Composition for alleviation of alcohol induced hangover comprising hovenia dulcis thunberg contained ssangwhatang
A composition, the technology of Fructus Aurantii, applied in the directions of drug combination, application, food science, etc., can solve the problem of no Shuanghe soup, etc.
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Embodiment 1
[0024] prepare flavored Shuanghe soup
[0025] Hovenia dulcis (502g), white peony root (468g), rehmannia glutinosa (187g), astragalus (187g), angelica (187g), chuanxiong (187g), cinnamon (140g), licorice (140g), dried ginger (74g) Mixed with jujube (100g) and extracted with hot water to obtain flavored Shuanghe soup containing Hovenia dulcis. The stock solution of Shuanghetang (10L) was added to a glass bottle (Pylex 19L), and the pH was adjusted to 7.0 with NaOH (1M). The resulting mixture was autoclaved at 121° C. for 15 minutes at 1.5 atm.
Embodiment 2
[0026] prepare the Shuanghe Tang fermented by Lactobacillus
[0027] Distribution of Lactobacillus
[0028] Seven strains of the genus Lactobacillus were provided by the Food Microorganism Gene Bank (KFRI) of the Korea Food Research Institute, and one strain of the genus Lactobacillus was provided by the Korean Collection of Type Cultures (KCTC). They were used in this experiment (see Table 1).
[0029]Table 1: Lactobacillus strains used in fermentation
[0030] Table 1
[0031] strain number.
strain
KFRI 128
164
[0032] strain number.
strain
345
Lactobacillus bulgaricus
442
Lactobacillus delbrueckii subsp.
658
692
693
KCTC 5033
[0033] Seed cell culture
[0034] The 8 bacterial strains provided in we...
experiment Embodiment 1
[0039] Confirmation of Relief of Alcohol-Induced Hangover
[0040] Eight-week-old male rats obtained from Orientbio Inc. (Korea) were isolated and purified for two weeks in the animal laboratory of the Korean Academy of Korean Medicine. Healthy rats were selected from these rats and used in this experiment.
[0041] Grouping and animal identification
[0042] Rats were grouped as follows. The body weight of the rats judged to be healthy during the purification was measured and divided every 5 g, and 108 rats close to the average weight were selected. The 108 rats were allocated by random method with random number and graded weight, so that each group contained 6 rats of the same body weight. Rats were identified by the method of pigmentation of the hair and the display of individual identification cards.
[0043] Analysis of changes in serum-alcohol concentration
[0044] Experiment A was conducted to find out the pre-hangover relief effect. 60% ethanol 10 ml / kg was o...
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