Composition for alleviation of alcohol induced hangover comprising hovenia dulcis thunberg contained ssangwhatang

A composition, the technology of Fructus Aurantii, applied in the directions of drug combination, application, food science, etc., can solve the problem of no Shuanghe soup, etc.

Active Publication Date: 2010-11-03
KOREA INST OF ORIENTAL MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no literature on how to ferment Shuanghetang in the known art

Method used

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  • Composition for alleviation of alcohol induced hangover comprising hovenia dulcis thunberg contained ssangwhatang
  • Composition for alleviation of alcohol induced hangover comprising hovenia dulcis thunberg contained ssangwhatang
  • Composition for alleviation of alcohol induced hangover comprising hovenia dulcis thunberg contained ssangwhatang

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] prepare flavored Shuanghe soup

[0025] Hovenia dulcis (502g), white peony root (468g), rehmannia glutinosa (187g), astragalus (187g), angelica (187g), chuanxiong (187g), cinnamon (140g), licorice (140g), dried ginger (74g) Mixed with jujube (100g) and extracted with hot water to obtain flavored Shuanghe soup containing Hovenia dulcis. The stock solution of Shuanghetang (10L) was added to a glass bottle (Pylex 19L), and the pH was adjusted to 7.0 with NaOH (1M). The resulting mixture was autoclaved at 121° C. for 15 minutes at 1.5 atm.

Embodiment 2

[0026] prepare the Shuanghe Tang fermented by Lactobacillus

[0027] Distribution of Lactobacillus

[0028] Seven strains of the genus Lactobacillus were provided by the Food Microorganism Gene Bank (KFRI) of the Korea Food Research Institute, and one strain of the genus Lactobacillus was provided by the Korean Collection of Type Cultures (KCTC). They were used in this experiment (see Table 1).

[0029]Table 1: Lactobacillus strains used in fermentation

[0030] Table 1

[0031] strain number.

strain

KFRI 128

Lactobacillus acidophilus

164

Lactobacillus fermentum

[0032] strain number.

strain

345

Lactobacillus bulgaricus

442

Lactobacillus delbrueckii subsp.

658

Lactobacillus gasseri

692

Lactobacillus casei

693

Lactobacillus casei

KCTC 5033

Lactobacillus rhamnosus

[0033] Seed cell culture

[0034] The 8 bacterial strains provided in we...

experiment Embodiment 1

[0039] Confirmation of Relief of Alcohol-Induced Hangover

[0040] Eight-week-old male rats obtained from Orientbio Inc. (Korea) were isolated and purified for two weeks in the animal laboratory of the Korean Academy of Korean Medicine. Healthy rats were selected from these rats and used in this experiment.

[0041] Grouping and animal identification

[0042] Rats were grouped as follows. The body weight of the rats judged to be healthy during the purification was measured and divided every 5 g, and 108 rats close to the average weight were selected. The 108 rats were allocated by random method with random number and graded weight, so that each group contained 6 rats of the same body weight. Rats were identified by the method of pigmentation of the hair and the display of individual identification cards.

[0043] Analysis of changes in serum-alcohol concentration

[0044] Experiment A was conducted to find out the pre-hangover relief effect. 60% ethanol 10 ml / kg was o...

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PUM

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Abstract

A composition for alleviation of alcohol induced hangover comprises Ssangwhatang including Hoveniae Semen or lactobacillus fermented Ssangwhatang as an effective ingredient. Specifically, the composition comprises Ssangwhatang including Hoveniae Semen extracts or lactobacillus fermented Ssangwhatang prepared by inoculating, culturing and fermenting or lactobacillus. The composition is useful in alleviation of alcohol induced hangover and reducing blood-alcohol concentration during alcohol intake when taken as a health food.

Description

field of invention [0001] The invention relates to a composition for alleviating alcohol-induced hangover, which uses flavored Shuanghe decoction containing Hovenia dulcis Thunberg or Shuanghe decoction fermented by lactobacillus as an active ingredient. Background technique [0002] Ssangwhatang (Ssangwhatang), also known as Ssangwhasan, is prescribed in the item "Weakness and Fatigue" of the "Various Diseases" chapter of Donguibogam as a prescription for relieving fatigue. Shuanghe Decoction is obtained by adding "Siwu Decoction" (Samultang, including rehmannia glutinosa, white peony root, chuanxiong and angelica) to "Lizhong Decoction" (Yijungtang, including ginseng, Atractylodes macrocephala, dried ginger and licorice). Shuang He Tang can be used for people who feel tired, have blood disorders, are weak after a severe illness, lack energy, and sweat a lot. [0003] Shuang He Tang includes herbs such as White Peony (Paeonia japonica), Rehmannia glutinosa, Astragalus memb...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/65
CPCA61K36/65A61K36/484A61K36/232A61K36/54A61K36/9068A61K36/481A61K36/725A61K36/72A61P1/08A61P39/00A61K2300/00A23V2200/334A61K36/804A61K2236/19C12P1/04
Inventor 马珍烈
Owner KOREA INST OF ORIENTAL MEDICINE
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