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Oral spray for inflammatory diseases of oral cavity and preparation method thereof

A technology for oral inflammation and oral spray, applied in the field of medicine, can solve the problems of reducing the quality of life, large side effects, affecting the work and life of patients, etc.

Active Publication Date: 2011-06-08
武汉耦合医学科技有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although oral inflammatory diseases are self-limiting to a certain extent, the pain or bleeding caused after the onset seriously affects the patient's work and life.
Pain or bleeding from the lesion often affects eating and speaking, leading to indigestion, mental anxiety, and greatly reducing the quality of life
However, the side effects of systemic application of analgesic or hemostatic drugs are relatively large, and they have no local anti-inflammatory and wound-healing effects. Therefore, the local comprehensive treatment of oral inflammatory diseases has become an urgent problem to be solved, and it is required to be easy to use. , rapid onset, and no side effects

Method used

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  • Oral spray for inflammatory diseases of oral cavity and preparation method thereof
  • Oral spray for inflammatory diseases of oral cavity and preparation method thereof
  • Oral spray for inflammatory diseases of oral cavity and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] One. preparation gross weight is the oral cavity spray of the oral cavity inflammatory disease of 1000g:

[0035] a), take by weighing 1g carboxymethyl chitosan, 5g propolis extract respectively, be dissolved in the preparation solution in 200g water for injection;

[0036] b), take 1g lactoferrin, 0.1g immunoglobulin and 10g bovine colostrum extract respectively, dissolve in 100g water for injection to prepare a solution;

[0037] c), take by weighing 1g lysozyme, 0.1g lactoperoxidase respectively, be dissolved in 100g water for injection preparation solution;

[0038] d), the solution prepared by step a), step b), 10g xylitol, 1g ethylparaben and 8g mint essence were mixed in the remaining 562.8g water for injection, and slowly stirred;

[0039] e) Add the solution prepared in step c) to the solution prepared in step d), stir until uniform, subpackage it into an oral sprayer with a suction nozzle, and sterilize it at 85°C for 15 minutes to obtain a finished product. ...

Embodiment 2

[0051] Two. preparation gross weight is the oral cavity spray of the oral cavity inflammatory disease of 1000g:

[0052]a), take by weighing 10g hydroxyethyl chitosan, 50g propolis extract respectively, be dissolved in the preparation solution in 200g water for injection;

[0053] b), take 3g lactoferrin, 0.5g immunoglobulin and 20g bovine colostrum extract respectively, dissolve in 100g water for injection to prepare a solution;

[0054] c), take by weighing 5g lysozyme, 1g lactoperoxidase respectively, be dissolved in the preparation solution in 100g water for injection;

[0055] d), the solution prepared in step a), step b), 20g of maltitol, 5g of methylparaben and 10g of peppermint essence were mixed into the remaining 475.5g of water for injection, and slowly stirred;

[0056] e) Add the solution prepared in step c) to the solution prepared in step d), stir until uniform, subpackage it into an oral sprayer with a suction nozzle, and sterilize it at 85°C for 15 minutes to...

Embodiment 3

[0068] 3. prepare the oral cavity spray that gross weight is the oral cavity inflammatory disease of 1000g:

[0069] a), take by weighing 50g hydroxypropyl chitosan, 20g propolis extract respectively, be dissolved in the preparation solution in 200g water for injection;

[0070] b), take by weighing 10g lactoferrin, 5g immunoglobulin and 100g bovine colostrum extract respectively, dissolve in 200g water for injection to prepare a solution;

[0071] c), take by weighing 2g lysozyme, 5g lactoperoxidase respectively, be dissolved in the preparation solution in 100g water for injection;

[0072] d), the solution prepared by step a), step b), 50g stevioside, 10g propylparaben and 12g peppermint essence were mixed in the remaining 236g water for injection, and stirred slowly;

[0073] e) Add the solution prepared in step c) to the solution prepared in step d), stir until uniform, subpackage it into an oral sprayer with a suction nozzle, and sterilize it at 85°C for 15 minutes to ob...

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Abstract

The invention relates to an oral spray for inflammatory diseases of the oral cavity and a preparation method thereof. The oral spray comprises the following components: 0.1-5% of water-soluble chitosan, 0.5-5% of propolis extract, 0.1-1% of lactoferrin, 0.01-0.5% of lactoperoxidase, 0.1-0.5% of lysozyme, 0.01-0.1% of immunoglobulin, 1-10% of bovine colostrum extract, 1-10% of anti-caries sweetener, 0.8-1.2% of cold aromatic, 0.1-1% of preservative and the balance of water for injections. The preparation method is characterized by mixing the components, stirring uniformly, filling into an oral sprayer, and sterilizing at 85 DEG C for 15 minutes to obtain the finished product. The oral spray has the effect of immediately and rapidly treating inflammatory diseases of the oral cavity and the functions of resisting bacteria and viruses, relieving pains, reducing gum inflammation and blooding, promoting the healing of oral ulcer wounds, treating acute and chronic pharyngitis, moistening and freshening the oral cavity and removing halitosis. The oral spray has the advantages of simple and convenient large-scale production process and no environmental pollution in the production process.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an oral spray for oral inflammatory diseases and a preparation method thereof. Background technique [0002] Oral inflammatory disease is a common and frequently-occurring disease, and almost everyone has suffered from oral inflammatory disease. It is generally divided into three categories according to the etiology: 1. Infectious stomatitis, which refers to inflammation of the oral mucosa caused by infection of pathogenic microorganisms such as bacteria, viruses or molds; 2. Dystrophic stomatitis, which is oral inflammation caused by lack of vitamins 3. Immune stomatitis refers to an oral inflammatory disease caused by autoimmune factors. Pain, hyperemia and edema of oral mucosa, and herpes and ulcers of different sizes are the main symptoms of oral inflammatory diseases. [0003] Oral inflammatory diseases, such as oral ulcers, pharyngitis, laryngitis, tonsilliti...

Claims

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Application Information

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IPC IPC(8): A61K39/395A61K9/12A61P1/02A61P31/02A61P31/12A61P29/00A61P7/04A61P11/04A61K31/722A61K38/40A61K38/44A61K38/47A61K35/20A61K35/64A61K35/644
Inventor 官培龙黄利苹谭伟
Owner 武汉耦合医学科技有限责任公司
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