astragalus, 190 to 290 parts of cortex lycii radicis and 270 to 370 parts of cuttlebone. The preparation method comprises the following steps of: according to the weight part, adding alcohol into the white paeony root, the yerbadetajo herb, the glossy privet fruit, the himalayan teasel root, the radix pseudo-ginseng and the astragalus for reflux and extraction, filtering, recovering the alcohol from the alcohol extract under reduced pressure, and concentrating the alcohol extract until the alcohol extract has no alcohol odor so as to obtain alcohol extract concentrated solution and decoction dregs for later use; and merging the decoction dregs with radix rehmanniae praeparata, the cortex lycii radicis and the cuttlebone, decocting the mixture by using water, filtering decoction, concentrating filter liquor under reduced pressure, adding the alcohol into the concentrated filter liquor, uniformly stirring, standing, filtering, recovering the alcohol from the filter liquor to obtain concentrated solution of water extraction and alcohol precipitation, merging the concentrated solution of water extraction and alcohol precipitation with the alcohol extract concentrated solution, adding the molten donkey-hide glue into the mixture, concentrating and performing vacuum drying to prepare dry extract powder.

Description

1. Technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a medicine for treating liver and kidney yin deficiency type anovulatory DUB and a preparation method thereof. 2. Background technology [0002] Dysfunctional uterine bleeding (DUB), referred to as dysfunctional uterine bleeding, refers to abnormal uterine bleeding caused by abnormal neuroendocrine mechanisms regulating reproduction. DUB can be divided into two categories: anovulatory and ovulatory. DUB is a common disease in gynecology, and its incidence rate accounts for about 10% of outpatient gynecological diseases. The anovulatory type is the most common, accounting for about 80-90%, mainly occurs in puberty and premenopause, and a few occur in childbearing age; the number of ovulatory DUB is relatively small. All anovulatory dysfunctional uterine bleeding due to different ages and different reasons belongs to anovulatory dysfunctional uterine bleeding. ...

Claims

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Application Information

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IPC IPC(8): A61K36/815A61P15/00A61P7/04A61K35/36A61K35/56A61K35/618
Inventor 毛春芹陈霞谈瑄忠陆兔林李林许惠琴李莉李争艳
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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