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Preparation of Magnolia flower volatile oil soft capsule for treating allergic rhinitis and associated diseases

A technology for allergic rhinitis and volatile oil, which can be used in allergic diseases, capsule delivery, respiratory diseases, etc., and can solve problems such as hyposmia and disappearance

Inactive Publication Date: 2011-10-26
陈世忠 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Clinically, the main symptoms are sudden nasal itching, sneezing, and runny nose. In severe cases, the sense of smell decreases or disappears, which brings great pain to the patient.

Method used

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  • Preparation of Magnolia flower volatile oil soft capsule for treating allergic rhinitis and associated diseases
  • Preparation of Magnolia flower volatile oil soft capsule for treating allergic rhinitis and associated diseases
  • Preparation of Magnolia flower volatile oil soft capsule for treating allergic rhinitis and associated diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0064] Example 1 Preparation of Xinyi Soft Capsules

[0065] 1. Preparation of magnolia volatile oil

[0066] Take magnolia magnolia medicinal material 10kg, crush it into coarse powder, put it in a volatile oil extractor, add 120kg of demineralized water, soak for 8 hours, heat and distill for 9 hours, and collect the volatile oil; dehydrate the collected volatile oil with a small amount of anhydrous sodium sulfate to obtain a transparent light yellow volatile oil.

[0067] 2. Preparation of the contents of magnolia volatile oil soft capsules

[0068] Get above-mentioned magnolia volatile oil 300ml, add soybean oil 340ml, propylene glycol 30ml, mix well, obtain the magnolia volatile oil soft capsule content.

[0069] 3. Molding of magnolia volatile oil soft capsules

[0070] Take the content of the above-mentioned magnolia volatile oil soft capsules, put them in a soft capsule machine, adjust the rotating speed of the soft capsule machine, control the filling volume, and ...

Embodiment 2

[0073] Example 2 Preparation of Xinyi Soft Capsules

[0074] 1. Preparation of Magnolia Magnolia Volatile Oil

[0075] Take magnolia magnolia medicinal material 10kg, crush it into coarse powder, put it in a volatile oil extractor, add 120kg of demineralized water, soak for 8 hours, heat and distill for 9 hours, and collect the volatile oil; dehydrate the collected volatile oil with a small amount of anhydrous sodium sulfate to obtain a transparent light yellow volatile oil.

[0076] 2. Preparation of the contents of magnolia volatile oil soft capsules

[0077] Get above-mentioned magnolia volatile oil 300ml, add soybean oil 250ml, propylene glycol 30ml, lecithin 90ml, mix evenly, obtain the magnolia volatile oil soft capsule content.

[0078] 3. Molding of magnolia volatile oil soft capsules

[0079] Take the content of the above-mentioned magnolia volatile oil soft capsules, put them in a soft capsule machine, adjust the rotating speed of the soft capsule machine, contr...

Embodiment 3-5

[0082] Example 3-5 Preparation of Magnolia Volatile Oil Soft Capsules

[0083] In Example 2-4, 300ml of magnolia volatile oil, 250ml of soybean oil, 30ml of propylene glycol, and 90ml of lecithin were added, and its extract and soft capsule were prepared according to the preparation method of Example 1, and its yield was investigated. The results are shown in Table 1.

[0084] The composition of table 1 embodiment 2-4 drop pill and investigation into yield

[0085]

[0086] The results show that the soft capsule of the present invention has the advantages of stable production process, high product pass rate, and stable quality.

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Abstract

The invention relates to a preparation method and an application of a Magnolia flower volatile oil soft capsule for treating allergic rhinitis and associated diseases. The Magnolia flower volatile oil soft capsule contains the following ingredients in parts by volume: 1 to 90 parts of Magnolia flower volatile oil, 10 to 90 parts of oil phase, 0 to 50 parts of emulsifier and 0 to 30 of co-solvent. The Magnolia flower volatile oil soft capsule, provided by the invention, is also available in the form of an enteric-coated soft capsule, so as to reduce irritation to the stomach and enhance the patient compliance. The soft capsule provided by the invention is used for treating allergic rhinitis, acute rhinitis, simple rhinitis, hypertrophic rhinitis, atrophic rhinitis, acute nasosinusitis, chronic nasosinusitis or complications thereof, as well as respiratory diseases such as acute upper respiratory infection, acute / chronic obstructive lung disease and asthma, with remarkable curative effects.

Description

technical field [0001] The invention relates to a preparation method of magnolia volatile oil soft capsules for treating allergic rhinitis and related diseases. Background technique [0002] Allergic rhinitis (Allergicrhinetis, AR) is a kind of non-infectious inflammation mainly caused by type I hypersensitivity caused by inhalation of external allergens by susceptible individuals. Lord's disease. Clinically, it is characterized by nasal congestion, nasal itching, runny nose, and sneezing. It is clinically defined as a series of nasal symptoms caused by IgE-mediated inflammatory reactions after the nasal mucosa contacts allergens. One of the most common diseases. The 31 member countries of the International Federation of Otorhinolaryngology Societies (IFOR) comprehensively reported that the prevalence of AR population is about 20%. As of 2009, according to the self-reported prevalence rate in central cities, it is conservatively estimated that the actual number of AR pati...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/575A61K9/48A61K47/34A61K47/38A61K47/42A61K47/44A61P11/00A61P11/02A61P11/06A61P37/08
Inventor 陈世忠侯建平王弘
Owner 陈世忠
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