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Preparation method of medicine for preventing and treating acute upper respiratory tract infection

An upper respiratory tract and drug technology, applied in the directions of drug combination, pharmaceutical formula, respiratory system diseases, etc., can solve the problem of no ideal prevention method for upper respiratory tract infection, reduce the volume of drugs used, improve the antibacterial spectrum and antibacterial strength, and is convenient carry effect

Inactive Publication Date: 2011-04-06
YUNNAN UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, modern medicine has no ideal preventive method for upper respiratory tract infection so far.

Method used

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  • Preparation method of medicine for preventing and treating acute upper respiratory tract infection

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] 1.1. Prescription: Forsythia 240g, Honeysuckle 240g, Mint 120g

[0020] 160g burdock seed 240g platycodon root 240g dried

[0021] Banlangen 240g Fangfeng 240g Guanzhong 240g

[0022] 120g of licorice made into 1000ml;

[0023] 1.2. Preparation of ZTC1+1III flocculant and flocculant assistant:

[0024] Preparation of ZTC1+1III flocculant: Weigh 10g ZTC1+1III, first stir it into a paste with a small amount of distilled water, then add distilled water to 1000mL, swell for 24 hours, stir well, filter with double gauze to obtain a mass concentration of 1% flocculant;

[0025] Preparation of ZTC1+1III flocculant aid: Weigh 20g ZTC1+1III, dissolve it with a small amount of 1% acetic acid solution and stir it into a paste, then add 1% acetic acid to 2000mL, swell for 24 hours, stir well, Double-layer gauze filtration to obtain a flocculant with a mass concentration of 1%;

[0026] 1.3. Preparation method:

[0027] A. Add 8 times the amount...

Embodiment 2

[0032] 2.1. Prescription: Forsythia 240g, Honeysuckle 240g, Mint 120g

[0033] 160g burdock seed 240g platycodon root 240g dried

[0034] Banlangen 240g Fangfeng 240g Guanzhong 240g

[0035] Licorice 120g made into 1000ml

[0036] 2.2. Preparation method:

[0037] A. Add 10 times the amount of water to 120g mint, soak for 1h, extract for 3h, filter to obtain volatile matter, extract and filter residue respectively;

[0038] B. Mix the remaining 9 medicinal materials, add 10 times the amount of water, soak for 1 hour, add the filter residue from step A, reflux extraction for 3 times, each time for 2 hours, filter, and combine the filtrates;

[0039] C. Combine the extract of step A and the filtrate of step B, concentrate at normal pressure into a concentrated solution with a relative density of 0.4 at 50°C, put the concentrated solution into a magnetic stirrer and heat at 80°C, Add 3 grams of water-soluble chitosan, stir at a speed of 200r / m...

Embodiment 3

[0042] 3.1 [Prescription] Forsythia 240g, honeysuckle 240g, mint 120g

[0043] 160g burdock seed 240g platycodon root 240g dried

[0044] Banlangen 240g Fangfeng 240g Guanzhong 240g

[0045] Licorice 120g made into 1000ml

[0046] 3.2 [Preparation method]:

[0047] A. Add 12 times the amount of water to 120g mint, soak for 0.5h, extract for 4h, filter to obtain volatile matter, extract and filter residue respectively;

[0048] B. Mix the remaining 9 medicinal materials, add 12 times the amount of water, soak for 0.5h, add the filter residue from step A, reflux extraction twice, each time for 3h, filter, and combine the filtrates;

[0049] C, the extract of step A is combined with the filtrate of step B, and concentrated at normal pressure into a concentrated solution with a relative density of 1.2 at 50°C, and ethanol with a mass concentration of 95% is added to the concentrated solution until the alcohol content is 80% mass ratio, stirred ...

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Abstract

The invention provides a preparation method of a medicine for preventing and treating acute upper respiratory tract infection. The medicine is prepared from the following raw materials in percentage by mass: 5 to 25 percent of fructus forsythiae, 8 to 25 percent of honeysuckle flower, 3 to 12 percent of field mint, 8 to 25 percent of great burdock fruit, 10 to 20 percent of balloon flower root, 6 to 15 percent of belamcandae root, 8 to 20 percent of isatis root, 8 to 20 percent of ledebouriella root, 8 to 20 percent of dryopteris root and 3 to 12 percent of licorice root. The raw medicines are extracted, concentrated, flocculated, clarified and then concentrated, and a preparation for preventing and treating acute upper respiratory tract infection is obtained under the condition of preserving the effect of raw medicines to a full extent. Proved by results of bacteriostatic tests on main pathogenic bacteria and pharmacology and toxicology tests on pain alleviation, inflammation resistance, and the like, the technology has the advantages of effectively enriching main active ingredients in raw medicines, reducing the losses of main active ingredients and improving antibacterial spectrum and bacteriostatic strength. The medicine effect, the safety and the reliability are better than those of a preparation made from the same raw materials with a traditional method. Meanwhile, preparation clarity can be improved, medicine occupation volume can be reduced, and the medicine is convenient to carry and convenient for children to take.

Description

[0001] The invention relates to a preparation method of a medicine, in particular to a preparation method of a medicine for preventing and treating acute upper respiratory tract infection, and belongs to the field of biotechnology. Background technique [0002] Acute upper respiratory tract infection is a general term for acute inflammation of the nasal cavity, pharynx or larynx, and is the most common infectious disease of the respiratory tract. About 70-80% of the disease is caused by viruses, mainly influenza virus A, B, C, parainfluenza virus, respiratory syncytial virus, adenovirus, rhinovirus, Echo virus, Coxsackie virus, measles virus, Rubella virus, etc., adults are mainly rhinovirus, while children are mainly parainfluenza virus and respiratory syncytial virus. All can fall ill throughout the year, frequently occurs in winter and spring, and is often prevalent when there is a sudden change in climate. Modern virology and clinical immunology believe that the pathogeni...

Claims

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Application Information

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IPC IPC(8): A61K36/88A61P11/02A61P11/04
Inventor 李安华
Owner YUNNAN UNIV OF TRADITIONAL CHINESE MEDICINE
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