Mouth rinse for removing halitosis and preparation method thereof

A technology of mouthwash and deionized water, which is applied in oral care, pharmaceutical formulations, cosmetic preparations, etc., can solve the problems of limited applicability, single active ingredient of mouthwash, and insignificant curative effect, and achieve wide applicability, Good taste and good drug resistance

Active Publication Date: 2010-12-01
GUANGZHOU INST OF BIOMEDICINE & HEALTH CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the mouthwash disclosed in this patent has a single active ingredient, is not widely applicable, and has no significant curative effect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] A mouthwash for removing bad breath, comprising the following components:

[0037] Ornidazole and Tinidazole 0.5g

[0038] Chinese Herbal Medicine (Lobelia, Galla, Chrysanthemum Chrysanthemi, and Bamboo Leaf) Extract 1.0g

[0039] Menthol 0.2g

[0040] Glycerin (glycerol) 20mL

[0041] Surfactant (sodium carboxymethylcellulose) 1.0g

[0042] Add deionized water to 1000mL

[0043] The deodorant mouthwash of embodiment 1 is prepared through the following steps:

[0044] (1) According to the conventional method, take Chinese herbal medicines (the approximate weight ratio of Lobelia, Galla gall, Chrysanthemum chrysanthemum and Bamboo leaves is 15:20:30:10.) After fully soaking with hot water and ethanol in turn, the obtained liquid is filtered, and the filtrates are combined Concentrate under reduced pressure to obtain the Chinese herbal medicine extract, take the Chinese herbal medicine extract and dissolve it in a mixed solution of deionized water, glycerin and surfa...

Embodiment 2

[0050] A mouthwash for removing bad breath, comprising the following components:

[0051] Metronidazole 5.0g

[0052] Chinese Herbal Medicine (Lobelia, Galla, Chrysanthemum Chrysanthemi and Bamboo Leaf) Extract 2.0g

[0053] Menthol 0.3g

[0054] Glycerin (glycerol) 18mL

[0055] Surfactant (sodium carboxymethylcellulose) 3.0g

[0056] Add deionized water to 1000mL

[0057] The approximate weight ratio of lobelia, Galla chinensis, Hangbai chrysanthemum and light bamboo leaves is 15:20:30:10.

[0058] The deodorant mouthwash of the present embodiment was prepared according to the preparation method of Example 1. Use the mouthwash of this embodiment to gargle for 30 seconds, and the effect of removing oral odor is better.

Embodiment 3

[0060] A mouthwash for removing bad breath, comprising the following components:

[0061] Tinidazole 0.05g

[0062] Chinese herbal medicine (lobelia, Galla gall, Chrysanthemum chrysanthemum, Bamboo leaves, Honeysuckle and Smilax smilax) extract 2.0g

[0063] Menthol 0.1g

[0064]Glycerin 25mL

[0065] Surfactant (sodium lauryl sarcosinate) 1.0g

[0066] Flavor 1.0g

[0067] Add deionized water to 1000mL

[0068] The approximate weight ratio of lobelia, Galla gall, Chrysanthemum chrysanthemum, Bamboo leaves, Honeysuckle and Smilax smilax is 15:20:30:10:30:20.

[0069] Prepare the deodorant mouthwash of this embodiment according to the preparation method of Example 1 (add essence in step 4). Use the mouthwash of this embodiment to gargle for 30 seconds, and the effect of removing oral odor is better.

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PUM

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Abstract

The method discloses a mouth rinse for removing halitosis and a preparation method thereof. The mouth rinse for removing halitosis comprises nidazole medicines, Chinese herbal medicine extracts, menthol, glycerin, a surface active agent and deionized water. In the invention, the mouth rinse for removing halitosis takes the nidazole medicines as a main therapeutic ingredient, and enhances therapeutic effect by adding the Chinese herbal medicine extracts for health care. Compared with the mouth rinse with a single active ingredient, the mouth rinse of the invention can be applicable to more indications, has more obvious therapeutic effect on removing oral abnormal odor, can effectively improve oral inflammation without destroying normal oral floras, and has the advantages of short use time, good drug resistance, convenient use, good mouth feel and easy acceptance of patients.

Description

technical field [0001] The invention relates to a halitosis-removing mouthwash and a preparation method thereof. Background technique [0002] Bad breath is caused by anaerobic bacteria, or the fermentation of food left in the mouth to produce sulfides. Among the patients with oral infection, the infection rate of anaerobic bacteria accounted for 96% of odontogenic infections, and 73.7% of non-odontogenic infections. It can be seen that the proportion of anaerobic bacteria in oral infections is large. In order to make the patient's disease treatment achieve better curative effect, the patient is required to cooperate with the use of mouthwash after clinical treatment. Therefore, choosing a suitable anti-anaerobic mouthwash has become an important link in the treatment of oral anaerobic infectious diseases. [0003] There are two categories of mouthwashes approved by the Food and Drug Administration (FDA): those containing essential oils and those containing chlorhexidine. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/98A61K8/97A61K8/49A61Q11/00A61K8/9789A61K8/9794
Inventor 胡文辉曾少高
Owner GUANGZHOU INST OF BIOMEDICINE & HEALTH CHINESE ACAD OF SCI
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