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Method for preparing novel medical lubricating antibacterial catheter

A technology for medical catheters and catheters, applied in catheters and other directions, can solve problems such as reduced effect, and achieve the effects of environmental protection, uniform dispersion and good lubricity of materials.

Active Publication Date: 2011-09-28
SHANGHAI LANGYI FUNCTIONAL MATERIALS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, more surface coatings are still used. Similar to the realization of lubricating coatings, although surface coatings can achieve antibacterial properties within a certain period of time, their effects will rapidly decrease with the rupture of the surface film, such as CN101428157A

Method used

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  • Method for preparing novel medical lubricating antibacterial catheter
  • Method for preparing novel medical lubricating antibacterial catheter

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Example 1 1000 g of polypropylene-based nano-silver antibacterial powder with a silver concentration of 2000 ppm and 3000 g of polylactic acid slices were passed through a screw extruder. Blending and extruding at 175-220°C to prepare polylactic acid antibacterial mother slices; then through a precision melting extruder to prepare lubricated antibacterial medical catheters containing 500ppm silver.

Embodiment 2

[0022] Example 2: 1000g of polypropylene-based nano-silver antibacterial powder with a silver concentration of 10000ppm and 4000g of polylactic acid slices are passed through a screw extruder, and blended and extruded at 175-220°C to prepare polylactic acid antibacterial mother slices; A melt extruder prepares a lubricated antibacterial medical catheter containing silver 200ppm.

Embodiment 3

[0023] Example 3: 1000g of polypropylene-based nano-silver antibacterial powder with a silver concentration of 10000ppm and 7000g of polylactic acid slices are passed through a screw extruder, and blended and extruded at 175-220°C to prepare polylactic acid antibacterial mother slices; A melt extruder prepares a lubricated antibacterial medical catheter containing silver 125ppm.

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Abstract

The invention discloses a method for preparing a novel medical lubricating antibacterial catheter, which comprises the following steps of: blending and extruding high-concentration polypropylene-based nanometer silver antibacterial powder or antibacterial master batches and polylactic acid slices by using a screw extruder to prepare polylactic acid antibacterial master slices; and preparing the medical lubricating antibacterial catheter by using a precision melting extruder. The method is obvious in bacteriostatic effect, bacteria on the surface of the catheter can be inhibited from being propagated effectively, and the efficiency is more than 98 percent; and the catheter prepared by the method is high in biocompatibility, has surface self-lubricating property, and can be widely used for the water delivery and transfusion of patients and relevant instruments.

Description

Technical field [0001] The invention relates to a preparation method of a medical catheter, in particular to a preparation method of a novel medical lubricating and antibacterial catheter with self-lubricating properties, good antibacterial properties and long-lasting antibacterial effect. Background technique [0002] With the development of interventional medicine, people gradually realize the important role of medical catheters. With the help of medical catheters, people have realized many therapeutic functions such as disease diagnosis, treatment, sewage discharge, and laboratory tests. In order to further alleviate the suffering of patients and reduce wound infection, people continue to improve catheters. [0003] Lubricity is an important indicator of medical catheter materials. At present, in order to achieve the lubricity of the catheter, the surface of the catheter is usually modified by coating the surface of the catheter with a highly hydrophilic polymer. For exa...

Claims

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Application Information

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IPC IPC(8): A61L29/06A61L29/02A61L29/14
Inventor 唐晓峰赵宏鑫
Owner SHANGHAI LANGYI FUNCTIONAL MATERIALS
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