Pharmaceutical composition for preventing and treating climacteric metancholia and other diseases
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A composition and drug technology, applied in the field of medicine, can solve problems such as large side effects
Inactive Publication Date: 2011-05-04
王新祥 +1
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At present, estrogen replacement therapy has a certain effect on the prevention and treatment of these diseases, but it cannot meet the clinical needs well due to the large side effects
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Embodiment 1
[0018] Yiqi Congmingtang Powder was prepared with reference to the preparation method of Yiqi Congcongming Pills issued by the Ministry of Traditional Chinese Medicine (Standard Book issued by the Ministry of Traditional Chinese Medicine Page Number: Z4-164 Standard Number: WS3-B-0820-91). That is: Codonopsis 100g, Astragalus 100g, Cimicifuga 60g, Pueraria 60g, Cortex Phellodendri (fried) 20g, Paeoniae Alba 20g, Vitex 30g, Licorice (burnt) 10g, the above eight flavors, crushed into fine powder, sieved, and mixed , that is, Yiqi Congming Decoction Powder. Take orally, 6-18g once, 1-3 times a day, for the prevention and treatment of menopausal syndrome, chronic vaginitis in the elderly, chronic urethritis or cystitis in the elderly, and chronic prostatic hypertrophy in the elderly.
Embodiment 2
[0020] Take each raw material: 60g ginseng, 120g astragalus, 60g cohosh, 120g kudzu root, 30g vitex, 20g cork, 60g white peony, 10g licorice, mix the above eight flavors, soak in 5-10 times the extraction solvent, and reflux Extract one or more times to obtain the extract. The extraction solvent can be 0-95% ethanol aqueous solution, preferably 30-95% ethanol, preferably 8 times the extraction solvent during reflux extraction, and reflux 3 times for 2 hours each time. The solvent is recovered under reduced pressure, dried and crushed into fine powder to obtain the powder of the concentrate or extract. The obtained concentrate or extract powder is mixed with common auxiliary materials for making capsules, and packed into capsules to make capsules. The oral dose is converted according to the concentration ratio of the raw material drug. The final concentration ratio of the raw material medicine is 10 times, and the raw material medicine is calculated as 6-18g each time, so the...
Embodiment 3
[0022] Take the raw materials: 60g ginseng, 100g astragalus, 60g cohosh, 100g kudzu root, 30g vitex, 20g cork, 60g white peony, 10g licorice, soak them in 5-10 times extraction solvent respectively, and reflux extraction for one to Many times, the extract was obtained. The extraction solvent can be 0-95% ethanol aqueous solution, preferably 30-95% ethanol, preferably 8 times the extraction solvent during reflux extraction, and reflux 3 times for 2 hours each time. The solvent is recovered under reduced pressure, the concentrates or extracts of each drug are dried, pulverized, mixed, added with commonly used excipients for tablets, and pressed into tablets to obtain tablets, which can also be made into different dosage forms such as pills, ointments, and mixtures according to conventional methods. After making tablets, the final concentration ratio of the raw material drug is 10 times, and the raw material drug is calculated as 6-18g each time, then the amount of the concentrat...
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Abstract
The invention provides a pharmaceutical composition for preventing and treating climacteric metancholia and other diseases, relating to the field of medical technology, and particularly providing a new application of a pharmaceutical composition which is called as Qi-replenishing sharp and bright decoction and is composed of ginseng or codonopsis pilosula, astragalus membranaceus, cimicifugae foetidae, root of kudzuvine, simpleleaf shrub chastetree fruit, radix paeoniae alba, cortex phellodendri and liquorice in the preparation of a drug or food for preventing and treating climacteric metancholia, senile chronic vaginitis, senile chronic urethritis or cystitis, and senile chronic prostate hypertrophy as a main raw material. In addition, the invention further relates to an application of a new pharmaceutical composition which is obtained according to the modification of prescription of the Qi-replenishing sharp and bright decoction or the prescription of the Qi-replenishing sharp and bright decoction in the preparation of a drug or food for preventing and treating the diseases above as a main raw material. The pharmaceutical composition for preventing and treating climacteric metancholia and other diseases provided by the invention has the advantages that the raw materials of the pharmaceutical composition can be mixed after crushing to powder independently or crushed to powder after mixing, the edible preparation can be prepared directly, the raw materials can be mixed after extracting independently or extracted after mixing, and the pharmaceutical composition is prepared into all the normally used pharmaceutical dosage forms such as pills, powders, capsules, tablets, medicinal granules, oral liquids and the like together with pharmaceutically acceptable accessories.
Description
technical field [0001] The invention relates to the technical field of medicine, and relates to a pharmaceutical composition called Yiqi Congming Decoction composed of ginseng or Codonopsis, Astragalus, Cimicifuga, Pueraria, Radix Paeoniae Alba, Phellodendron Phellodendri and Licorice as the main raw material, which is used for the preparation of prophylaxis And the new application of medicine or food for treating menopausal syndrome, senile chronic vaginitis, senile chronic urethritis or cystitis, senile chronic prostatic hypertrophy. At the same time, the present invention also relates to the addition and subtraction of Yiqi Congcong Decoction or the use of a new pharmaceutical composition formed under the guidance of the principle of Yiqi Congcong Decoction as the main raw material for the preparation of medicines or food for the prevention and treatment of the above diseases . Background technique [0002] Yiqi Congming Decoction has the functions of nourishing qi and p...
Claims
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Application Information
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