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Compound propolis composition for treating swine infectious atrophic rhinitis and preparation method thereof

A technology of atrophic rhinitis and compound propolis, which is applied in the direction of drug combination, effective ingredients of hydroxyl compounds, medical preparations containing active ingredients, etc., can solve problems such as restrictions on the use of antibacterial drugs, unreasonable prescriptions, and low bioavailability. Achieve step-by-step mixing evenly, ensure good health and high bioavailability

Inactive Publication Date: 2012-06-13
QINGDAO LVMAN BIOLOGICAL ENG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, traditional Chinese medicine and antibacterial drugs are the most commonly used to treat this disease. Traditional Chinese medicine is not very effective because of its unreasonable formula or simply crushed, too large particle size and slow drug release, resulting in low bioavailability. ; Due to long-term use of antibacterial drugs, there are drug residues and drug resistance, their clinical effect is getting worse, and drug residues lead to export restrictions and endanger people's health, so that the use of antibacterial drugs is greatly restricted

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] A compound propolis composition for treating porcine infectious atrophic rhinitis and a preparation method thereof: the steps are as follows: (each part is calculated as 10g)

[0027] (1) passing through a 700-mesh sieve after ultrafine pulverization of various components in the prescription;

[0028] (2) Take by weight 150 parts of propolis, 150 parts of tooth soap, 150 parts of Angelica dahurica, 150 parts of Asarum, and mix for 5-10 minutes until uniform;

[0029] (3) Weigh 150 parts of borneol, 100 parts of realgar, 150 parts of mint, and 100 parts of mugwort leaves by weight, and mix for 5-10 minutes until uniform;

[0030] (4) Combine the compositions prepared in the steps (2) and (3) above, and continue mixing for 10-15 minutes until uniform.

Embodiment 2

[0032] A compound propolis composition for treating porcine infectious atrophic rhinitis and a preparation method thereof: the steps are as follows: (each part is calculated as 10g)

[0033] (1) passing through a 700-mesh sieve after ultrafine pulverization of various components in the prescription;

[0034] (2) Take by weight 250 parts of propolis, 250 parts of tooth soap, 250 parts of Angelica dahurica, and 250 parts of Asarum, and mix for 5-10 minutes until uniform;

[0035] (3) Weigh 300 parts of borneol, 150 parts of realgar, 300 parts of peppermint, and 150 parts of mugwort leaves by weight, and mix for 5-10 minutes until uniform;

[0036] (4) Combine the compositions prepared in the steps (2) and (3) above, and continue mixing for 10-15 minutes until uniform.

Embodiment 3

[0038] A compound propolis composition for treating porcine infectious atrophic rhinitis and a preparation method thereof: the steps are as follows: (each part is calculated as 10g)

[0039] (1) passing through a 700-mesh sieve after ultrafine pulverization of various components in the prescription;

[0040] (2) Take by weight 350 parts of propolis, 350 parts of tooth soap, 350 parts of Angelica dahurica, 350 parts of Asarum, and mix for 5-10 minutes until uniform;

[0041] (3) Take 450 parts of borneol, 200 parts of realgar, 450 parts of mint, and 300 parts of Artemisia argyi by weight, and mix for 5-10 minutes until uniform;

[0042] (4) Combine the compositions prepared in the steps (2) and (3) above, and continue mixing for 10-15 minutes until uniform.

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PUM

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Abstract

The invention relates to a compound propolis composition for treating swine infectious atrophic rhinitis and a preparation method thereof, which relates to the field of animal medicines. The preparation method for the composition comprises the following steps: (1) respectively carrying out ultrafine crushing on all the components in a prescription and screening all the crushed components with a 700-mesh sieve; (2) weighing 15 to 35 parts by weight of propolis, 15 to 35 parts by weight of fructus gleditsiae abnormalis, 15 to 35 parts by weight of dahurian angelica root and 15 to 35 parts by weight of Asarum herb and uniformly mixing the components for 5 to 10 min; (3) weighing 15 to 45 parts by weight of borneol, 10 to 20 parts by weight of realgar, 15 to 45 parts by weight of mint and 10 to 30 parts by weight of tarragon and uniformly mixing the components for 5 to 10 min; and (4) combining compositions prepared in step (2) and (3) and continuing to uniformly mix the compositions for 10 to 15 min so as to obtain the compound propolis composition. The beneficial effects of the invention are as follows: composition is reasonable; preparation is simple; the compound propolis composition has the advantages of no toxic and side effects, no pollution, no drug residue, no drug resistance, a unique application method of direct blowing of the compound propolis composition into noses of infected animals, ultrafine crushing, high bioavailability and a very remarkable curative effect, and according to results of clinical practice, the compound propolis composition has special efficacy in treating swine infectious atrophic rhinitis.

Description

technical field [0001] The invention relates to the field of animal medicine, in particular to a compound propolis composition specially used for treating porcine infectious atrophic rhinitis and a preparation method thereof. Background technique [0002] Porcine infectious atrophic rhinitis is a worldwide widespread and widespread severe contact upper respiratory infectious disease caused by porcine toxin-producing Pasteurella multocida and Bordetella bronchiseptica. Clinically, sneezing, It is characterized by deformation of the nasal bones, atrophy or disappearance of the turbinates, and curvature of the nasal septum. Pigs of various ages and breeds can occur, and the case fatality rate is between 2% and 10%. Infected pigs can cause serious increase in feed consumption and delay in slaughtering. The disease can occur throughout the year and is one of the major diseases that seriously endanger the pig industry. [0003] The disease is spread widely in almost all pig-rais...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/534A61P11/02A61P31/04A61K31/045A61K33/36A61K35/64A61K35/644
Inventor 周庆福刘文利
Owner QINGDAO LVMAN BIOLOGICAL ENG
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