Application of medicinal composition in preparing medicaments for treating diabetes mellitus and impaired glucose tolerance

A technology for impaired glucose tolerance and a composition is applied in the application field of pharmaceutical compositions in the preparation of medicines for the treatment of diabetes and impaired glucose tolerance, and can solve the problems of neglecting the regulation of glucose metabolism disorders and the like

Active Publication Date: 2012-05-09
SHAANXI BUCHANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are the following problems in the treatment of glucose and lipid metabolism disorders: (1) Most of the hypoglycemic and lipid-lowering western medicines have side effects such as drug withdrawal rebound, liver and kidney damage, gastrointestinal reactions, and allergic reactions to varying degrees; Sugar Chinese patent medicines take the normalization of blood sugar as the basic goal of treatment and the key to solving problems,

Method used

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  • Application of medicinal composition in preparing medicaments for treating diabetes mellitus and impaired glucose tolerance
  • Application of medicinal composition in preparing medicaments for treating diabetes mellitus and impaired glucose tolerance
  • Application of medicinal composition in preparing medicaments for treating diabetes mellitus and impaired glucose tolerance

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Embodiment Construction

[0024]1. Preparation method of granules: take 120g of Jujube, pulverize into fine powder, divide into two parts, and set aside; take 360g of Jujube and pulverize into the coarsest powder, percolate with 70% ethanol, collect percolation, reclaim ethanol, Concentrate to a relative density of 1.30-1.35 (60°C), add a portion of jujube fine powder, mix well, dry under vacuum at 60°C, and crush into fine powder. Extract 240g of Salvia miltiorrhiza for 3 times, add ethanol to reflux for 1.5 hours for the first time, filter, recover ethanol from the filtrate, concentrate to a relative density of 1.30 (55-60°C); add 50% ethanol for the second time, reflux for 1.5 hours, filter; Add water three times and decoct for 2 hours, filter, combine the second and third filtrates, recover ethanol, concentrate to a relative density of 1.40 (55-60°C), combine with the first concentrate, mix well, and concentrate to a relative density 1.20~1.30 (55~60°C), add another portion of jujube fine powder, m...

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Abstract

The invention relates to novel application of a medicinal composition in preparing medicaments for treating diabetes mellitus and impaired clucose tolerance. The medicinal composition comprises 480 parts of axillary choerospondias fruit, 240 parts of red-rooted salvia root, 60 parts of clove, 30 parts of borneol, and 30 parts of tabasheer. The medicinal composition can be pills, granules, hard capsules, soft capsules, tablets, dripping pills or oral liquid. The invention aims at providing novel treatment application of the medicinal composition, so that the clinical application range of the medicinal composition provided by the invention is enlarged, and waste of excellent medicinal resources is avoided.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of a pharmaceutical composition in the preparation of medicines for treating diabetes and impaired glucose tolerance. Background technique [0002] Pre-diabetes, including Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT), refers to an intermediate state in which the patient's blood sugar is between the normal blood sugar level and the blood sugar level of diabetic patients. The 2008 guidelines for the clinical diagnosis and treatment of diabetes formulated by the American Diabetes Association (ADA) pointed out that the diagnostic criteria for prediabetes are: impaired fasting blood glucose (fasting blood glucose value FPG is 5.6-6.9mmol / L) & / or impaired glucose tolerance (fasting blood glucose value FPG< 7mmol / L & 2h postprandial blood glucose value in glucose tolerance test (OGTT 2hPG 7.8~11.0mmol / L). [0003] Prediabetes is an intermedi...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P3/10A61K31/045
Inventor 赵涛
Owner SHAANXI BUCHANG PHARMA
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