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Self-assembly nano-medicament bi-stable quantum wire array and preparation method thereof

A nano-drug and self-assembly technology, applied in nanotechnology, nanotechnology, nanotechnology for information processing, etc., to achieve the effect of regular geometric configuration and controllable scale

Active Publication Date: 2011-09-07
ZHONGSHAN HOSPITAL FUDAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Previous studies have shown that iapamidine, isoproterenol, superoxide dismutase, and adenosine triphosphate are a group of drug molecular networks with nanoscale size, charge transport and target recognition capabilities, but so far have not been seen at the single-molecule level, nanomedicine Report on Bistable Quantum Wire Array and Its Preparation Method

Method used

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  • Self-assembly nano-medicament bi-stable quantum wire array and preparation method thereof
  • Self-assembly nano-medicament bi-stable quantum wire array and preparation method thereof
  • Self-assembly nano-medicament bi-stable quantum wire array and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Prepare the following medicinal solution according to the Pharmacopoeia specification issued by the Ministry of Health of the People's Republic of China:

[0051] 1. Preparation of Ibopridine Hydrochloride Solution 2.5 mg / 5 mL

[0052] 2. Prepare a solution containing 2 mg / 100 ml of isoproterenol hydrochloride

[0053] 3. Preparation of Physiological Salt Buffer Containing 1 mg / 2 mL Superoxide Dismutase

[0054] 4. Preparation of Physiological Salt Buffer Containing 20 mg / 3.3 mL ATP

[0055] 5. Take the optimal solute number of each component within the ratio range of 1:1:1:1, mix evenly at room temperature, add physiological saline buffer solution to 1 ml, store at -4°C for later use.

[0056] 6. Use 8-12 ohm.cm P-type silicon wafers as the substrate for self-assembled quantum wires, and self-assemble the above-mentioned pharmaceutical-grade nanomedicines on the silicon wafer substrate according to the L9(3)4 scheme, -4 ℃ for 96 hours.

[0057] The results show tha...

Embodiment 2

[0059] Prepare the following medicinal solution according to the Pharmacopoeia specification issued by the Ministry of Health of the People's Republic of China:

[0060] 1. Preparation of Ibopridine Hydrochloride Solution 2.5 mg / 5 mL

[0061] 2. Prepare a solution containing 2 mg / 100 ml of isoproterenol hydrochloride

[0062] 3. Preparation of Physiological Salt Buffer Containing 1 mg / 2 mL Superoxide Dismutase

[0063] 4. Preparation of Physiological Salt Buffer Containing 20 mg / 3.3 mL ATP

[0064] 5. Take the optimal solute number of each component within the ratio range of 1:2:2:2, mix evenly at room temperature, add physiological saline buffer solution to 1 ml, and store at -4°C for later use.

[0065] 6. Use 8-12 ohm.cm P-type silicon wafers as the substrate for self-assembled quantum wires, and self-assemble the above-mentioned pharmaceutical-grade nanomedicines on the silicon wafer substrate according to the L9(3)4 scheme, -4 ℃ for 96 hours.

[0066] As a result, a q...

Embodiment 3

[0068] Prepare the following medicinal solution according to the Pharmacopoeia specification issued by the Ministry of Health of the People's Republic of China:

[0069] 1. Preparation of Ibopridine Hydrochloride Solution 2.5 mg / 5 mL

[0070] 2. Prepare a solution containing 2 mg / 100 ml of isoproterenol hydrochloride

[0071] 3. Preparation of Physiological Salt Buffer Containing 1 mg / 2 mL Superoxide Dismutase

[0072] 4. Preparation of Physiological Salt Buffer Containing 20 mg / 3.3 mL ATP

[0073] 5. Take the optimal solute number of each component within the ratio range of 1:3:3:3, mix evenly at room temperature, add physiological saline buffer solution to 1 ml, and store at -4°C for later use.

[0074] 6. Use 8-12 ohm.cm P-type silicon wafers as the substrate for self-assembled quantum wires, and self-assemble the above-mentioned pharmaceutical-grade nanomedicines on the silicon wafer substrate according to the L9(3)4 scheme, -4 ℃ for 96 hours.

[0075] The results show...

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Abstract

The invention relates to the field of advanced quantum information materials, in particular relating to a self-assembly nano-medicament bi-stable quantum wire array and a preparation method thereof. The self-assembly nano-medicament bi-stable quantum wire array is prepared by self-assembling an antioxidase oxygen radical antagonist, a beta-receptor agonist, a P2 receptor agonist, a benzene alkyl amine calcium antagonist and / or a purine nucleic acid monomer as well as binary, ternary, quaternary and quinary complexes of the components under interaction of inelastic electron tunneling. The quantum wire array has the advantages of regular geometric structure, controllable and adjustable dimension, inelastic electron tunneling and quantum bit electrical properties and kondo effect. The self-assembly nano-medicament bi-stable quantum wire array and the preparation method thereof are beneficial to research of innovative medicaments with a targeted disease mechanism and research of a new quantum biological information sensing material and a nano-structured magnetic random access memory (MRAM).

Description

[0001] This application is a divisional application of the Chinese invention patent application submitted on July 15, 2005 with the application number 200510027795.6 and the title of the invention is "Nanomedicine Self-Assembled Bistable Quantum Wire Array and Preparation Method". technical field [0002] The invention relates to the field of artificial polymer molecular quantum information materials, in particular to a nano drug self-assembled bistable quantum wire array and a preparation method thereof. Background technique [0003] Quantum wire is the core of the development of quantum computing and ultrafast or ultrasensitive diagnostic technology and nanobiological sensing, and qubit is the current research hotspot of information materials. The development of biomolecules as information material construction components is a hot spot of modern and long-term research at home and abroad. Previous studies have shown that iapamidine, isoproterenol, superoxide dismutase, and ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00B82Y10/00G01N27/00
Inventor 方琰吴荣
Owner ZHONGSHAN HOSPITAL FUDAN UNIV
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